Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   SMUNUM_RS05845 Genome accession   NZ_AP014571
Coordinates   1180975..1182762 (-) Length   595 a.a.
NCBI ID   WP_002270646.1    Uniprot ID   -
Organism   Streptococcus mutans LP13     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1175975..1187762
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNUM_RS05815 (SMNUM_1100) - 1176446..1177249 (-) 804 WP_019805421.1 amidohydrolase family protein -
  SMUNUM_RS05820 (SMNUM_1101) - 1177267..1177617 (-) 351 WP_002265574.1 nuclear transport factor 2 family protein -
  SMUNUM_RS05825 (SMNUM_1102) - 1177708..1178010 (+) 303 WP_002265575.1 helix-turn-helix domain-containing protein -
  SMUNUM_RS05830 (SMNUM_1103) - 1178139..1178726 (-) 588 WP_002264094.1 uracil-DNA glycosylase family protein -
  SMUNUM_RS05835 (SMNUM_1104) pepV 1178799..1180211 (-) 1413 WP_286214840.1 dipeptidase PepV -
  SMUNUM_RS05840 (SMNUM_1105) - 1180226..1180828 (-) 603 WP_002263202.1 nitroreductase family protein -
  SMUNUM_RS05845 (SMNUM_1106) uvrC 1180975..1182762 (-) 1788 WP_002270646.1 excinuclease ABC subunit UvrC Machinery gene
  SMUNUM_RS05850 - 1182880..1183940 (+) 1061 Protein_1120 low temperature requirement protein A -
  SMUNUM_RS05855 (SMNUM_1109) - 1183984..1184679 (-) 696 WP_002269348.1 YjjG family noncanonical pyrimidine nucleotidase -
  SMUNUM_RS05860 - 1184758..1185054 (-) 297 WP_024781842.1 TetR/AcrR family transcriptional regulator -
  SMUNUM_RS05865 (SMNUM_1111) eno 1185118..1186416 (-) 1299 WP_002263196.1 surface-displayed alpha-enolase -
  SMUNUM_RS05870 (SMNUM_1112) - 1186813..1187454 (-) 642 WP_002263195.1 DUF4352 domain-containing protein -
  SMUNUM_RS05875 (SMNUM_1113) - 1187492..1187761 (-) 270 WP_002263194.1 hypothetical protein -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68893.28 Da        Isoelectric Point: 9.3836

>NTDB_id=55550 SMUNUM_RS05845 WP_002270646.1 1180975..1182762(-) (uvrC) [Streptococcus mutans LP13]
MNELIKHKLELLPDSPGCYIHKDKNGTIIYVGKAKNLKNRVRSYFHGSHNTKTELLVSEIEDFEYIVTGSNTEALLLEIN
LIQENKPKYNIRLKDDKSYPFIKITNEPYPRLLITRQVKKDGGLYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCF
YYHLGQCKAHTICQTDQTYWDSLKEDVKNFLNGRDDKIVNELRDKMTKASELMEFERAAEYRDLIEGIGLLRTKQRVMNQ
DMQDRDIFGYYVDKGWMCVQVFFIRQGKLIQRDVNMFPYYNESEEDFLTYVGQFYQDNRHFIPKEIFIPRNIDETLVKAV
VNTKIIKPQRGEKKQLVNLATKNARVSLQQKFDLLEKDIRKTHGAIENIGDLLNIPKPVRIEAFDNSNIQGTSPVAAMVV
FVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVMRDGLTPPDLIIIDGGQGQVNVARDVIENKLGLDIPIAGLQ
KNDKHQTHELLFGDPLEVIPLPRNSEEFFLLQRIQDEVHRFAITFHRQLRGKNTFSSKLDGIAGLGPKRKQLLMKHFKNL
PNIQKASLDDIINCGIPKNVAENIQESLREEREKG

