Detailed information NTG0553086

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: J7T69_RS01500
• Genome accession: NZ_CP072438
• Coordinates: 272335..273234 (+)
• Length: 299 a.a.
• NCBI ID: WP_014607953.1
• Uniprot ID: A0AAN1ZWJ0
• Organism: Streptococcus thermophilus strain S24733
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 267335..278234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7T69_RS01480 (J7T69_01485)	trkA	268471..269820 (-)	1350	WP_014607951.1	Trk system potassium transporter TrkA	-
J7T69_RS01485 (J7T69_01490)	-	270109..270618 (+)	510	WP_014607952.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
J7T69_RS01490 (J7T69_01495)	-	270930..271487 (+)	558	WP_002949523.1	ECF transporter S component	-
J7T69_RS01495 (J7T69_01500)	-	271490..272140 (+)	651	WP_011225447.1	phosphatase PAP2 family protein	-
J7T69_RS01500 (J7T69_01505)	comR	272335..273234 (+)	900	WP_014607953.1	helix-turn-helix domain-containing protein	Regulator
J7T69_RS01505	-	273472..273903 (+)	432	Protein_243	cysteine peptidase family C39 domain-containing protein	-
J7T69_RS01510	-	273933..274649 (+)	717	Protein_244	ABC transporter transmembrane domain-containing protein	-
J7T69_RS01515	comA	274671..274880 (+)	210	WP_002946147.1	hypothetical protein	Regulator
J7T69_RS01520 (J7T69_01530)	-	274935..275503 (+)	569	Protein_246	ATP-binding cassette domain-containing protein	-
J7T69_RS01525 (J7T69_01535)	-	275611..275928 (+)	318	WP_011225454.1	DUF805 domain-containing protein	-
J7T69_RS01530	-	275891..276175 (-)	285	WP_014727318.1	hypothetical protein	-
J7T69_RS01535	-	276415..277311 (-)	897	WP_224102957.1	urease cluster protein	-
J7T69_RS01540 (J7T69_01545)	-	277716..278231 (+)	516	WP_002949547.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35289.70 Da
• Isoelectric Point: 5.0061

>NTDB_id=553086 J7T69_RS01500 WP_014607953.1 272335..273234(+) (comR) [Streptococcus thermophilus strain S24733]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLVIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIENS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=553086 J7T69_RS01500 WP_014607953.1 272335..273234(+) (comR) [Streptococcus thermophilus strain S24733]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAGTCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAACTCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	41.806	100	0.418