Detailed information NTG0557866

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: INT76_RS09490
• Genome accession: NZ_CP073084
• Coordinates: 1884697..1886793 (+)
• Length: 698 a.a.
• NCBI ID: WP_212570212.1
• Uniprot ID: -
• Organism: Streptococcus oriscaviae strain HKU75
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1879697..1891793

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INT76_RS09460 (INT76_09460)	rhaD	1880002..1880817 (+)	816	WP_212573059.1	rhamnulose-1-phosphate aldolase	-
INT76_RS09465 (INT76_09465)	-	1881089..1881694 (+)	606	WP_212570202.1	DUF1349 domain-containing protein	-
INT76_RS11190 (INT76_09470)	-	1881779..1881904 (+)	126	WP_212570204.1	helix-turn-helix transcriptional regulator	-
INT76_RS09475 (INT76_09475)	-	1882023..1882289 (+)	267	WP_212570206.1	ACT domain-containing protein	-
INT76_RS09480 (INT76_09480)	-	1882301..1883638 (+)	1338	WP_212570208.1	PFL family protein	-
INT76_RS09485 (INT76_09485)	-	1883706..1884398 (+)	693	WP_212570210.1	histidine phosphatase family protein	-
INT76_RS09490 (INT76_09490)	clpC	1884697..1886793 (+)	2097	WP_212570212.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
INT76_RS09495 (INT76_09495)	-	1886850..1889183 (-)	2334	WP_212570214.1	Cna B-type domain-containing protein	-
INT76_RS09500 (INT76_09500)	malQ	1889487..1890995 (+)	1509	WP_249116147.1	4-alpha-glucanotransferase	-

Sequence

Protein

• Length: 698 a.a.
• Molecular weight: 77024.97 Da
• Isoelectric Point: 4.9385

>NTDB_id=557866 INT76_RS09490 WP_212570212.1 1884697..1886793(+) (clpC) [Streptococcus oriscaviae strain HKU75]
MNNNFNNFNNMDDIFNQLMGNMGGYNTERRRYSINGREVTPEEFVYYRQTGKLPQSEQAQTQETKGNVKPGGILAKLGRN
LTEDAREGKLDPVIGRNKEIQETAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGAFEENIQNLVDEVKKAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTLIGATTQDEYRNTIMK
NAALARRFNEVKVNAPSSEDTYQILKGIKPLYEAHHNIDLPDSVLKAAVDYSVQYIPQRSLPDKAIDLIDVTAAHLAAQH
SVTDIKTLEEEIAQARNRQTQAAEKEDYEQALKEKVRIDKLQAQIDNHTESQRVVATVNDVAEAVERMTGIPVSQMGASD
IERLKEMKSRLAANVIGQDDAVEAVSRAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKEAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGHLTDGQGNTVNFKNTVI
IATSNAGFGYPATAEGDGDIMERIAPYFRPEFLNRFNAVIEFKHLDKEDLKAIVDLMLAQVNKTLAKKEIELKVTEAAKA
YLMEEGYDKAMGARPLRRVIESQIRDKVTDFYLDNIHAKRLVADMVDGQLVIQEELGN

