Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   DESDI_RS12815 Genome accession   NC_019903
Coordinates   2693040..2693978 (-) Length   312 a.a.
NCBI ID   WP_015263043.1    Uniprot ID   L0FA43
Organism   Desulfitobacterium dichloroeliminans LMG P-21439     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2677410..2736573 2693040..2693978 within 0


Gene organization within MGE regions


Location: 2677410..2736573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DESDI_RS12710 (Desdi_2635) - 2677705..2678112 (-) 408 WP_015263022.1 NADH-quinone oxidoreductase subunit I -
  DESDI_RS12715 (Desdi_2636) nuoH 2678117..2679175 (-) 1059 WP_015263023.1 NADH-quinone oxidoreductase subunit NuoH -
  DESDI_RS12720 (Desdi_2637) - 2679200..2680312 (-) 1113 WP_015263024.1 NADH-quinone oxidoreductase subunit D -
  DESDI_RS12725 (Desdi_2638) - 2680325..2680816 (-) 492 WP_015263025.1 NADH-quinone oxidoreductase subunit C -
  DESDI_RS12730 (Desdi_2639) - 2680806..2681327 (-) 522 WP_015263026.1 NADH-quinone oxidoreductase subunit B -
  DESDI_RS12735 (Desdi_2640) - 2681318..2681674 (-) 357 WP_015263027.1 NADH-quinone oxidoreductase subunit A -
  DESDI_RS12740 (Desdi_2641) - 2681800..2682579 (-) 780 WP_015263028.1 ribonuclease HII -
  DESDI_RS12745 (Desdi_2642) ylqF 2682524..2683435 (-) 912 WP_015263029.1 ribosome biogenesis GTPase YlqF -
  DESDI_RS12750 (Desdi_2643) lepB 2683465..2683977 (-) 513 WP_041219476.1 signal peptidase I -
  DESDI_RS12755 (Desdi_2644) rplS 2684181..2684522 (-) 342 WP_015263031.1 50S ribosomal protein L19 -
  DESDI_RS12760 (Desdi_2645) - 2684699..2685256 (-) 558 WP_015263032.1 RNA methyltransferase -
  DESDI_RS12765 (Desdi_2646) trmD 2685268..2686086 (-) 819 WP_015263033.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  DESDI_RS12770 (Desdi_2647) rimM 2686088..2686594 (-) 507 WP_015263034.1 ribosome maturation factor RimM -
  DESDI_RS12775 (Desdi_2648) - 2686654..2686884 (-) 231 WP_015263035.1 KH domain-containing protein -
  DESDI_RS12780 (Desdi_2649) rpsP 2686907..2687173 (-) 267 WP_015263036.1 30S ribosomal protein S16 -
  DESDI_RS12785 (Desdi_2650) ffh 2687232..2688593 (-) 1362 WP_015263037.1 signal recognition particle protein -
  DESDI_RS12790 (Desdi_2651) ylxM 2688626..2688994 (-) 369 WP_015263038.1 YlxM family DNA-binding protein -
  DESDI_RS12795 (Desdi_2652) - 2689212..2690507 (-) 1296 WP_015263039.1 amidohydrolase -
  DESDI_RS12800 (Desdi_2653) - 2690567..2691199 (-) 633 WP_015263040.1 class II aldolase/adducin family protein -
  DESDI_RS12805 (Desdi_2654) mtnA 2691199..2692236 (-) 1038 WP_015263041.1 S-methyl-5-thioribose-1-phosphate isomerase -
  DESDI_RS12810 (Desdi_2655) mtnP 2692252..2693043 (-) 792 WP_041219477.1 S-methyl-5'-thioadenosine phosphorylase -
  DESDI_RS12815 (Desdi_2656) pilA 2693040..2693978 (-) 939 WP_015263043.1 signal recognition particle-docking protein FtsY Machinery gene
  DESDI_RS12820 (Desdi_2657) - 2694242..2695642 (-) 1401 WP_041219479.1 nucleoside recognition domain-containing protein -
  DESDI_RS12825 - 2695639..2696388 (-) 750 WP_041219481.1 FeoB small GTPase domain-containing protein -
  DESDI_RS12830 (Desdi_2658) - 2696433..2696681 (-) 249 WP_015263045.1 FeoA family protein -
  DESDI_RS12835 (Desdi_2659) - 2696872..2697309 (-) 438 WP_015263046.1 iron dependent repressor, metal binding and dimerization domain protein -
  DESDI_RS12840 (Desdi_2660) - 2697397..2699190 (-) 1794 WP_015263047.1 hypothetical protein -
