Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | KFV51_RS00365 | Genome accession | NZ_CP073869 |
| Coordinates | 66439..67800 (-) | Length | 453 a.a. |
| NCBI ID | WP_001631036.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain B1279591 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 64814..113475 | 66439..67800 | within | 0 |
Gene organization within MGE regions
Location: 64814..113475
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFV51_RS00360 (KFV51_00360) | ccrB | 64814..66442 (-) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| KFV51_RS00365 (KFV51_00365) | ccrA | 66439..67800 (-) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| KFV51_RS00370 (KFV51_00370) | - | 67987..68616 (-) | 630 | Protein_55 | hypothetical protein | - |
| KFV51_RS00375 (KFV51_00375) | - | 68625..68963 (+) | 339 | Protein_56 | recombinase family protein | - |
| KFV51_RS00380 (KFV51_00380) | - | 69075..69434 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| KFV51_RS00385 (KFV51_00385) | - | 69641..69967 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV51_RS00390 (KFV51_00390) | - | 70297..72222 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| KFV51_RS00395 (KFV51_00395) | - | 73474..73779 (+) | 306 | WP_000677987.1 | hypothetical protein | - |
| KFV51_RS00400 (KFV51_00400) | - | 73977..74840 (+) | 864 | WP_000680579.1 | hypothetical protein | - |
| KFV51_RS00405 (KFV51_00405) | - | 74948..76423 (+) | 1476 | WP_001138664.1 | DUF6038 family protein | - |
| KFV51_RS00410 (KFV51_00410) | - | 76650..77750 (+) | 1101 | WP_000449985.1 | DNA polymerase | - |
| KFV51_RS00415 (KFV51_00415) | - | 77743..78114 (+) | 372 | WP_001058157.1 | hypothetical protein | - |
| KFV51_RS00420 (KFV51_00420) | - | 78111..79754 (+) | 1644 | WP_012086574.1 | DUF5906 domain-containing protein | - |
| KFV51_RS00425 (KFV51_00425) | - | 79981..81657 (+) | 1677 | WP_012086571.1 | recombinase family protein | - |
| KFV51_RS00430 (KFV51_00430) | - | 81763..82101 (+) | 339 | WP_012086569.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV51_RS00435 (KFV51_00435) | - | 82197..82508 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| KFV51_RS00440 (KFV51_00440) | - | 82524..83030 (+) | 507 | WP_012086564.1 | DUF1643 domain-containing protein | - |
| KFV51_RS00445 (KFV51_00445) | - | 83058..83504 (+) | 447 | WP_012086562.1 | JAB domain-containing protein | - |
| KFV51_RS00450 (KFV51_00450) | - | 83674..84546 (+) | 873 | WP_012086560.1 | HTH domain-containing protein | - |
| KFV51_RS00455 (KFV51_00455) | - | 84598..84888 (+) | 291 | WP_012086558.1 | hypothetical protein | - |
| KFV51_RS00465 (KFV51_00465) | - | 85111..85266 (+) | 156 | Protein_73 | metal-sensing transcriptional repressor | - |
| KFV51_RS00470 (KFV51_00470) | - | 85263..86021 (+) | 759 | WP_000623679.1 | sulfite exporter TauE/SafE family protein | - |
| KFV51_RS00475 (KFV51_00475) | - | 86191..86400 (+) | 210 | Protein_75 | heavy metal translocating P-type ATPase | - |
| KFV51_RS00480 (KFV51_00480) | - | 86418..86963 (+) | 546 | WP_031869236.1 | YdhK family protein | - |
| KFV51_RS00485 (KFV51_00485) | - | 87406..88662 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| KFV51_RS00490 (KFV51_00490) | - | 89107..89781 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KFV51_RS00495 (KFV51_00495) | - | 89865..90206 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| KFV51_RS00500 (KFV51_00500) | - | 91003..91746 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KFV51_RS00505 (KFV51_00505) | - | 91843..92271 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KFV51_RS00510 (KFV51_00510) | mecA | 92317..94326 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KFV51_RS00515 (KFV51_00515) | mecR1 | 94423..96180 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KFV51_RS00520 (KFV51_00520) | mecI | 96180..96551 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KFV51_RS00525 (KFV51_00525) | psm-mec | 96636..96704 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KFV51_RS00530 (KFV51_00530) | - | 97038..98168 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| KFV51_RS00535 (KFV51_00535) | cstB | 98282..99616 (-) | 1335 | Protein_87 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KFV51_RS00540 (KFV51_00540) | - | 99649..100713 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KFV51_RS00545 (KFV51_00545) | cstR | 100849..101109 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KFV51_RS00550 (KFV51_00550) | - | 101109..101747 (+) | 639 | Protein_90 | sulfite exporter TauE/SafE family protein | - |
| KFV51_RS00560 (KFV51_00560) | - | 102021..102637 (-) | 617 | Protein_91 | CadD family cadmium resistance transporter | - |
| KFV51_RS00565 (KFV51_00565) | - | 102718..105132 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| KFV51_RS00570 (KFV51_00570) | - | 105125..105490 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV51_RS00575 (KFV51_00575) | - | 105728..106105 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| KFV51_RS00580 (KFV51_00580) | - | 106112..108004 (-) | 1893 | WP_002485298.1 | site-specific integrase | - |
| KFV51_RS00585 (KFV51_00585) | - | 108199..108522 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| KFV51_RS00590 (KFV51_00590) | - | 108515..108721 (-) | 207 | WP_001077283.1 | hypothetical protein | - |
| KFV51_RS00595 (KFV51_00595) | - | 108723..109244 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| KFV51_RS00600 (KFV51_00600) | - | 109263..109574 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| KFV51_RS00605 (KFV51_00605) | - | 109659..110009 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV51_RS00610 (KFV51_00610) | ccrB | 110480..112108 (-) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| KFV51_RS00615 (KFV51_00615) | ccrA | 112129..113475 (-) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 53316.45 Da Isoelectric Point: 9.8596
>NTDB_id=561683 KFV51_RS00365 WP_001631036.1 66439..67800(-) (ccrA) [Staphylococcus epidermidis strain B1279591]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
Nucleotide
Download Length: 1362 bp
>NTDB_id=561683 KFV51_RS00365 WP_001631036.1 66439..67800(-) (ccrA) [Staphylococcus epidermidis strain B1279591]
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
54.628 |
97.792 |
0.534 |
| ccrA | Staphylococcus aureus N315 |
50.564 |
97.792 |
0.494 |