Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   L3X15_RS00350 Genome accession   NZ_CP091423
Coordinates   61115..63052 (+) Length   645 a.a.
NCBI ID   WP_012774891.1    Uniprot ID   -
Organism   Streptococcus suis strain LSM29     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 56115..68052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L3X15_RS00335 (L3X15_00335) - 56985..57923 (-) 939 WP_011921674.1 IS4 family transposase -
  L3X15_RS00340 (L3X15_00340) - 58063..59283 (+) 1221 WP_012774890.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  L3X15_RS00345 (L3X15_00345) - 59474..60997 (+) 1524 WP_011921677.1 Heme/copper-type cytochrome/quinol oxidase subunit 1 -
  L3X15_RS00350 (L3X15_00350) hexB 61115..63052 (+) 1938 WP_012774891.1 DNA mismatch repair endonuclease MutL Machinery gene
  L3X15_RS00355 (L3X15_00355) ruvA 63091..63681 (+) 591 WP_011921679.1 Holliday junction branch migration protein RuvA Machinery gene
  L3X15_RS00360 (L3X15_00360) - 64406..64975 (+) 570 WP_237374705.1 DNA-3-methyladenine glycosylase I -
  L3X15_RS00365 (L3X15_00365) cinA 65012..66193 (+) 1182 WP_012774894.1 competence/damage-inducible protein A Machinery gene
  L3X15_RS00370 (L3X15_00370) recA 66245..67396 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  L3X15_RS00375 (L3X15_00375) spx 67632..68030 (+) 399 WP_002939362.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72995.17 Da        Isoelectric Point: 5.1152

>NTDB_id=561187 L3X15_RS00350 WP_012774891.1 61115..63052(+) (hexB) [Streptococcus suis strain LSM29]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFVLVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENR
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGSNQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=561187 L3X15_RS00350 WP_012774891.1 61115..63052(+) (hexB) [Streptococcus suis strain LSM29]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTCAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCCCTGCCCTCCATTGCTTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAT
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCCTT
TGTCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTTATCAACGGTCGCTATATCAAGAATTTTTTGCTTAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGCTGGCAGTCATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCACTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAGA
CCTACATCTGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGTGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCACAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAAGTTGACAATTCAGCTCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGATGCCCTTCGTCAAGTTGGTGTCAACTTGGAAGAATATGGATCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGCATTTATGAGATGTGCGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCCATCATGATGTCTTGTAAACGGTCAATCAAGGCCAATCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAATTGCCCGCACGGCC
GCCCAGTCTTAGTGCATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGT
GAATTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(447-589)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.462

100

0.73