Detailed information NTG0055825

Bioinformatically predicted

Overview

• Name: pepF
• Type: Regulator
• Locus tag: GHH_RS03800
• Genome accession: NC_020210
• Coordinates: 748531..750354 (+)
• Length: 607 a.a.
• NCBI ID: WP_015374160.1
• Uniprot ID: L7ZX00
• Organism: Geobacillus sp. GHH01
• Function: degradation of XIP; competence shut-off (predicted from homology) Competence regulation

Genomic Context

Location: 743531..755354

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GHH_RS03780 (GHH_c07620)	-	743676..744335 (-)	660	WP_014195176.1	TerC family protein	-
GHH_RS03785 (GHH_c07630)	mecA	744546..745226 (+)	681	WP_015374157.1	adaptor protein MecA	-
GHH_RS03790 (GHH_c07640)	cls	745507..747015 (+)	1509	WP_015374158.1	cardiolipin synthase	-
GHH_RS03795 (GHH_c07650)	-	747203..748531 (+)	1329	WP_015374159.1	competence protein CoiA	-
GHH_RS03800 (GHH_c07660)	pepF	748531..750354 (+)	1824	WP_015374160.1	oligoendopeptidase F	Regulator
GHH_RS03805 (GHH_c07670)	-	750368..750565 (-)	198	WP_015374161.1	hypothetical protein	-
GHH_RS03810 (GHH_c07680)	spxH	750991..751884 (-)	894	WP_015374162.1	ClpXP adapter protein SpxH	-
GHH_RS03815 (GHH_c07690)	-	751877..752290 (-)	414	WP_015374163.1	globin-like protein	-
GHH_RS03820 (GHH_c07700)	-	752393..753016 (-)	624	WP_015374164.1	lytic transglycosylase domain-containing protein	-
GHH_RS03825 (GHH_c07710)	-	753013..753606 (-)	594	WP_011230328.1	CYTH domain-containing protein	-
GHH_RS03830 (GHH_c07720)	-	753742..754119 (+)	378	WP_015374165.1	hypothetical protein	-
GHH_RS03835 (GHH_c07730)	-	754248..754886 (+)	639	WP_011230330.1	GTP pyrophosphokinase family protein	-

Sequence

Protein

• Length: 607 a.a.
• Molecular weight: 70302.44 Da
• Isoelectric Point: 5.0455

>NTDB_id=55825 GHH_RS03800 WP_015374160.1 748531..750354(+) (pepF) [Geobacillus sp. GHH01]
MTVEEKKAKKSLPLRSEIPVEETWRLEDIFPTDDAWEEEFKQVKAMIPKLGEYKGRLGESPEVLYEALKCQDDVSMRLGK
LYTYAHMRYDQDTTNSFYQGLDARAKSLYSEASSAMAFIVPEILAIDEAVLRSFLEQYEPLRLYAHALDEITRQRPHVLS
AEEEAILAQAAEVMQATSDTFSALNNADLTFPTIIDENGEEVEVTHGRFIRFLESTDRRVRRDAFYAVYHTYEKFQNTFA
NTLAGTVKKDNFFARIRRYRSAREAALDANNIPESVYDNLIATIHEHLPLLHRYVRLRKRVLGLDELHMYDLYTPLVQEV
KMEVTYEEAKQYMLEGLAPLGEEYVAIVKEGLDNRWVDVRENKGKRSGAYSSGAYGTHPYILLNWQDNVNNLFTLVHEFG
HSVHSYYTRKTQPYPYAHYSIFVAEVASTCNEALLNDYLLKTIDDEKKRLYLLNHYLEGFRGTVFRQTMFAEFEHLIHLK
AQQGEALTAETLTSLYYDLNKTYFGDDIVVDKEIGLEWARIPHFYYNYYVYQYATGFSAATALSKQILEEGEPAVRRYID
FLKAGSSDYPIEVLKKAGVDMTSAEPIRQACQVFAEKLDEMERLLEK

