Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | KFV34_RS00615 | Genome accession | NZ_CP073872 |
| Coordinates | 112131..113477 (-) | Length | 448 a.a. |
| NCBI ID | WP_000816499.1 | Uniprot ID | Q9R3W9 |
| Organism | Staphylococcus epidermidis strain B1282731 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 64816..113477 | 112131..113477 | within | 0 |
Gene organization within MGE regions
Location: 64816..113477
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFV34_RS00360 (KFV34_00360) | ccrB | 64816..66444 (-) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| KFV34_RS00365 (KFV34_00365) | ccrA | 66441..67802 (-) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| KFV34_RS00370 (KFV34_00370) | - | 67989..68618 (-) | 630 | Protein_55 | hypothetical protein | - |
| KFV34_RS00375 (KFV34_00375) | - | 68627..68965 (+) | 339 | Protein_56 | recombinase family protein | - |
| KFV34_RS00380 (KFV34_00380) | - | 69077..69436 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| KFV34_RS00385 (KFV34_00385) | - | 69643..69969 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV34_RS00390 (KFV34_00390) | - | 70299..72224 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| KFV34_RS00395 (KFV34_00395) | - | 73476..73781 (+) | 306 | WP_000677987.1 | hypothetical protein | - |
| KFV34_RS00400 (KFV34_00400) | - | 73979..74842 (+) | 864 | WP_000680579.1 | hypothetical protein | - |
| KFV34_RS00405 (KFV34_00405) | - | 74950..76425 (+) | 1476 | WP_001138664.1 | DUF6038 family protein | - |
| KFV34_RS00410 (KFV34_00410) | - | 76652..77752 (+) | 1101 | WP_000449985.1 | DNA polymerase | - |
| KFV34_RS00415 (KFV34_00415) | - | 77745..78116 (+) | 372 | WP_001058157.1 | hypothetical protein | - |
| KFV34_RS00420 (KFV34_00420) | - | 78113..79756 (+) | 1644 | WP_012086574.1 | DUF5906 domain-containing protein | - |
| KFV34_RS00425 (KFV34_00425) | - | 79983..81659 (+) | 1677 | WP_012086571.1 | recombinase family protein | - |
| KFV34_RS00430 (KFV34_00430) | - | 81765..82103 (+) | 339 | WP_012086569.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV34_RS00435 (KFV34_00435) | - | 82199..82510 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| KFV34_RS00440 (KFV34_00440) | - | 82526..83032 (+) | 507 | WP_012086564.1 | DUF1643 domain-containing protein | - |
| KFV34_RS00445 (KFV34_00445) | - | 83060..83506 (+) | 447 | WP_012086562.1 | JAB domain-containing protein | - |
| KFV34_RS00450 (KFV34_00450) | - | 83676..84548 (+) | 873 | WP_012086560.1 | HTH domain-containing protein | - |
| KFV34_RS00455 (KFV34_00455) | - | 84600..84890 (+) | 291 | WP_012086558.1 | hypothetical protein | - |
| KFV34_RS00465 (KFV34_00465) | - | 85113..85268 (+) | 156 | Protein_73 | metal-sensing transcriptional repressor | - |
| KFV34_RS00470 (KFV34_00470) | - | 85265..86023 (+) | 759 | WP_000623679.1 | sulfite exporter TauE/SafE family protein | - |
| KFV34_RS00475 (KFV34_00475) | - | 86193..86402 (+) | 210 | Protein_75 | heavy metal translocating P-type ATPase | - |
| KFV34_RS00480 (KFV34_00480) | - | 86420..86965 (+) | 546 | WP_031869236.1 | YdhK family protein | - |
| KFV34_RS00485 (KFV34_00485) | - | 87408..88664 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| KFV34_RS00490 (KFV34_00490) | - | 89109..89783 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KFV34_RS00495 (KFV34_00495) | - | 89867..90208 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| KFV34_RS00500 (KFV34_00500) | - | 91005..91748 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KFV34_RS00505 (KFV34_00505) | - | 91845..92273 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KFV34_RS00510 (KFV34_00510) | mecA | 92319..94328 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KFV34_RS00515 (KFV34_00515) | mecR1 | 94425..96182 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KFV34_RS00520 (KFV34_00520) | mecI | 96182..96553 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KFV34_RS00525 (KFV34_00525) | psm-mec | 96638..96706 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KFV34_RS00530 (KFV34_00530) | - | 97040..98170 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| KFV34_RS00535 (KFV34_00535) | cstB | 98284..99618 (-) | 1335 | Protein_87 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KFV34_RS00540 (KFV34_00540) | - | 99651..100715 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KFV34_RS00545 (KFV34_00545) | cstR | 100851..101111 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KFV34_RS00550 (KFV34_00550) | - | 101111..101749 (+) | 639 | Protein_90 | sulfite exporter TauE/SafE family protein | - |
