Detailed information    

insolico Bioinformatically predicted

Overview

Name   recD/recD2/recDB   Type   Machinery gene
Locus tag   L1A12_RS01785 Genome accession   NZ_CP090882
Coordinates   345401..347767 (-) Length   788 a.a.
NCBI ID   WP_000454482.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain CH2241     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 340401..352767
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  L1A12_RS01760 (L1A12_01760) vraR 340752..341384 (+) 633 WP_000698438.1 response regulator transcription factor Regulator
  L1A12_RS01765 (L1A12_01765) - 341460..342154 (+) 695 Protein_346 DNA alkylation repair protein -
  L1A12_RS01770 (L1A12_01770) - 342613..343215 (+) 603 Protein_347 serine protease -
  L1A12_RS01775 (L1A12_01775) - 343517..343876 (+) 360 WP_000378120.1 tyrosine-type recombinase/integrase -
  L1A12_RS01780 (L1A12_01780) tig 344070..345353 (+) 1284 WP_000116463.1 trigger factor -
  L1A12_RS01785 (L1A12_01785) recD/recD2/recDB 345401..347767 (-) 2367 WP_000454482.1 ATP-dependent RecD-like DNA helicase Machinery gene
  L1A12_RS01790 (L1A12_01790) lepB 347894..348508 (-) 615 WP_001083986.1 signal peptidase I -
  L1A12_RS01795 (L1A12_01795) rnhC 348512..349393 (-) 882 WP_000146855.1 ribonuclease HIII -
  L1A12_RS01800 (L1A12_01800) zapA 349480..349782 (+) 303 WP_000002019.1 cell division protein ZapA -
  L1A12_RS01805 (L1A12_01805) - 349779..350327 (+) 549 WP_000622953.1 CvpA family protein -
  L1A12_RS01810 (L1A12_01810) mutS/mutS2 350431..352767 (+) 2337 WP_001035034.1 endonuclease MutS2 Machinery gene

Sequence

Protein


Download         Length: 788 a.a.        Molecular weight: 88696.57 Da        Isoelectric Point: 4.5836

>NTDB_id=556348 L1A12_RS01785 WP_000454482.1 345401..347767(-) (recD/recD2/recDB) [Streptococcus pneumoniae strain CH2241]
MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVTGTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRA
KPTSKGLVKYFSSSHFKGIGLKTAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMILAKLANY
GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERFRAGLVHSLFQTCMETGDTYVEA
RDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDKVQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKH
ITTVEQELGIEYDNIQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPTGRAARRMN
ELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQLFSNISSNSKILIVGDSDQLPSVSPGQVLAD
LLHIPLIPQTRLEKIYRQSKESTIVTLASQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQV
LAPMYRGTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAITDLIPGKYTESKQDEI
VIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPITSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQ
HIGTARKTYLIERFSDLLENVEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK

