Detailed information NTG0561517

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: KFV47_RS08290
• Genome accession: NZ_CP073857
• Coordinates: 1765878..1766924 (-)
• Length: 348 a.a.
• NCBI ID: WP_001830374.1
• Uniprot ID: A0A0N1EGU4
• Organism: Staphylococcus epidermidis strain B1272014
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1760878..1771924

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KFV47_RS08260 (KFV47_08270)	-	1761262..1762503 (-)	1242	WP_001832467.1	aminopeptidase	-
KFV47_RS08265 (KFV47_08275)	-	1762505..1762720 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
KFV47_RS08270 (KFV47_08280)	-	1762861..1763325 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
KFV47_RS08275 (KFV47_08285)	-	1763333..1763617 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
KFV47_RS08280 (KFV47_08290)	-	1764024..1765202 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
KFV47_RS08285 (KFV47_08295)	vraR	1765259..1765888 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
KFV47_RS08290 (KFV47_08300)	vraS	1765878..1766924 (-)	1047	WP_001830374.1	sensor histidine kinase	Regulator
KFV47_RS08295 (KFV47_08305)	liaF	1766921..1767622 (-)	702	WP_001830436.1	cell wall-active antibiotics response protein LiaF	-
KFV47_RS08300 (KFV47_08310)	-	1767637..1768023 (-)	387	WP_001830382.1	hypothetical protein	-
KFV47_RS08305 (KFV47_08315)	map	1768181..1768936 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
KFV47_RS08310 (KFV47_08320)	-	1769110..1770096 (+)	987	WP_001830388.1	aromatic acid exporter family protein	-
KFV47_RS08315 (KFV47_08325)	-	1770247..1770783 (-)	537	WP_002470337.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40066.49 Da
• Isoelectric Point: 5.8512

>NTDB_id=561517 KFV47_RS08290 WP_001830374.1 1765878..1766924(-) (vraS) [Staphylococcus epidermidis strain B1272014]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=561517 KFV47_RS08290 WP_001830374.1 1765878..1766924(-) (vraS) [Staphylococcus epidermidis strain B1272014]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GGTTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0N1EGU4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	93.023	98.851	0.92