Detailed information NTG0561955

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV31_RS04980
• Genome accession: NZ_CP073890
• Coordinates: 946535..947581 (+)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain V1933793
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 941535..952581

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV31_RS04955 (KFV31_04955)	-	942676..943212 (+)	537	WP_002470337.1	hypothetical protein	-
KFV31_RS04960 (KFV31_04960)	-	943363..944349 (-)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV31_RS04965 (KFV31_04965)	map	944523..945278 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV31_RS04970 (KFV31_04970)	-	945436..945822 (+)	387	WP_001830382.1	hypothetical protein	-
KFV31_RS04975 (KFV31_04975)	liaF	945837..946538 (+)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV31_RS04980 (KFV31_04980)	vraS	946535..947581 (+)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV31_RS04985 (KFV31_04985)	vraR	947571..948200 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV31_RS04990 (KFV31_04990)	-	948257..949435 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV31_RS04995 (KFV31_04995)	-	949842..950126 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV31_RS05000 (KFV31_05000)	-	950134..950598 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV31_RS05005 (KFV31_05005)	-	950739..950954 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV31_RS05010 (KFV31_05010)	-	950956..952197 (+)	1242	WP_001832467.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561955 KFV31_RS04980 WP_001830374.1 946535..947581(+) (vraS) [Staphylococcus epidermidis strain V1933793]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561955 KFV31_RS04980 WP_001830374.1 946535..947581(+) (vraS) [Staphylococcus epidermidis strain V1933793]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92