Detailed information NTG0561746

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV34_RS08380
• Genome accession: NZ_CP073872
• Coordinates: 1768376..1769422 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain B1282731
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1763376..1774422

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV34_RS08350 (KFV34_08360)	-	1763760..1765001 (-)	1242	WP_001832467.1	aminopeptidase	-
KFV34_RS08355 (KFV34_08365)	-	1765003..1765218 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV34_RS08360 (KFV34_08370)	-	1765359..1765823 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV34_RS08365 (KFV34_08375)	-	1765831..1766115 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV34_RS08370 (KFV34_08380)	-	1766522..1767700 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV34_RS08375 (KFV34_08385)	vraR	1767757..1768386 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV34_RS08380 (KFV34_08390)	vraS	1768376..1769422 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV34_RS08385 (KFV34_08395)	liaF	1769419..1770120 (-)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV34_RS08390 (KFV34_08400)	-	1770135..1770521 (-)	387	WP_001830382.1	hypothetical protein	-
KFV34_RS08395 (KFV34_08405)	map	1770679..1771434 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV34_RS08400 (KFV34_08410)	-	1771608..1772594 (+)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV34_RS08405 (KFV34_08415)	-	1772745..1773281 (-)	537	WP_002470337.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561746 KFV34_RS08380 WP_001830374.1 1768376..1769422(-) (vraS) [Staphylococcus epidermidis strain B1282731]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561746 KFV34_RS08380 WP_001830374.1 1768376..1769422(-) (vraS) [Staphylococcus epidermidis strain B1282731]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92