Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   L1A18_RS00820 Genome accession   NZ_CP090887
Coordinates   156805..157245 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain NP7536     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 151805..162245
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A18_RS00795 (L1A18_00795) - 152066..153352 (+) 1287 WP_000278868.1 response regulator transcription factor -
  L1A18_RS00800 (L1A18_00800) - 153404..153937 (+) 534 WP_000729030.1 hypothetical protein -
  L1A18_RS00805 (L1A18_00805) nrdI 154015..154485 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  L1A18_RS00810 (L1A18_00810) - 154778..156040 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  L1A18_RS00815 (L1A18_00815) - 156350..156808 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  L1A18_RS00820 (L1A18_00820) brsR 156805..157245 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  L1A18_RS00825 (L1A18_00825) hexB 157601..159550 (+) 1950 WP_000018169.1 DNA mismatch repair endonuclease MutL Machinery gene
  L1A18_RS00830 (L1A18_00830) ribE 159875..160342 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  L1A18_RS00835 (L1A18_00835) - 160343..161548 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  L1A18_RS00840 (L1A18_00840) ribE 161568..162203 (-) 636 WP_000493846.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=556925 L1A18_RS00820 WP_000861956.1 156805..157245(-) (brsR) [Streptococcus pneumoniae strain NP7536]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=556925 L1A18_RS00820 WP_000861956.1 156805..157245(-) (brsR) [Streptococcus pneumoniae strain NP7536]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363