Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   J7S31_RS05665 Genome accession   NZ_CP072523
Coordinates   1132939..1133976 (-) Length   345 a.a.
NCBI ID   WP_010922499.1    Uniprot ID   A0A4U9I5V9
Organism   Streptococcus pyogenes strain SHZ-1     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1127939..1138976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7S31_RS05645 (J7S31_05630) - 1128670..1129296 (+) 627 WP_002989076.1 A24 family peptidase -
  J7S31_RS05650 (J7S31_05635) rlmN 1129378..1130476 (-) 1099 Protein_1071 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  J7S31_RS05655 (J7S31_05640) - 1130480..1131100 (-) 621 WP_002992791.1 YutD family protein -
  J7S31_RS05660 (J7S31_05645) - 1131548..1132525 (-) 978 WP_011054718.1 LacI family DNA-binding transcriptional regulator -
  J7S31_RS05665 (J7S31_05650) sepM 1132939..1133976 (-) 1038 WP_010922499.1 SepM family pheromone-processing serine protease Regulator
  J7S31_RS05670 (J7S31_05655) coaD 1133963..1134454 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  J7S31_RS05675 (J7S31_05660) rsmD 1134444..1134983 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  J7S31_RS05680 (J7S31_05665) asnA 1135106..1136098 (-) 993 WP_002983817.1 aspartate--ammonia ligase -
  J7S31_RS05685 (J7S31_05670) arcC 1136411..1137361 (-) 951 WP_003051912.1 carbamate kinase -
  J7S31_RS05690 (J7S31_05675) - 1137381..1138712 (-) 1332 WP_011054719.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37541.24 Da        Isoelectric Point: 9.6692

>NTDB_id=553870 J7S31_RS05665 WP_010922499.1 1132939..1133976(-) (sepM) [Streptococcus pyogenes strain SHZ-1]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=553870 J7S31_RS05665 WP_010922499.1 1132939..1133976(-) (sepM) [Streptococcus pyogenes strain SHZ-1]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9I5V9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

69.275

100

0.693