Nucleotide

• Length: 2097 bp

>NTDB_id=557866 INT76_RS09490 WP_212570212.1 1884697..1886793(+) (clpC) [Streptococcus oriscaviae strain HKU75]
ATGAACAATAATTTCAACAACTTTAACAATATGGACGACATTTTCAACCAACTTATGGGAAATATGGGCGGCTACAATAC
GGAACGCAGACGCTATTCTATCAATGGCCGCGAAGTGACACCAGAAGAGTTTGTCTACTATCGCCAAACAGGTAAGCTCC
CACAGAGCGAGCAAGCCCAAACGCAGGAAACTAAAGGAAATGTCAAGCCAGGTGGTATTTTGGCTAAATTGGGTCGCAAT
CTGACAGAGGATGCCCGTGAAGGCAAGTTGGATCCAGTCATTGGTCGGAATAAGGAAATTCAAGAAACCGCCGAAATTCT
AGCCCGTCGTACCAAGAACAATCCTGTTCTGGTTGGAGATGCGGGTGTCGGAAAAACCGCCGTAGTAGAAGGTCTGGCTC
AAGCCATTGTCAACGGTGATGTTCCAGCTGCTATCAAAAACAAGGAAATTATCTCTATTGATATTTCAGGTTTGGAGGCC
GGAACCCAATACCGCGGTGCTTTTGAAGAAAACATCCAAAATTTGGTCGATGAGGTCAAAAAAGCAGGCAACATCATCCT
CTTCTTTGATGAAATTCATCAGATTTTGGGTGCAGGTAGTACAGGAGGGGATTCAGGTTCCAAAGGTCTGGCGGATATTT
TGAAACCAGCACTTTCCCGCGGAGAATTAACCCTAATCGGGGCAACAACACAGGATGAGTATCGGAACACCATCATGAAA
AATGCAGCTCTAGCGCGCCGCTTCAATGAAGTCAAGGTTAATGCTCCATCTTCTGAGGATACCTACCAGATTCTCAAGGG
GATCAAACCTCTCTATGAGGCTCACCACAATATCGACCTTCCAGATTCTGTATTGAAGGCAGCGGTGGATTACTCGGTTC
AATACATTCCTCAACGCAGTTTGCCAGACAAGGCCATTGACTTGATTGATGTAACTGCTGCTCACTTGGCAGCTCAGCAC
TCTGTAACAGATATTAAAACGCTTGAAGAAGAAATTGCTCAAGCCCGCAATCGCCAGACTCAGGCTGCTGAAAAAGAAGA
CTATGAACAAGCGCTCAAGGAAAAAGTCCGTATTGATAAGCTGCAAGCGCAGATCGACAACCATACAGAGAGCCAGCGTG
TCGTAGCTACGGTCAACGACGTCGCTGAGGCAGTTGAGCGGATGACAGGGATTCCAGTATCGCAGATGGGGGCATCCGAC
ATTGAGCGCCTCAAGGAGATGAAGTCACGTCTTGCTGCTAATGTCATCGGTCAAGACGATGCGGTTGAAGCTGTATCACG
CGCCATTCGTCGGAATCGTGCTGGTTTTGATGAAGGCAACCGTCCGATTGGCTCCTTCCTCTTTGTCGGCCCGACTGGGG
TTGGGAAGACTGAGCTAGCCAAACAGTTGGCTCTGGATATGTTTGGCTCAAAAGAAGCCATCATCCGTCTGGATATGTCT
GAGTACAGCGACCGAACAGCGGTATCTAAGCTTATTGGAACCACCGCGGGTTATGTGGGCTATGACGACAACTCCAACAC
TTTAACCGAGCGTGTGCGCCGCAATCCGTACTCGATTGTCCTTTTGGATGAAATTGAAAAGGCAGACCCGCAGGTTATTA
CCCTTCTGCTTCAGGTACTAGATGACGGGCATTTGACAGATGGTCAGGGTAACACCGTCAACTTCAAGAACACTGTCATT
ATTGCAACCTCAAACGCAGGTTTTGGTTATCCGGCAACCGCTGAAGGAGATGGTGATATTATGGAGCGGATTGCCCCTTA
CTTCCGTCCAGAATTTCTCAACCGTTTCAACGCAGTCATTGAATTCAAGCACTTGGACAAAGAAGACCTCAAAGCCATCG
TTGATCTCATGTTGGCACAGGTTAACAAGACTTTGGCCAAGAAGGAAATTGAATTGAAGGTAACAGAAGCAGCCAAGGCC
TATCTGATGGAAGAAGGCTACGATAAGGCCATGGGAGCTCGCCCGCTTCGCCGTGTGATAGAGAGTCAGATCCGTGATAA
GGTGACAGATTTCTATCTTGACAACATCCATGCTAAGCGACTTGTAGCAGACATGGTGGATGGACAGCTAGTCATTCAGG
AAGAGCTGGGGAACTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (605-678)

• AAA lid domain (AAA_lid_9) (257-351)

• ATPase family associated with various cellular activities (AAA) (AAA) (116-248)

• AAA domain (Cdc48 subfamily) (AAA_2) (441-598)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	48.222	100	0.486
clpE	Streptococcus mutans UA159	50.157	91.404	0.458
clpE	Streptococcus pneumoniae Rx1	49.92	89.255	0.446
clpE	Streptococcus pneumoniae D39	49.92	89.255	0.446
clpE	Streptococcus pneumoniae R6	49.92	89.255	0.446
clpE	Streptococcus pneumoniae TIGR4	49.92	89.255	0.446
clpC	Bacillus subtilis subsp. subtilis str. 168	45.82	92.55	0.424
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.553	94.269	0.401
clpC	Streptococcus thermophilus LMD-9	43.269	89.398	0.387
clpC	Streptococcus mutans UA159	43.018	89.255	0.384
clpC	Streptococcus thermophilus LMG 18311	42.949	89.398	0.384
clpC	Streptococcus pneumoniae Rx1	43.134	88.682	0.383
clpC	Streptococcus pneumoniae D39	43.134	88.682	0.383
clpC	Streptococcus pneumoniae TIGR4	42.973	88.682	0.381