Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   L1A14_RS05540 Genome accession   NZ_CP090883
Coordinates   1077730..1081380 (+) Length   1216 a.a.
NCBI ID   WP_000767245.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LE4448     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1072730..1086380
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A14_RS05515 (L1A14_05515) - 1072855..1073301 (-) 447 WP_044811956.1 tyrosine-type recombinase/integrase -
  L1A14_RS10410 - 1073201..1074029 (-) 829 Protein_1088 IS630 transposase-related protein -
  L1A14_RS05530 (L1A14_05530) - 1074097..1074258 (+) 162 Protein_1089 diacylglycerol kinase family lipid kinase -
  L1A14_RS05535 (L1A14_05535) rexB 1074458..1077733 (+) 3276 WP_000772360.1 ATP-dependent nuclease subunit B Machinery gene
  L1A14_RS05540 (L1A14_05540) rexA 1077730..1081380 (+) 3651 WP_000767245.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  L1A14_RS05545 (L1A14_05545) - 1081342..1081599 (-) 258 WP_144005151.1 hypothetical protein -
  L1A14_RS05550 (L1A14_05550) - 1081820..1082998 (+) 1179 WP_000174775.1 hypothetical protein -

Sequence

Protein


Download         Length: 1216 a.a.        Molecular weight: 140264.00 Da        Isoelectric Point: 5.4445

>NTDB_id=556499 L1A14_RS05540 WP_000767245.1 1077730..1081380(+) (rexA) [Streptococcus pneumoniae strain LE4448]
MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNILVSASAGSGKTFVMAERILDQLARGVEISQLFISTFT
VKAATELKERLEKKISKKIQETDDVELKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNSQKWLSDSFLKGFEKADFTSEKEKLTE
QIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLILDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADL
KPLADAYNEERKTQFTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADISHYTIEILE
NFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNEKFQRYAQNPQEGRLIL
LKENFRSSSEVLSTTNDVFERLMDQEVGEINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMR
LVIKEILKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLDTLRVIHNPLQDYALVA
LMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMASSQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIW
KIYNDRFYYDYVGALPNGPARQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIHKS
KGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIKLSIPSLTYRQNEEELQLASYSEQM
RLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAKNGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTRE
AIGELETKSPLQDSSQADNRQSDTIKEALKMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGVEIAGQGQSVG
KKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLKQVQTSQAVRDKINLDKILAFFDTVLGQEILAN
TDHLYREQPFSMLKRDQKSQEDFVVRGILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIE
KYLILLGKDEAQVVKV

