Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   - Genome accession   NC_021900
Coordinates   309280..309324 (+) Length   15 a.a.
NCBI ID   - Uniprot ID   -
Organism   Streptococcus lutetiensis 033     
Function   activate transcription of comX; activate transcription of comS (predicted from homology)   
Competence regulation

Genomic Context


Location: 304280..314324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KE3_RS01630 (KE3_0331) - 304609..305058 (+) 450 WP_020916197.1 DUF523 domain-containing protein -
  KE3_RS01635 (KE3_0332) purE 305058..305546 (+) 489 WP_020916198.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  KE3_RS01640 (KE3_0333) purK 305533..306624 (+) 1092 WP_020916199.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  KE3_RS11080 - 306627..306722 (+) 96 Protein_285 phosphoribosylaminoimidazole carboxylase -
  KE3_RS01645 (KE3_0334) purB 306812..308110 (+) 1299 WP_020916200.1 adenylosuccinate lyase -
  KE3_RS01650 (KE3_0335) comR 308299..309177 (+) 879 WP_173636488.1 helix-turn-helix domain-containing protein Regulator
  - comS 309280..309324 (+) 45 - - Regulator
  KE3_RS01655 (KE3_0337) ruvB 309379..310377 (+) 999 WP_020916203.1 Holliday junction branch migration DNA helicase RuvB -
  KE3_RS10715 (KE3_0338) - 310550..310756 (+) 207 WP_020916204.1 DUF7010 family protein -
  KE3_RS11180 (KE3_0339) - 310716..311081 (+) 366 WP_231853261.1 DUF7010 family protein -
  KE3_RS01665 (KE3_0340) - 311320..311751 (+) 432 WP_014334179.1 low molecular weight protein-tyrosine-phosphatase -
  KE3_RS01670 (KE3_0341) - 311769..312149 (+) 381 WP_006531314.1 membrane protein -
  KE3_RS01675 (KE3_0342) - 312146..313939 (+) 1794 WP_020916207.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 15 a.a.        Molecular weight: 1736.15 Da        Isoelectric Point: 9.1500

>NTDB_id=561 309280..309324(+) (comS) [Streptococcus lutetiensis 033]
MLKGFTVLLTAWWGL

Nucleotide


Download         Length: 45 bp        

>NTDB_id=561 309280..309324(+) (comS) [Streptococcus lutetiensis 033]
ATGTTAAAGGGATTTACGGTTTTATTGACAGCCTGGTGGGGATTG

XIP


This gene is known to encode the precursor of σX inducing peptide (XIP), which involves in competence development. The mature XIP sequence is displayed as below:

LTAWWGL


Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus infantarius subsp. infantarius ATCC BAA-102

100

100

1


Multiple sequence alignment