Detailed information NTG0561657

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV35_RS06010
• Genome accession: NZ_CP073865
• Coordinates: 1195148..1196194 (+)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain B1276912
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1190148..1201194

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV35_RS05985 (KFV35_06025)	-	1191289..1191825 (+)	537	WP_002470337.1	hypothetical protein	-
KFV35_RS05990 (KFV35_06030)	-	1191976..1192962 (-)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV35_RS05995 (KFV35_06035)	map	1193136..1193891 (+)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV35_RS06000 (KFV35_06040)	-	1194049..1194435 (+)	387	WP_001830382.1	hypothetical protein	-
KFV35_RS06005 (KFV35_06045)	liaF	1194450..1195151 (+)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV35_RS06010 (KFV35_06050)	vraS	1195148..1196194 (+)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV35_RS06015 (KFV35_06055)	vraR	1196184..1196813 (+)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV35_RS06020 (KFV35_06060)	-	1196870..1198048 (-)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV35_RS06025 (KFV35_06065)	-	1198455..1198739 (-)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV35_RS06030 (KFV35_06070)	-	1198747..1199211 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV35_RS06035 (KFV35_06075)	-	1199352..1199567 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV35_RS06040 (KFV35_06080)	-	1199569..1200810 (+)	1242	WP_001832467.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561657 KFV35_RS06010 WP_001830374.1 1195148..1196194(+) (vraS) [Staphylococcus epidermidis strain B1276912]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561657 KFV35_RS06010 WP_001830374.1 1195148..1196194(+) (vraS) [Staphylococcus epidermidis strain B1276912]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92