Detailed information NTG0555749

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: LT978_RS19350
• Genome accession: NZ_CP090838
• Coordinates: 3873298..3874380 (-)
• Length: 360 a.a.
• NCBI ID: WP_003156401.1
• Uniprot ID: A0AAI8HS26
• Organism: Bacillus amyloliquefaciens strain TL106
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3868298..3879380

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LT978_RS19325 (LT978_19320)	cysE	3868396..3869049 (-)	654	WP_003156410.1	serine O-acetyltransferase	-
LT978_RS19330 (LT978_19325)	gltX	3869361..3870812 (-)	1452	WP_015388783.1	glutamate--tRNA ligase	-
LT978_RS19335 (LT978_19330)	ispF	3870904..3871380 (-)	477	WP_003156407.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
LT978_RS19340 (LT978_19335)	ispD	3871373..3872071 (-)	699	WP_003156405.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
LT978_RS19345 (LT978_19340)	-	3872084..3873184 (-)	1101	WP_003156403.1	PIN/TRAM domain-containing protein	-
LT978_RS19350 (LT978_19345)	disA	3873298..3874380 (-)	1083	WP_003156401.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
LT978_RS19355 (LT978_19350)	radA/sms	3874384..3875763 (-)	1380	WP_014304212.1	DNA repair protein RadA	Machinery gene
LT978_RS19360 (LT978_19355)	clpC	3875857..3878289 (-)	2433	WP_007410388.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
LT978_RS19365 (LT978_19360)	-	3878286..3879377 (-)	1092	WP_003156398.1	protein arginine kinase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40671.21 Da
• Isoelectric Point: 5.5321

>NTDB_id=555749 LT978_RS19350 WP_003156401.1 3873298..3874380(-) (disA) [Bacillus amyloliquefaciens strain TL106]
MEKEKKGAKQELDLSAILQFVAPGTPLRAGIENVLRANTGGLIVVGYNDKVKQVVDGGFHINTSFAPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPEATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQDSMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTITALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIRLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSILFKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGFLPS
ITEATVEELDDVEGIGEVRAQKIKKGLKRLQEKHYIDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=555749 LT978_RS19350 WP_003156401.1 3873298..3874380(-) (disA) [Bacillus amyloliquefaciens strain TL106]
ATGGAAAAAGAGAAAAAAGGGGCGAAACAAGAGCTTGACCTGTCTGCAATTCTGCAGTTCGTTGCACCGGGCACCCCGCT
CAGAGCCGGGATAGAGAATGTACTTCGGGCAAATACAGGCGGCCTGATTGTTGTCGGATACAATGATAAGGTAAAGCAAG
TCGTGGATGGCGGTTTTCATATTAATACATCATTTGCGCCCGCTCACTTATACGAGCTGGCCAAAATGGACGGTGCCATT
ATTTTAAGTGATTCCGGCCAGAAAATTCTTTATGCGAATACGCAGCTTATGCCGGAGGCGACCATTTCTTCTTCAGAAAC
GGGAATGAGGCACCGTACGGCGGAACGGGTGGCGAAGCAGACCGGCTGTCTCGTCATCGCCATTTCTGAGCGCAGAAATG
TCATTACGTTATATCAGGACAGCATGAAGTACACACTAAAGGACATAGGTTTTATTTTAACAAAGGCAAATCAGGCCATT
CAAACGCTCGAGAAGTATAAAACCATTTTAGACAAAACAATTACGGCTCTAAACGCGTTAGAGTTTGAGGAGCTTGTGAC
ATTCAGTGACGTGCTGTCTGTCATGCATCGGTATGAAATGGTGCTCCGAATAAAAAATGAAATCAATATGTATATTAAAG
AACTCGGAACGGAAGGCCACTTAATCCGTCTGCAGGTGATTGAACTGATTACGGACATGGAAGAAGAGGCGGCACTTTTC
ATCAAAGACTATGTCAAAGAAAAAATCAAAGATCCGTTCGTGCTGTTAAAAGAGCTCCAGGATATGTCCAGCTATGATCT
GCTGGATGATTCCATTCTGTTTAAACTGCTTGGATACCCGGCTTCTACGAATCTTGATGATTATGTGCTCCCGAGAGGCT
ACAGGCTGCTGAACAAAATTCCGCGTCTGCCGATGCCGATTGTTGAAAATGTGGTTGAGGCGTTCGGATTTTTGCCAAGC
ATAACGGAAGCCACTGTAGAAGAGCTTGATGATGTCGAGGGTATCGGCGAAGTGCGCGCCCAAAAAATCAAAAAAGGCTT
AAAACGCCTTCAGGAAAAACACTATATAGATAGACAGCTTTAA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: A0AAI8HS26

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	94.444	100	0.944