Detailed information NTG0561784

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV37_RS08375
• Genome accession: NZ_CP073876
• Coordinates: 1765749..1766795 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain B1285135
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1760749..1771795

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV37_RS08345 (KFV37_08385)	-	1761133..1762374 (-)	1242	WP_001832467.1	aminopeptidase	-
KFV37_RS08350 (KFV37_08390)	-	1762376..1762591 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV37_RS08355 (KFV37_08395)	-	1762732..1763196 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV37_RS08360 (KFV37_08400)	-	1763204..1763488 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV37_RS08365 (KFV37_08405)	-	1763895..1765073 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV37_RS08370 (KFV37_08410)	vraR	1765130..1765759 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV37_RS08375 (KFV37_08415)	vraS	1765749..1766795 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV37_RS08380 (KFV37_08420)	liaF	1766792..1767493 (-)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV37_RS08385 (KFV37_08425)	-	1767508..1767894 (-)	387	WP_001830382.1	hypothetical protein	-
KFV37_RS08390 (KFV37_08430)	map	1768052..1768807 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV37_RS08395 (KFV37_08435)	-	1768981..1769967 (+)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV37_RS08400 (KFV37_08440)	-	1770118..1770654 (-)	537	WP_002470337.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561784 KFV37_RS08375 WP_001830374.1 1765749..1766795(-) (vraS) [Staphylococcus epidermidis strain B1285135]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561784 KFV37_RS08375 WP_001830374.1 1765749..1766795(-) (vraS) [Staphylococcus epidermidis strain B1285135]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92