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=55550 SMUNUM_RS05845 WP_002270646.1 1180975..1182762(-) (uvrC) [Streptococcus mutans LP13]
ATGAACGAACTGATTAAACATAAGCTGGAATTGCTGCCAGATAGTCCTGGCTGTTATATTCACAAGGATAAAAACGGCAC
CATTATCTATGTCGGTAAGGCCAAGAACTTAAAAAACCGTGTGCGTAGCTATTTTCACGGCAGCCATAATACCAAGACAG
AATTGTTAGTTTCGGAAATTGAGGATTTTGAATACATTGTTACTGGGTCAAATACAGAAGCTTTACTTCTTGAGATTAAT
CTCATTCAGGAAAATAAGCCCAAGTACAATATCAGACTCAAAGATGATAAGTCTTATCCTTTTATTAAAATTACCAATGA
ACCTTATCCGCGTTTATTGATTACCCGTCAGGTGAAAAAGGATGGCGGTCTTTATTTTGGTCCCTACCCTGATTCGGGAG
CTGCTACTGAAATTAAGCGACTTTTAGATCGTCTCTTTCCCTTTAAAAAATGCACCAACCCAGCCAACAAGGTCTGTTTT
TATTATCATCTCGGGCAATGCAAGGCGCATACCATTTGTCAGACCGACCAAACCTATTGGGATAGTCTTAAAGAAGATGT
GAAAAACTTTCTCAATGGCAGGGACGATAAGATTGTCAATGAACTGCGCGATAAAATGACCAAAGCTTCTGAGCTCATGG
AATTTGAACGTGCAGCTGAATACCGAGATCTTATTGAGGGCATTGGTCTGTTGCGAACCAAGCAGCGCGTCATGAATCAG
GATATGCAGGATCGTGATATTTTTGGTTATTATGTTGATAAAGGCTGGATGTGTGTGCAGGTTTTCTTTATTCGTCAGGG
AAAGCTTATTCAGCGCGATGTCAATATGTTTCCTTATTACAATGAGTCTGAGGAAGATTTTCTGACCTATGTAGGACAGT
TCTATCAGGATAACCGTCACTTTATTCCAAAGGAGATTTTTATTCCTAGAAATATTGATGAAACTTTGGTTAAAGCGGTG
GTCAATACTAAGATTATCAAACCGCAGCGCGGCGAGAAGAAGCAGTTAGTCAATCTGGCAACGAAAAATGCTCGTGTTAG
CCTGCAGCAGAAATTTGATCTCTTGGAAAAAGATATTCGAAAAACGCATGGTGCGATTGAAAATATTGGAGATTTACTTA
ATATTCCTAAGCCAGTGCGCATTGAAGCCTTTGATAATTCCAACATTCAAGGAACCAGTCCTGTTGCAGCTATGGTTGTT
TTTGTGGACGGCAAGCCAAGTAAGAAGGATTATCGTAAATTTAAAATCAAAACCGTTATCGGACCTGATGACTATGCCAG
CATGCGTGAGGTTATTTATCGCAGATATAGCCGTGTCATGCGAGATGGACTGACACCACCAGACCTGATTATTATTGATG
GGGGACAAGGTCAGGTTAATGTAGCGCGTGACGTTATCGAAAATAAATTGGGACTCGATATTCCTATCGCTGGTTTGCAA
AAAAATGATAAGCACCAAACCCATGAGCTGCTCTTTGGTGATCCGCTGGAAGTGATTCCTCTGCCTAGAAATTCAGAAGA
GTTCTTTCTCTTGCAGCGCATTCAAGACGAAGTGCATCGCTTTGCCATTACATTTCATAGGCAGCTGCGCGGTAAAAACA
CCTTCTCATCAAAGCTGGACGGTATTGCAGGGCTCGGCCCTAAGCGCAAGCAATTGCTGATGAAACACTTTAAGAATCTT
CCTAATATTCAAAAGGCCAGCCTAGATGATATTATCAACTGCGGCATTCCAAAAAATGTCGCAGAGAACATTCAAGAGAG
CTTGCGAGAGGAAAGAGAAAAAGGTTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(17-90)

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.897

99.664

0.766
  uvrC Streptococcus pneumoniae R6

76.56

99.664

0.763
  uvrC Streptococcus pneumoniae D39

76.56

99.664

0.763

Multiple sequence alignment