  DESDI_RS12845 (Desdi_2661) istB 2700086..2700829 (-) 744 WP_015262273.1 IS21-like element helper ATPase IstB -
  DESDI_RS12850 (Desdi_2662) istA 2700829..2702367 (-) 1539 WP_015262274.1 IS21 family transposase -
  DESDI_RS17340 (Desdi_2663) - 2702507..2704045 (+) 1539 WP_156801135.1 HNH endonuclease -
  DESDI_RS12860 (Desdi_2664) - 2704261..2704629 (-) 369 WP_041219960.1 type II toxin-antitoxin system PemK/MazF family toxin -
  DESDI_RS12865 (Desdi_2665) - 2704639..2704833 (-) 195 WP_015263050.1 hypothetical protein -
  DESDI_RS18295 - 2704993..2705157 (-) 165 WP_242825400.1 hypothetical protein -
  DESDI_RS12870 (Desdi_2666) - 2705133..2705489 (-) 357 WP_242825401.1 ATP-binding protein -
  DESDI_RS12875 (Desdi_2667) - 2705879..2706157 (-) 279 WP_015263051.1 hypothetical protein -
  DESDI_RS18435 (Desdi_2668) - 2706154..2706438 (-) 285 WP_015263052.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
  DESDI_RS12885 (Desdi_2669) - 2706778..2706963 (+) 186 WP_015263053.1 hypothetical protein -
  DESDI_RS12890 (Desdi_2670) - 2707136..2707483 (-) 348 WP_015262315.1 hypothetical protein -
  DESDI_RS12895 (Desdi_2671) - 2707628..2708311 (-) 684 WP_015262316.1 Crp/Fnr family transcriptional regulator -
  DESDI_RS12900 (Desdi_2672) - 2708546..2709808 (-) 1263 WP_000608644.1 IS1380-like element ISEcp1 family transposase -
  DESDI_RS17915 - 2710177..2710341 (+) 165 WP_156801136.1 hypothetical protein -
  DESDI_RS12905 (Desdi_2673) smc 2710454..2714050 (-) 3597 WP_015263054.1 chromosome segregation protein SMC -
  DESDI_RS12910 (Desdi_2674) rnc 2714043..2714831 (-) 789 WP_015263055.1 ribonuclease III -
  DESDI_RS12915 (Desdi_2675) fabF 2714853..2716091 (-) 1239 WP_015263056.1 beta-ketoacyl-ACP synthase II -
  DESDI_RS12920 (Desdi_2676) - 2716121..2717065 (-) 945 WP_015263057.1 nitronate monooxygenase -
  DESDI_RS12925 (Desdi_2677) acpP 2717318..2717545 (-) 228 WP_015263058.1 acyl carrier protein -
  DESDI_RS12930 (Desdi_2678) fabG 2717586..2718329 (-) 744 WP_015263059.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  DESDI_RS12935 (Desdi_2679) fabD 2718331..2719275 (-) 945 WP_015263060.1 ACP S-malonyltransferase -
  DESDI_RS12940 (Desdi_2680) fabK 2720053..2721000 (-) 948 WP_015263061.1 enoyl-[acyl-carrier-protein] reductase FabK -
  DESDI_RS12945 (Desdi_2681) - 2721004..2721999 (-) 996 WP_015263062.1 beta-ketoacyl-ACP synthase III -
  DESDI_RS12950 (Desdi_2682) plsX 2722046..2723050 (-) 1005 WP_015263063.1 phosphate acyltransferase PlsX -
  DESDI_RS12955 (Desdi_2683) fapR 2723068..2723637 (-) 570 WP_015263064.1 transcription factor FapR -
  DESDI_RS12960 (Desdi_2684) ligD 2723797..2726244 (-) 2448 WP_015263065.1 DNA ligase D -
  DESDI_RS12965 (Desdi_2685) - 2726249..2727022 (-) 774 WP_015263066.1 Ku protein -
  DESDI_RS12970 (Desdi_2686) - 2727240..2727473 (-) 234 WP_015263067.1 heavy-metal-associated domain-containing protein -
  DESDI_RS12975 (Desdi_2687) - 2727568..2729421 (-) 1854 WP_015263068.1 heavy metal translocating P-type ATPase -
  DESDI_RS12980 (Desdi_2688) - 2729493..2729795 (-) 303 WP_015263069.1 hypothetical protein -
  DESDI_RS12985 (Desdi_2689) - 2730012..2732051 (-) 2040 WP_015263070.1 alkaline phosphatase family protein -
  DESDI_RS12990 (Desdi_2690) - 2732249..2733982 (-) 1734 WP_015263071.1 methyl-accepting chemotaxis protein -
  DESDI_RS12995 (Desdi_2691) - 2734101..2735114 (-) 1014 WP_015263072.1 tripartite tricarboxylate transporter substrate binding protein -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 34145.15 Da        Isoelectric Point: 4.8381

