Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   INT76_RS04185 Genome accession   NZ_CP073084
Coordinates   832427..833476 (-) Length   349 a.a.
NCBI ID   WP_212572496.1    Uniprot ID   -
Organism   Streptococcus oriscaviae strain HKU75     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 827427..838476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  INT76_RS04155 (INT76_04155) - 827791..828438 (+) 648 WP_212572483.1 A24 family peptidase -
  INT76_RS04160 (INT76_04160) trpB 828465..829640 (-) 1176 WP_212572486.1 tryptophan synthase subunit beta -
  INT76_RS04165 (INT76_04165) - 829857..830054 (+) 198 WP_212572488.1 hypothetical protein -
  INT76_RS04170 (INT76_04170) - 830111..830626 (-) 516 WP_212572490.1 VanZ family protein -
  INT76_RS04175 (INT76_04175) rlmN 830623..831735 (-) 1113 WP_212572492.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  INT76_RS04180 (INT76_04180) - 831743..832312 (-) 570 WP_212572494.1 YutD-like domain-containing protein -
  INT76_RS04185 (INT76_04185) sepM 832427..833476 (-) 1050 WP_212572496.1 SepM family pheromone-processing serine protease Regulator
  INT76_RS04190 (INT76_04190) coaD 833463..833951 (-) 489 WP_212572498.1 pantetheine-phosphate adenylyltransferase -
  INT76_RS04195 (INT76_04195) rsmD 833941..834480 (-) 540 WP_212572506.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  INT76_RS04200 (INT76_04200) - 834558..834941 (-) 384 WP_212572508.1 rhodanese-like domain-containing protein -
  INT76_RS04205 (INT76_04205) - 834942..835163 (-) 222 WP_212572510.1 YqgQ family protein -
  INT76_RS04210 (INT76_04210) - 835393..835914 (-) 522 WP_212572512.1 Dps family protein -
  INT76_RS04215 (INT76_04215) - 836145..836351 (+) 207 WP_212572514.1 CsbD family protein -
  INT76_RS04220 (INT76_04220) - 836398..836817 (+) 420 WP_212572516.1 low molecular weight protein-tyrosine-phosphatase -
  INT76_RS04225 (INT76_04225) - 836899..837321 (+) 423 WP_212572518.1 hypothetical protein -

Sequence

Protein


Download         Length: 349 a.a.        Molecular weight: 37927.61 Da        Isoelectric Point: 4.1404

>NTDB_id=557832 INT76_RS04185 WP_212572496.1 832427..833476(-) (sepM) [Streptococcus oriscaviae strain HKU75]
MKKNKKLLLVLSIVGLSALLWLGMFFRLPYYIESPGGAADVRHVLTVNGQEDSEPGSYNFVYVHVQQATAFQLLAAYLNP
TMDIRSEEETTGGANNDDYFRIAQFYMETSQNMAKYQGLTLAGKDVSLDFFGVYVLSLTEDSTFREILNIADTVVSINGE
TFESSADLIKYVSSLELGSSVTVGYISAGQQYEADGSIIKLSNGKNGIGITLVDHTEVDSSVPIEFQTGNIGGPSAGLMF
TLSIYTQLADPDLRDGRIIAGTGTIEQDGSVGDIGGADKKVLSAAQAGATVFFVPNNPVDEKILKENPDAKTNYEEAMEM
VRQEKLDIEVVPVTNVQEAIDYLEKTKSE

Nucleotide


Download         Length: 1050 bp        

>NTDB_id=557832 INT76_RS04185 WP_212572496.1 832427..833476(-) (sepM) [Streptococcus oriscaviae strain HKU75]
ATGAAAAAGAATAAAAAGTTATTACTGGTTCTCTCCATCGTTGGACTCAGTGCCCTTCTCTGGCTGGGAATGTTTTTTCG
ACTTCCCTACTACATTGAAAGCCCTGGTGGAGCAGCAGACGTCCGCCATGTCCTGACGGTCAATGGGCAGGAAGACTCAG
AACCAGGCTCTTATAATTTCGTGTATGTCCATGTCCAGCAAGCCACAGCCTTCCAGCTCTTAGCGGCTTATTTGAATCCG
ACCATGGATATTCGTTCAGAAGAAGAAACAACTGGCGGAGCCAACAATGATGACTACTTCCGGATTGCTCAATTCTATAT
GGAAACTTCGCAAAACATGGCCAAATACCAAGGCTTGACCTTGGCAGGCAAGGATGTGAGTCTGGACTTTTTCGGAGTCT
ATGTTCTCAGCCTAACAGAAGATTCGACCTTCAGAGAAATTCTCAATATAGCAGACACCGTTGTCAGCATCAATGGAGAG
ACCTTTGAAAGCTCAGCAGACCTAATCAAATATGTCAGCAGTTTGGAGCTCGGTAGCAGCGTTACAGTCGGCTACATCAG
TGCTGGCCAACAGTATGAAGCTGATGGAAGCATCATCAAGCTGTCCAATGGCAAGAACGGTATCGGTATCACCCTAGTGG
ATCATACAGAAGTAGACAGCAGTGTTCCCATTGAGTTTCAAACAGGCAACATCGGCGGCCCTAGTGCCGGCCTCATGTTC
ACCCTTTCTATCTACACCCAGTTGGCCGATCCAGACCTACGGGATGGTCGGATAATTGCCGGTACAGGAACCATTGAACA
GGATGGTTCAGTTGGAGATATCGGCGGGGCGGACAAAAAGGTTCTATCGGCTGCTCAGGCTGGTGCCACAGTCTTCTTCG
TTCCCAACAATCCAGTAGATGAGAAGATTCTCAAAGAAAATCCTGATGCCAAGACCAACTACGAAGAAGCCATGGAGATG
GTTCGACAGGAAAAATTAGACATTGAAGTGGTTCCAGTCACCAACGTTCAAGAAGCGATTGATTACTTAGAGAAGACCAA
GAGCGAGTAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(231-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

59.538

99.14

0.59