Detailed information NTG0055540

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: SMUNUM_RS04750
• Genome accession: NZ_AP014571
• Coordinates: 967905..968576 (+)
• Length: 223 a.a.
• NCBI ID: WP_002263237.1
• Uniprot ID: Q8DUD1
• Organism: Streptococcus mutans LP13
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 962905..973576

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNUM_RS04740 (SMNUM_0891)	-	965106..965858 (+)	753	WP_002272894.1	ABC transporter ATP-binding protein	-
SMUNUM_RS04745 (SMNUM_0892)	-	965860..967863 (+)	2004	WP_002263238.1	ABC transporter permease	-
SMUNUM_RS04750 (SMNUM_0893)	braR	967905..968576 (+)	672	WP_002263237.1	response regulator transcription factor	Regulator
SMUNUM_RS04755 (SMNUM_0894)	-	968573..969526 (+)	954	WP_002263236.1	sensor histidine kinase	-
SMUNUM_RS04760 (SMNUM_0895)	citC	969677..970726 (-)	1050	WP_002263235.1	[citrate (pro-3S)-lyase] ligase	-
SMUNUM_RS04765 (SMNUM_0896)	citG	970902..971792 (-)	891	WP_002263234.1	triphosphoribosyl-dephospho-CoA synthase CitG	-
SMUNUM_RS04770 (SMNUM_0897)	-	971798..972487 (-)	690	WP_002263233.1	GntR family transcriptional regulator	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25802.90 Da
• Isoelectric Point: 5.1691

>NTDB_id=55540 SMUNUM_RS04750 WP_002263237.1 967905..968576(+) (braR) [Streptococcus mutans LP13]
MLKQEKIYLVEDDTTIVNLLKNHLGQHYQVKSVDNFRAILQEVKEFKPDLILMDITLPYFNGFYWTTEIRKSMTMPIIFI
SSADEEMNAVMAMNMGGDDFLSKPFSLPILDAKIAAFLRRANEFTKQGHQIEEFELTLDGVFSNLERQETIQLTPTETKI
LSLLIDYKGEVVTKEALLNRLWEGEEFIDQNTLSVNMTRLRKKVLSVSFDKIHTVRGVGYLIK

Nucleotide

• Length: 672 bp

>NTDB_id=55540 SMUNUM_RS04750 WP_002263237.1 967905..968576(+) (braR) [Streptococcus mutans LP13]
ATGCTAAAGCAAGAAAAAATTTACTTGGTTGAAGATGATACAACCATTGTCAATCTTTTAAAGAATCATTTGGGACAACA
CTATCAAGTTAAAAGCGTTGATAACTTTAGGGCTATCTTGCAAGAAGTTAAAGAATTTAAACCCGATTTAATTCTGATGG
ATATTACTTTGCCCTATTTCAATGGCTTTTATTGGACTACTGAAATCAGAAAGAGCATGACCATGCCCATTATCTTTATT
TCCAGTGCTGATGAAGAAATGAATGCAGTAATGGCTATGAATATGGGAGGTGATGATTTTTTGAGCAAGCCTTTCTCGCT
GCCTATTTTGGATGCCAAAATCGCTGCTTTCTTGCGCCGTGCTAACGAGTTCACTAAGCAAGGCCATCAAATTGAAGAGT
TTGAATTAACGTTAGATGGTGTATTCTCAAATTTAGAAAGACAAGAGACTATCCAATTGACTCCAACAGAAACGAAAATT
CTTTCCTTACTTATTGATTATAAAGGAGAGGTTGTCACTAAGGAAGCTCTTCTCAACCGACTATGGGAGGGAGAGGAATT
TATTGATCAAAACACGCTTAGTGTTAATATGACACGTCTTCGTAAAAAGGTTCTATCAGTAAGTTTTGATAAGATTCATA
CAGTAAGAGGAGTAGGGTATTTAATTAAATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (7-114)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (149-221)

3D structure

• AlphaFold DB: Q8DUD1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	43.498	100	0.435