>NTDB_id=55344 DESDI_RS12815 WP_015263043.1 2693040..2693978(-) (pilA) [Desulfitobacterium dichloroeliminans LMG P-21439]
MAGFFSKLKQGLSKTRDQFVGKVEEILTGRRKIDDELYEELEEVLIRSDVGVNTSLELVERLRKEVKKRKLQEAEELREV
LQELMADLLGTEEAMNFAEQGPSIFLVVGVNGVGKTTTIGKLAHYFRTDGKKVILAAGDTFRAAAIDQLEVWGQRAEVEV
IKQKEGADPAAVAYDALQAAKSRGADLVIMDTAGRLHNKVNLMEELRKVKRVIEREVPGAPHEVLLVLDATTGQNALQQA
KLFQEVAGVTGIVLTKLDGTAKGGVVLGIQGEINIPVKWIGVGEGMEDLRPFNPQDFAGALFDRSPEGVEEG

Nucleotide


Download         Length: 939 bp        

>NTDB_id=55344 DESDI_RS12815 WP_015263043.1 2693040..2693978(-) (pilA) [Desulfitobacterium dichloroeliminans LMG P-21439]
TTGGCAGGTTTTTTTTCGAAATTGAAACAAGGATTATCAAAAACCCGTGATCAATTCGTGGGTAAAGTTGAAGAGATTTT
AACGGGAAGACGCAAAATCGATGATGAACTTTATGAAGAGCTTGAGGAAGTTTTGATTCGTTCAGATGTGGGAGTGAATA
CTTCCTTAGAGCTGGTTGAGAGGCTACGTAAAGAAGTAAAGAAAAGAAAGCTTCAAGAGGCGGAAGAGCTCAGGGAAGTT
CTGCAAGAACTTATGGCTGATTTACTGGGAACAGAGGAGGCTATGAATTTTGCCGAGCAGGGACCAAGTATCTTCCTAGT
AGTTGGTGTAAATGGCGTGGGGAAAACGACGACCATTGGCAAGTTAGCCCACTATTTCCGCACGGATGGGAAGAAGGTCA
TTTTAGCTGCCGGAGATACTTTTCGGGCGGCGGCTATTGATCAGCTTGAGGTCTGGGGACAGCGAGCTGAAGTGGAGGTT
ATTAAGCAGAAAGAGGGCGCAGACCCTGCTGCAGTTGCCTATGATGCACTTCAAGCTGCGAAATCCCGGGGAGCGGATCT
GGTCATTATGGATACGGCCGGACGGCTCCACAATAAAGTGAATTTAATGGAAGAATTACGCAAGGTCAAACGGGTGATTG
AACGTGAGGTTCCCGGAGCACCCCATGAAGTGTTGTTGGTTCTAGACGCTACAACCGGGCAGAACGCACTTCAACAAGCT
AAGCTTTTTCAGGAAGTAGCGGGTGTAACTGGAATTGTGCTCACGAAGTTGGATGGAACGGCAAAAGGCGGCGTCGTCTT
AGGTATTCAAGGAGAGATTAATATTCCGGTGAAATGGATTGGTGTTGGGGAAGGGATGGAAGATTTGCGTCCCTTTAATC
CTCAGGACTTTGCGGGGGCTCTTTTTGACCGTTCGCCAGAAGGGGTTGAAGAGGGCTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(102-302)

SRP54-type protein, helical bundle domain (SRP54_N)

(22-83)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB L0FA43

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

49.505

97.115

0.481

Multiple sequence alignment