Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | KFV47_RS00280 | Genome accession | NZ_CP073857 |
| Coordinates | 63938..65299 (-) | Length | 453 a.a. |
| NCBI ID | WP_001631036.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain B1272014 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 62313..110974 | 63938..65299 | within | 0 |
Gene organization within MGE regions
Location: 62313..110974
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFV47_RS00275 (KFV47_00275) | ccrB | 62313..63941 (-) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| KFV47_RS00280 (KFV47_00280) | ccrA | 63938..65299 (-) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| KFV47_RS00285 (KFV47_00285) | - | 65486..66115 (-) | 630 | Protein_54 | hypothetical protein | - |
| KFV47_RS00290 (KFV47_00290) | - | 66124..66462 (+) | 339 | Protein_55 | recombinase family protein | - |
| KFV47_RS00295 (KFV47_00295) | - | 66574..66933 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| KFV47_RS00300 (KFV47_00300) | - | 67140..67466 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV47_RS00305 (KFV47_00305) | - | 67796..69721 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| KFV47_RS00310 (KFV47_00310) | - | 70973..71278 (+) | 306 | WP_000677987.1 | hypothetical protein | - |
| KFV47_RS00315 (KFV47_00315) | - | 71476..72339 (+) | 864 | WP_000680579.1 | hypothetical protein | - |
| KFV47_RS00320 (KFV47_00320) | - | 72447..73922 (+) | 1476 | WP_001138664.1 | DUF6038 family protein | - |
| KFV47_RS00325 (KFV47_00325) | - | 74149..75249 (+) | 1101 | WP_000449985.1 | DNA polymerase | - |
| KFV47_RS00330 (KFV47_00330) | - | 75242..75613 (+) | 372 | WP_001058157.1 | hypothetical protein | - |
| KFV47_RS00335 (KFV47_00335) | - | 75610..77253 (+) | 1644 | WP_012086574.1 | DUF5906 domain-containing protein | - |
| KFV47_RS00340 (KFV47_00340) | - | 77480..79156 (+) | 1677 | WP_012086571.1 | recombinase family protein | - |
| KFV47_RS00345 (KFV47_00345) | - | 79262..79600 (+) | 339 | WP_012086569.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV47_RS00350 (KFV47_00350) | - | 79696..80007 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| KFV47_RS00355 (KFV47_00355) | - | 80023..80529 (+) | 507 | WP_012086564.1 | DUF1643 domain-containing protein | - |
| KFV47_RS00360 (KFV47_00360) | - | 80557..81003 (+) | 447 | WP_012086562.1 | JAB domain-containing protein | - |
| KFV47_RS00365 (KFV47_00365) | - | 81173..82045 (+) | 873 | WP_012086560.1 | HTH domain-containing protein | - |
| KFV47_RS00370 (KFV47_00370) | - | 82097..82387 (+) | 291 | WP_012086558.1 | hypothetical protein | - |
| KFV47_RS00380 (KFV47_00380) | - | 82610..82765 (+) | 156 | Protein_72 | metal-sensing transcriptional repressor | - |
| KFV47_RS00385 (KFV47_00385) | - | 82762..83520 (+) | 759 | WP_000623679.1 | sulfite exporter TauE/SafE family protein | - |
| KFV47_RS00390 (KFV47_00390) | - | 83690..83899 (+) | 210 | Protein_74 | heavy metal translocating P-type ATPase | - |
| KFV47_RS00395 (KFV47_00395) | - | 83917..84462 (+) | 546 | WP_031869236.1 | YdhK family protein | - |
| KFV47_RS00400 (KFV47_00400) | - | 84905..86161 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| KFV47_RS00405 (KFV47_00405) | - | 86606..87280 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KFV47_RS00410 (KFV47_00410) | - | 87364..87705 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| KFV47_RS00415 (KFV47_00415) | - | 88502..89245 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KFV47_RS00420 (KFV47_00420) | - | 89342..89770 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KFV47_RS00425 (KFV47_00425) | mecA | 89816..91825 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KFV47_RS00430 (KFV47_00430) | mecR1 | 91922..93679 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KFV47_RS00435 (KFV47_00435) | mecI | 93679..94050 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KFV47_RS00440 (KFV47_00440) | psm-mec | 94135..94203 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KFV47_RS00445 (KFV47_00445) | - | 94558..95667 (+) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| KFV47_RS00450 (KFV47_00450) | cstB | 95781..97115 (-) | 1335 | Protein_86 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KFV47_RS00455 (KFV47_00455) | - | 97148..98212 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KFV47_RS00460 (KFV47_00460) | cstR | 98348..98608 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KFV47_RS00465 (KFV47_00465) | - | 98608..99246 (+) | 639 | Protein_89 | sulfite exporter TauE/SafE family protein | - |
| KFV47_RS00475 (KFV47_00475) | - | 99520..100136 (-) | 617 | Protein_90 | CadD family cadmium resistance transporter | - |
| KFV47_RS00480 (KFV47_00480) | - | 100217..102631 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| KFV47_RS00485 (KFV47_00485) | - | 102624..102989 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV47_RS00490 (KFV47_00490) | - | 103227..103604 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| KFV47_RS00495 (KFV47_00495) | - | 103611..105503 (-) | 1893 | WP_002485298.1 | site-specific integrase | - |
| KFV47_RS00500 (KFV47_00500) | - | 105698..106021 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| KFV47_RS00505 (KFV47_00505) | - | 106014..106220 (-) | 207 | WP_001077283.1 | hypothetical protein | - |
| KFV47_RS00510 (KFV47_00510) | - | 106222..106743 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| KFV47_RS00515 (KFV47_00515) | - | 106762..107073 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| KFV47_RS00520 (KFV47_00520) | - | 107158..107508 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV47_RS00525 (KFV47_00525) | ccrB | 107979..109607 (-) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| KFV47_RS00530 (KFV47_00530) | ccrA | 109628..110974 (-) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 53316.45 Da Isoelectric Point: 9.8596
>NTDB_id=561492 KFV47_RS00280 WP_001631036.1 63938..65299(-) (ccrA) [Staphylococcus epidermidis strain B1272014]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
Nucleotide
Download Length: 1362 bp
>NTDB_id=561492 KFV47_RS00280 WP_001631036.1 63938..65299(-) (ccrA) [Staphylococcus epidermidis strain B1272014]
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
54.628 |
97.792 |
0.534 |
| ccrA | Staphylococcus aureus N315 |
50.564 |
97.792 |
0.494 |