Detailed information NTG0561875

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV54_RS03485
• Genome accession: NZ_CP073883
• Coordinates: 659630..660676 (+)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain B1287175
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 654630..665676

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV54_RS03460 (KFV54_03460)	-	655771..656307 (+)	537	WP_002470337.1	hypothetical protein	-
KFV54_RS03465 (KFV54_03465)	-	656458..657444 (-)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV54_RS03470 (KFV54_03470)	map	657618..658373 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV54_RS03475 (KFV54_03475)	-	658531..658917 (+)	387	WP_001830382.1	hypothetical protein	-
KFV54_RS03480 (KFV54_03480)	liaF	658932..659633 (+)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV54_RS03485 (KFV54_03485)	vraS	659630..660676 (+)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV54_RS03490 (KFV54_03490)	vraR	660666..661295 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV54_RS03495 (KFV54_03495)	-	661352..662530 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV54_RS03500 (KFV54_03500)	-	662937..663221 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV54_RS03505 (KFV54_03505)	-	663229..663693 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV54_RS03510 (KFV54_03510)	-	663834..664049 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV54_RS03515 (KFV54_03515)	-	664051..665292 (+)	1242	WP_001832467.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561875 KFV54_RS03485 WP_001830374.1 659630..660676(+) (vraS) [Staphylococcus epidermidis strain B1287175]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561875 KFV54_RS03485 WP_001830374.1 659630..660676(+) (vraS) [Staphylococcus epidermidis strain B1287175]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92