Nucleotide


Download         Length: 2367 bp        

>NTDB_id=556348 L1A12_RS01785 WP_000454482.1 345401..347767(-) (recD/recD2/recDB) [Streptococcus pneumoniae strain CH2241]
ATGGAAGTTTATTTTTCAGGAACTATTGAACGGATTATTTTTGAAAATCCCAGCAATTTTTATCGCATCCTCCTCCTAGA
AATCGACGATACGGACGCAGAGGATTTTGATGATTTTGAAATCATTGTCACAGGAACCATGGCTGATGTAATTGAGGGCG
AAGACTATACTTTTTGGGGGCAAATTGTCCAGCACTCCAAGTATGGAGAACAACTGCAAATCAGTCGTTATGATCGCGCA
AAACCAACTAGTAAGGGCTTGGTCAAGTACTTTTCAAGTAGCCATTTCAAGGGGATTGGTCTCAAGACAGCTCAGAAAAT
CGTGGATACCTATGGCGAAAATACCATTGACGAAATTTTGCAACACCCAGAAAAGTTAGAAGGCATCGCAGGACTCTCTG
CCAAAAATCGCGAGGCTTTCGTCTCCACTCTCCGTCTCAACTACGGAACGGAGATGATTTTGGCCAAACTAGCCAACTAC
GGCATTCCCAACAAACTAGCCTTTCAGATTCAAGACTTTTACAAGGAAGAAACCCTTGATGTGGTTGAAAATTATCCCTA
CCAACTGGTTGAGGATATCAAGGGTTTGGGCTTTACCATTGCTGACCAACTAGCTGAGGAACTAGGCATCGAAAGTCAGG
CTCCTGAACGCTTCCGCGCCGGTCTAGTTCACAGTCTTTTTCAGACCTGTATGGAAACAGGGGACACCTATGTTGAAGCA
CGGGATTTGCTGGAACAAACCCTTACTCTCCTTGAGTCTTCCCGTCCCGTGGAACTAGACCCCAGCCAAGTTGCCCAAGA
GCTCTCCTACCTGATCGAAGAAGACAAGGTTCAGCAGATTGATACCAAGATCTTTGACAACAGCCTCTTTTTCGCTGAGG
AAGGTATCCGCAGTCACTTGATTCGTATCCTTGAAAAAGGAAAACAGAAGAGCCAAGATTTAGAAACTATTCAAAAGCAT
ATCACTACTGTCGAGCAAGAACTGGGGATTGAGTATGATAACATTCAAAAACAAGCTATTTGTGACGCTATCCAGAACAA
GGTCTTTATCCTGACAGGTGGGCCTGGTACTGGTAAGACAACTGTTATCAATGGAATCATCGCTGTTTATGCCCTTTTAG
AAGGACTTGACTTCAGGAAGAAAAACAATCTGCCCATTCTTCTTGCTGCTCCAACTGGTCGAGCTGCTCGTCGCATGAAT
GAATTGACAGGTTTGCCTAGCGCGACCATACATCGCCACTTGGGAATGACAGGTGACGATGATACCAGTCATCTGGAAGA
TTACCTAGATGCTGACTTTATCATCGTGGATGAATTCTCTATGGTGGATACTTGGCTGGCCAATCAACTCTTCTCCAATA
TCTCTTCTAACAGTAAGATCCTCATCGTAGGTGACAGTGATCAGCTACCTTCTGTCAGTCCTGGACAGGTTCTAGCGGAT
CTGCTTCATATTCCTTTGATTCCTCAGACTCGCTTGGAAAAAATTTATCGACAAAGCAAAGAATCAACCATCGTCACCCT
AGCTAGTCAGATTCGACAGGGCATCTTGCCAGCTGATTTCACCCAAAAAAAAGCTGACCGTTCCTACTTTGAAATTGCTA
GTGGCCATATTCCTGCCACCATTGAAAAAATCTTAGGTGCCGCCCTCAGAAATGGTATTCCTGCCCGTGATATCCAAGTT
CTGGCTCCTATGTACCGAGGGACGGCAGGGATTGATGCTATCAATCAGCTCATGCAAGACCTGCTCAATCCCCCACAAAA
AGATCAACTCAGTTTTGAAGCTCCTCAGTGCCACTATCGTAAGAGAGACAAGGTCATTCATTTGGTTAACGATGCTGAAA
TCAATGTCTTTAATGGGGATTTAGGAGCTATCACAGACCTGATTCCTGGTAAATACACCGAATCGAAACAAGACGAGATT
GTCATTGATTTTGATGGTAATGAAGTCTCTTACCCCCGTAACGAATGGTACAAGATTCGCTTGGCCTATGCCATGAGTAT
TCATAAGTCTCAGGGAAGTGAGTTCCCAGTTGTCATCCTACCGATTACTAGTGCTAGCCGACGTATGCTGGAGCGAAATC
TCATCTACACAGCCATTACACGTGCCAAAAGCAAACTCATCTTACTAGGCGAATTACAAGCCTTCGACTATGCTACCCAA
CACATCGGAACTGCCCGAAAAACCTATCTGATTGAACGCTTCAGTGATCTACTGGAGAATGTTGAAGAAAAGCAACAAGC
TGTCTCTGAAACAGTCACATCAAGTGCCTCTGAACAATCCTACATCCTAACCGAAGAAAACTGGGACCGCATCCCAGCCA
TGATTGGGATTACAGACACAGACCTCAAAGAGATTTTTGGAAAATAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix containing domain (HHH_RecD2)

(148-237)

ATP-dependent RecD-like DNA helicase SH3 domain (SH3_13)

(574-644)

UvrD-like helicase C-terminal domain (UvrD_C_2)

(662-709)

AAA domain (AAA_30)

(332-520)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  recD/recD2/recDB Bacillus subtilis subsp. subtilis str. 168

40.885

97.462

0.398