Nucleotide


Download         Length: 3651 bp        

>NTDB_id=556499 L1A14_RS05540 WP_000767245.1 1077730..1081380(+) (rexA) [Streptococcus pneumoniae strain LE4448]
ATGAAGCTTATTCCCTTTTTAAGTGAGGAGGAGATTCAAAAACTGCAAGAAGCAGAAGCAAATTCGAGCAAGGAACAGAA
GAAAACTGCCGAGCAAATCGAAGCTATCTACACTTCTGGCCAGAATATCCTGGTCTCAGCATCGGCTGGTTCTGGAAAGA
CCTTTGTCATGGCAGAGCGCATTCTGGACCAATTGGCGCGTGGTGTCGAAATTTCTCAACTCTTTATCTCAACCTTTACC
GTCAAGGCTGCAACTGAACTTAAAGAACGTTTAGAGAAAAAAATCAGCAAGAAAATCCAAGAAACAGATGATGTCGAGCT
CAAACAACACTTGGGTCGCCAGTTGGCAGACCTACCCAACGCTGCCATCGGAACCATGGACTCTTTCACACAAAAATTCC
TTGGCAAACATGGTTATCTGCTTGATATTGCACCTAATTTCCGTATTTTACAAAACCAAAGCGAGCAACTTCTTCTCGAA
AACGAAGTCTTTCATGAGGTCTTTGAAGCGCATTACCAAGGTAAACAGAAAGAGACCTTTAGTCATTTGCTGAAAAACTT
TGCTGGGCGTGGCAAGGACGAACGGGGTCTGCGCCAGCAGGTCTATAAAATCTATGACTTCCTCCAATCCACCAGCAATT
CTCAAAAGTGGCTGAGTGACTCTTTCCTCAAAGGCTTTGAGAAAGCTGATTTTACCAGTGAAAAAGAAAAACTGACTGAG
CAAATCAAACAAGCCCTTTGGGATTTGGAAAGCTTTTTCCGTTACCATCTGGATAACGATGCCAAGGAGTTTGCAAAGGC
TGCCTATTTAGAAAATGTTCAGTTAATTCTGGATGAAATTTGCTCCCTAAATCAGGAGTCCGATAGTCAGGCTTATCAGG
CAGTGCTTGCGCGTGTTGTCGCCATCTCTAAGGAGAAAAACGGTCGAGCTCTGACTAATGCCAGCCGTAAGGCTGATTTG
AAGCCCCTGGCTGATGCCTACAACGAAGAGAGAAAGACCCAGTTTACTAAACTAGGACAATTATCAGACCAGATAGCGAT
TCTCGACTATCAAGAACGTTATCATGGAGACACTTGGAAACTAGCTAAAACCTTCCAATCTTTCATGAGCGATTTTGTAG
AGGCTTATCGTCAGAGAAAACGACAGGAAAATGCCTTTGAATTCGCTGATATCAGCCATTACACCATTGAGATTTTAGAA
AATTTCCCACAAGTTCGTGAGTCTTATCAGGAGCGCTTCCATGAAGTCATGGTCGATGAGTATCAGGATACCAACCATAT
TCAAGAACGGATGCTGGAATTGTTGTCTAATGGCCACAATCGCTTTATGGTGGGAGATATCAAGCAATCCATCTATCGTT
TCCGTCAGGCAGACCCGCAGATTTTCAATGAGAAATTCCAACGCTATGCGCAAAATCCTCAAGAAGGCAGGCTCATTCTC
CTCAAGGAAAATTTCCGTAGTAGTTCAGAAGTGCTGTCAACAACCAATGATGTCTTTGAACGTCTCATGGACCAAGAGGT
CGGCGAAATCAACTATGATAACATGCACCAGCTTGTTTTTGCCAATACCAAACTGACTCCCAATCCAGACAACAAGGCAG
AATTTCTCCTCTACGACAAGGACGATACAGGTGAGGAAGAAGAGAGTCAAACAGAAACGAAACTAACAGGCGAAATGCGC
TTAGTTATCAAGGAGATTCTGAAACTTCATCAAGAAAAAGGTGTTGCCTTTAAGGAAATTGCCCTTCTGACCTCCAGCCG
CAGTCGTAATGACCAGATTCTCCTCGCCCTGTCTGAGTACGGAATTCCTGTCAAAACTGACGGAGAGCAAAACAATTATC
TCCAATCCCTAGAAGTGCAAGTCATGCTAGACACTCTTCGTGTCATTCACAATCCCCTGCAAGACTACGCCTTGGTTGCC
CTTATGAAGTCTCCAATGTTTGGTTTTGATGAGGATGAGCTAGCACGTTTGTCCCTTCAGAAAGCAGAGGATAAAGTCCA
CGAAAATCTCTATGAGAAACTGGTCAATGCACAAAAAATGGCAAGTAGTCAAAAAGGTTTGATTCACACAGCTCTAGCTG
AAAAACTAAAGCAATTCATGGATATCCTAGCTTCTTGGCGCTTGTATGCCAAAACCCACTCTCTCTATGACTTGATTTGG
AAGATTTACAACGACCGTTTTTATTATGACTATGTTGGGGCTTTGCCGAATGGTCCTGCTAGGCAGGCCAATCTCTATGC
CCTAGCACTGCGTGCTGATCAATTTGAAAAGAGCAATTTCAAAGGTTTGTCGCGTTTTATTCGTATGATTGACCAAGTCT
TAGAAGCCCAGCACGATTTGGCAAGCGTGGCCGTCGCACCGCCAAAAGATGCAGTAGAGCTCATGACCATCCACAAGAGT
AAGGGGCTGGAGTTTCCTTACGTCTTTATCCTCAATATGGATCAAGATTTCAACAAGCAAGACTCTATGTCAGAAGTCAT
TCTCAGTCGTCAGAATGGTCTTGGTGTCAAATATATTGCCAAGATGGAGACAGGGGCAGTAGAAGACCACTATCCTAAAA
CCATCAAACTCTCCATTCCTAGCCTGACCTATAGGCAGAATGAAGAGGAATTACAGCTAGCAAGCTATTCTGAGCAGATG
CGTTTGCTGTATGTTGCTATGACGCGGGCTGAGAAAAAGCTCTATCTTGTCGGCAAGGGTTCTCGTGAAAAGCTGGAAGC
CAAGCAATACCCAGCAGCCAAAAATGGGAAACTAAATAGCAATACTAGACTGCAAGCACGGAATTTCCAAGATTGGCTTT
GGGCTATCAGTAAAGTGTTTACTAAGGACAAGCTCAACTTTAGTTATCGTTTTATTGGCGAAGATCAGTTGACCAGAGAA
GCTATCGGAGAGTTGGAAACCAAGAGTCCTCTCCAAGATAGCTCCCAAGCAGACAATCGTCAGTCAGATACCATCAAAGA
AGCTCTGAAAATGCTGAAGGAGGTGGAAGTTTATAATACTCTTCACCGCGCAGCTATTGAACTTCCTAGTGTTCAAACCC
CAAGTCAAATCAAGAAATTCTACGAACCAGTTATGGATATGGAAGGTGTCGAGATTGCTGGTCAAGGTCAGTCAGTAGGC
AAGAAAATCAGCTTCGATTTGCCAGATTTTTCAACAAAAGAAAAGGTAACTGGAGCTGAGATTGGTAGTGCTACTCACGA
ACTCATGCAGAGAATTGACCTCAGCCAGCAACTAACCCTTGCTAGCCTAACAGAAACACTCAAACAAGTTCAAACTAGCC
AAGCTGTCAGAGACAAGATCAATCTTGATAAAATTCTTGCTTTCTTTGACACAGTACTCGGTCAGGAAATTCTTGCTAAT
ACCGACCATCTCTATCGCGAGCAACCTTTCTCCATGCTCAAACGAGACCAAAAGAGTCAGGAAGACTTTGTTGTCCGTGG
TATCCTTGATGGCTATCTGCTTTACGAAAACAAAATTGTTCTGTTCGACTACAAGACAGACCGCTATGATGAACCAAGTC
AACTCGTAGACCGCTATCGTGGTCAGTTAGCTCTATACGAAGAGGCTTTATCACGAGCCTATTCGATTGAAAATATTGAA
AAATACTTGATTTTACTCGGTAAAGACGAGGCTCAAGTTGTAAAAGTATAA

Domains

Predicted by InterProScan.

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1054-1193)

UvrD-like helicase C-terminal domain (UvrD_C)

(479-896)

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(29-469)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

98.766

100

0.988