Detailed information NTG0557606

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: KCG41_RS13325
• Genome accession: NZ_CP073065
• Coordinates: 2677885..2678772 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 17Gst354
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2672885..2683772

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KCG41_RS13295 (KCG41_13300)	-	2672894..2672986 (+)	93	WP_031774855.1	hypothetical protein	-
KCG41_RS13300 (KCG41_13305)	-	2673094..2673591 (-)	498	WP_001065267.1	glutathione peroxidase	-
KCG41_RS13305 (KCG41_13310)	-	2673601..2673861 (-)	261	WP_014937088.1	hypothetical protein	-
KCG41_RS13310 (KCG41_13315)	-	2674243..2674356 (-)	114	WP_014937089.1	hypothetical protein	-
KCG41_RS13315 (KCG41_13320)	-	2675025..2677025 (-)	2001	WP_000776741.1	ABC transporter permease	-
KCG41_RS13320 (KCG41_13325)	-	2677022..2677777 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
KCG41_RS13325 (KCG41_13330)	braS	2677885..2678772 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
KCG41_RS13330 (KCG41_13335)	braR	2678783..2679448 (-)	666	WP_031837700.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
KCG41_RS13335 (KCG41_13340)	-	2679474..2679674 (-)	201	WP_000604731.1	hypothetical protein	-
KCG41_RS13340 (KCG41_13345)	-	2679872..2681296 (+)	1425	WP_021286019.1	alkaline phosphatase	-
KCG41_RS13965	-	2681356..2681457 (-)	102	WP_000731972.1	SE2200 family small protein	-
KCG41_RS13350 (KCG41_13355)	-	2681579..2682034 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
KCG41_RS13355 (KCG41_13360)	-	2682278..2683039 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=557606 KCG41_RS13325 WP_000143420.1 2677885..2678772(-) (braS) [Staphylococcus aureus strain 17Gst354]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=557606 KCG41_RS13325 WP_000143420.1 2677885..2678772(-) (braS) [Staphylococcus aureus strain 17Gst354]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993