Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | KFV36_RS00285 | Genome accession | NZ_CP073827 |
| Coordinates | 64965..66326 (-) | Length | 453 a.a. |
| NCBI ID | WP_001631036.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain B1208538 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 63340..112001 | 64965..66326 | within | 0 |
Gene organization within MGE regions
Location: 63340..112001
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFV36_RS00280 (KFV36_00280) | ccrB | 63340..64968 (-) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
| KFV36_RS00285 (KFV36_00285) | ccrA | 64965..66326 (-) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| KFV36_RS00290 (KFV36_00290) | - | 66513..67142 (-) | 630 | Protein_57 | hypothetical protein | - |
| KFV36_RS00295 (KFV36_00295) | - | 67151..67489 (+) | 339 | Protein_58 | recombinase family protein | - |
| KFV36_RS00300 (KFV36_00300) | - | 67601..67960 (-) | 360 | WP_001631039.1 | hypothetical protein | - |
| KFV36_RS00305 (KFV36_00305) | - | 68167..68493 (+) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV36_RS00310 (KFV36_00310) | - | 68823..70748 (+) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| KFV36_RS00315 (KFV36_00315) | - | 72000..72305 (+) | 306 | WP_000677987.1 | hypothetical protein | - |
| KFV36_RS00320 (KFV36_00320) | - | 72503..73366 (+) | 864 | WP_000680579.1 | hypothetical protein | - |
| KFV36_RS00325 (KFV36_00325) | - | 73474..74949 (+) | 1476 | WP_001138664.1 | DUF6038 family protein | - |
| KFV36_RS00330 (KFV36_00330) | - | 75176..76276 (+) | 1101 | WP_000449985.1 | DNA polymerase | - |
| KFV36_RS00335 (KFV36_00335) | - | 76269..76640 (+) | 372 | WP_001058157.1 | hypothetical protein | - |
| KFV36_RS00340 (KFV36_00340) | - | 76637..78280 (+) | 1644 | WP_012086574.1 | DUF5906 domain-containing protein | - |
| KFV36_RS00345 (KFV36_00345) | - | 78507..80183 (+) | 1677 | WP_012086571.1 | recombinase family protein | - |
| KFV36_RS00350 (KFV36_00350) | - | 80289..80627 (+) | 339 | WP_012086569.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV36_RS00355 (KFV36_00355) | - | 80723..81034 (+) | 312 | WP_001083109.1 | DUF960 family protein | - |
| KFV36_RS00360 (KFV36_00360) | - | 81050..81556 (+) | 507 | WP_012086564.1 | DUF1643 domain-containing protein | - |
| KFV36_RS00365 (KFV36_00365) | - | 81584..82030 (+) | 447 | WP_012086562.1 | JAB domain-containing protein | - |
| KFV36_RS00370 (KFV36_00370) | - | 82200..83072 (+) | 873 | WP_012086560.1 | HTH domain-containing protein | - |
| KFV36_RS00375 (KFV36_00375) | - | 83124..83414 (+) | 291 | WP_012086558.1 | hypothetical protein | - |
| KFV36_RS00385 (KFV36_00385) | - | 83637..83792 (+) | 156 | Protein_75 | metal-sensing transcriptional repressor | - |
| KFV36_RS00390 (KFV36_00390) | - | 83789..84547 (+) | 759 | WP_000623679.1 | sulfite exporter TauE/SafE family protein | - |
| KFV36_RS00395 (KFV36_00395) | - | 84717..84926 (+) | 210 | Protein_77 | heavy metal translocating P-type ATPase | - |
| KFV36_RS00400 (KFV36_00400) | - | 84944..85489 (+) | 546 | WP_031869236.1 | YdhK family protein | - |
| KFV36_RS00405 (KFV36_00405) | - | 85932..87188 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| KFV36_RS00410 (KFV36_00410) | - | 87633..88307 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| KFV36_RS00415 (KFV36_00415) | - | 88391..88732 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| KFV36_RS00420 (KFV36_00420) | - | 89529..90272 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| KFV36_RS00425 (KFV36_00425) | - | 90369..90797 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| KFV36_RS00430 (KFV36_00430) | mecA | 90843..92852 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| KFV36_RS00435 (KFV36_00435) | mecR1 | 92949..94706 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| KFV36_RS00440 (KFV36_00440) | mecI | 94706..95077 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| KFV36_RS00445 (KFV36_00445) | psm-mec | 95162..95230 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| KFV36_RS00450 (KFV36_00450) | - | 95585..96694 (+) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| KFV36_RS00455 (KFV36_00455) | cstB | 96808..98142 (-) | 1335 | Protein_89 | persulfide dioxygenase-sulfurtransferase CstB | - |
| KFV36_RS00460 (KFV36_00460) | - | 98175..99239 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| KFV36_RS00465 (KFV36_00465) | cstR | 99375..99635 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| KFV36_RS00470 (KFV36_00470) | - | 99635..100273 (+) | 639 | Protein_92 | sulfite exporter TauE/SafE family protein | - |
| KFV36_RS00480 (KFV36_00480) | - | 100547..101163 (-) | 617 | Protein_93 | CadD family cadmium resistance transporter | - |
| KFV36_RS00485 (KFV36_00485) | - | 101244..103658 (-) | 2415 | WP_000378485.1 | cadmium-translocating P-type ATPase CadA | - |
| KFV36_RS00490 (KFV36_00490) | - | 103651..104016 (-) | 366 | WP_000159127.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| KFV36_RS00495 (KFV36_00495) | - | 104254..104631 (-) | 378 | WP_001041908.1 | DUF6262 family protein | - |
| KFV36_RS00500 (KFV36_00500) | - | 104638..106530 (-) | 1893 | WP_002485298.1 | site-specific integrase | - |
| KFV36_RS00505 (KFV36_00505) | - | 106725..107048 (-) | 324 | WP_000088091.1 | JAB domain-containing protein | - |
| KFV36_RS00510 (KFV36_00510) | - | 107041..107247 (-) | 207 | WP_001077283.1 | hypothetical protein | - |
| KFV36_RS00515 (KFV36_00515) | - | 107249..107770 (-) | 522 | WP_000836008.1 | DUF1643 domain-containing protein | - |
| KFV36_RS00520 (KFV36_00520) | - | 107789..108100 (-) | 312 | WP_000833212.1 | DUF960 family protein | - |
| KFV36_RS00525 (KFV36_00525) | - | 108185..108535 (-) | 351 | WP_000171449.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| KFV36_RS00530 (KFV36_00530) | ccrB | 109006..110634 (-) | 1629 | WP_001186596.1 | recombinase family protein | Machinery gene |
| KFV36_RS00535 (KFV36_00535) | ccrA | 110655..112001 (-) | 1347 | WP_000816499.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 53316.45 Da Isoelectric Point: 9.8596
>NTDB_id=561079 KFV36_RS00285 WP_001631036.1 64965..66326(-) (ccrA) [Staphylococcus epidermidis strain B1208538]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI
Nucleotide
Download Length: 1362 bp
>NTDB_id=561079 KFV36_RS00285 WP_001631036.1 64965..66326(-) (ccrA) [Staphylococcus epidermidis strain B1208538]
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
54.628 |
97.792 |
0.534 |
| ccrA | Staphylococcus aureus N315 |
50.564 |
97.792 |
0.494 |