Nucleotide

• Length: 1824 bp

>NTDB_id=55825 GHH_RS03800 WP_015374160.1 748531..750354(+) (pepF) [Geobacillus sp. GHH01]
ATGACGGTGGAGGAAAAGAAAGCGAAAAAGTCGCTGCCGCTGCGAAGCGAGATTCCGGTGGAAGAAACGTGGCGGCTTGA
GGACATTTTTCCCACCGATGACGCCTGGGAAGAAGAGTTCAAACAAGTGAAGGCGATGATTCCAAAGCTTGGCGAATACA
AAGGGCGGCTTGGCGAATCGCCGGAAGTGTTGTATGAAGCGCTGAAATGCCAAGATGACGTATCGATGCGCCTCGGCAAG
CTGTATACATACGCCCATATGCGCTATGATCAAGATACGACCAACTCGTTTTACCAAGGGCTCGACGCCCGGGCGAAAAG
CTTGTACAGCGAAGCATCGAGCGCGATGGCGTTTATCGTGCCGGAAATTTTGGCGATCGATGAAGCGGTGCTGCGCTCGT
TTTTGGAACAATACGAGCCGCTTCGCTTGTATGCGCACGCGTTAGACGAAATTACGCGCCAGCGCCCGCACGTGCTGTCG
GCGGAAGAGGAGGCGATCTTGGCGCAGGCAGCCGAGGTGATGCAGGCGACATCCGACACGTTCAGCGCGTTGAACAACGC
TGATTTGACGTTTCCGACGATCATCGATGAAAACGGCGAGGAAGTCGAAGTCACGCACGGCCGGTTCATCCGCTTTTTAG
AAAGCACGGACCGCCGCGTCCGCCGCGATGCGTTTTACGCCGTATACCATACGTATGAGAAGTTTCAAAATACGTTCGCC
AATACGCTTGCCGGCACGGTGAAAAAAGACAACTTTTTCGCCCGCATCCGCCGCTACCGTTCGGCGCGGGAAGCGGCGTT
GGATGCGAACAACATTCCGGAGAGCGTCTATGACAACTTAATTGCTACGATTCATGAACATTTGCCATTGCTGCACCGGT
ATGTGCGGCTGCGCAAACGAGTGCTTGGGCTTGATGAGCTGCATATGTACGACTTGTACACGCCGCTTGTGCAAGAAGTG
AAAATGGAAGTGACGTACGAGGAAGCGAAGCAATATATGCTTGAAGGGCTCGCGCCGCTTGGCGAGGAATATGTGGCGAT
CGTAAAAGAGGGGCTTGACAACCGTTGGGTCGATGTGCGCGAAAACAAAGGAAAGCGAAGTGGCGCCTATTCGTCGGGAG
CGTACGGCACCCATCCGTACATTTTGCTCAACTGGCAGGACAATGTGAACAATTTGTTTACACTTGTGCATGAATTTGGC
CATTCGGTGCACAGCTACTATACGCGCAAAACGCAGCCGTATCCGTATGCGCATTATTCAATTTTCGTCGCCGAAGTGGC
GTCAACATGCAATGAGGCGCTGTTGAACGACTATTTGCTGAAAACAATCGATGATGAGAAAAAGCGACTCTATTTGCTCA
ACCATTATCTTGAGGGGTTCCGCGGCACGGTTTTTCGCCAGACGATGTTCGCGGAGTTTGAGCATTTGATCCATTTGAAG
GCGCAACAAGGCGAGGCATTGACGGCCGAGACGTTGACGTCCCTTTATTACGACTTAAATAAAACGTATTTTGGCGATGA
TATTGTCGTGGACAAAGAAATCGGCCTCGAGTGGGCGCGCATTCCGCATTTTTATTACAACTACTACGTGTACCAATACG
CAACCGGCTTCAGCGCGGCGACTGCACTTAGCAAACAAATTTTGGAAGAAGGCGAACCGGCGGTGAGACGGTACATCGAC
TTTTTAAAAGCCGGCAGTTCTGATTACCCGATTGAAGTATTGAAAAAAGCCGGCGTCGACATGACGAGCGCCGAGCCGAT
CCGCCAAGCGTGCCAAGTGTTTGCGGAGAAGCTTGATGAGATGGAGCGGCTGCTTGAGAAATGA

Domains

Predicted by InterproScan.

• Oligopeptidase F (Peptidase_M3_N) (122-191)

• Peptidase family M3 (Peptidase_M3) (213-592)

3D structure

• AlphaFold DB: L7ZX00

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pepF	Streptococcus salivarius strain HSISS4	51.433	97.694	0.502