| KFV34_RS00560 (KFV34_00560) | - | 102023..102639 (-) | 617 | Protein_91 | CadD family cadmium resistance transporter | - |
| KFV34_RS00565 (KFV34_00565) | - | 102720..105134 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| KFV34_RS00570 (KFV34_00570) | - | 105127..105492 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV34_RS00575 (KFV34_00575) | - | 105730..106107 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| KFV34_RS00580 (KFV34_00580) | - | 106114..108006 (-) | 1893 | WP_002485298.1 | site-specific integrase | - |
| KFV34_RS00585 (KFV34_00585) | - | 108201..108524 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| KFV34_RS00590 (KFV34_00590) | - | 108517..108723 (-) | 207 | WP_001077283.1 | hypothetical protein | - |
| KFV34_RS00595 (KFV34_00595) | - | 108725..109246 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| KFV34_RS00600 (KFV34_00600) | - | 109265..109576 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| KFV34_RS00605 (KFV34_00605) | - | 109661..110011 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV34_RS00610 (KFV34_00610) | ccrB | 110482..112110 (-) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| KFV34_RS00615 (KFV34_00615) | ccrA | 112131..113477 (-) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 448 a.a. Molecular weight: 52138.19 Da Isoelectric Point: 10.1760
>NTDB_id=561723 KFV34_RS00615 WP_000816499.1 112131..113477(-) (ccrA) [Staphylococcus epidermidis strain B1282731]
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
MKRAIGYLRQSTTKQQSLPAQKQAIELLAPKHNIQNIQYISDKQSGRTDNRTGYQQVTERIQQRQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFMSLAELESDNIGEQVKNGLREKAKQGKLITTHAPFGYHYQ
NGTFIINNDESPTVKAVFNYYLQGYGYKKIAQYLEDDNKLITRKPYQVRNIIMNPNYCGRVINQYGQYNNMVPPIVSATK
YEHAQAIRNKKQLHCIPSENQLKQKIKCPCCDSTLTNMTIRKKHTLRYYICPKNMNESRFVCSFKGINAQKLEVQVLATC
QNFFQNQQLYSKINNAIHQRLKKQRVIEAKSTLTQEQLIDKLAKGMIDAESFRKQTHLMNQKHKTISSISDNQLQTSLQK
VIQKSFTLNMLHPYIDEIRITKNKALVGIYFKNEPLNIVNQTSQSSIA
Nucleotide
Download Length: 1347 bp
>NTDB_id=561723 KFV34_RS00615 WP_000816499.1 112131..113477(-) (ccrA) [Staphylococcus epidermidis strain B1282731]
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
ATGAAACGAGCCATTGGTTATTTGCGCCAAAGTACAACGAAACAACAATCACTCCCAGCTCAAAAGCAAGCAATAGAATT
ATTAGCTCCAAAGCACAATATTCAAAATATCCAATACATTAGTGATAAGCAATCAGGCAGAACAGATAATCGAACAGGCT
ATCAACAAGTCACCGAACGCATCCAACAAAGACAATGTGACGTATTATGTTGTTATCGCTTGAATCGACTTCATCGCAAC
TTGAAAAATGCATTAAAACTCATGAAACTCTGTCAAAAATATCATGTTCATATTCTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCGTTTGATCGCCTAAAACTCAATATATTCATGAGTCTGGCTGAACTTGAATCCGATAATATTGGAGAAC
AAGTCAAAAATGGACTTAGAGAAAAGGCAAAACAAGGTAAACTCATAACGACCCATGCGCCTTTCGGTTATCACTATCAA
AATGGTACTTTCATCATTAATAATGATGAATCACCTACCGTCAAAGCTGTATTCAATTATTATCTTCAAGGATATGGCTA
CAAGAAGATTGCACAATATTTAGAAGACGATAATAAACTTATTACCCGCAAGCCTTATCAGGTACGAAATATAATTATGA
ACCCAAATTATTGTGGTCGTGTCATCAATCAATATGGTCAATATAACAATATGGTACCACCTATTGTTTCGGCAACGAAA
TATGAACATGCTCAAGCAATCCGTAATAAGAAGCAACTTCACTGTATACCTTCAGAGAATCAGCTGAAACAAAAGATCAA
ATGTCCTTGTTGTGACTCAACACTGACAAATATGACAATAAGAAAAAAACATACATTGCGATATTATATTTGTCCTAAAA
ATATGAATGAATCTCGCTTTGTCTGTTCATTCAAAGGAATAAATGCACAAAAATTAGAAGTTCAAGTCTTAGCTACATGT
CAGAACTTCTTTCAAAACCAACAGCTCTATTCAAAAATTAATAATGCAATTCATCAACGCCTCAAAAAACAAAGAGTGAT
AGAAGCTAAAAGTACGCTAACTCAAGAACAACTGATAGATAAACTTGCCAAAGGTATGATTGATGCTGAATCATTCAGAA
AACAGACTCATTTGATGAATCAAAAGCACAAAACCATATCCTCCATAAGTGATAATCAGTTACAAACATCACTACAAAAG
GTTATACAGAAAAGTTTCACGTTAAACATGCTGCATCCCTATATTGATGAAATTCGCATTACAAAAAATAAAGCCCTTGT
TGGGATCTATTTCAAAAATGAACCATTGAACATTGTGAACCAAACCTCGCAATCATCGATTGCTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
78.174 |
100 |
0.783 |
| ccrA | Staphylococcus aureus N315 |
72.383 |
100 |
0.725 |