Detailed information NTG0553030

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: LV497_RS05280
• Genome accession: NZ_CP090007
• Coordinates: 1173922..1176480 (+)
• Length: 852 a.a.
• NCBI ID: WP_073687856.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain SALI-10
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1168922..1181480

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LV497_RS05250 (LV497_05250)	-	1170104..1170298 (+)	195	WP_004181980.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
LV497_RS05255 (LV497_05255)	-	1170325..1170525 (+)	201	WP_004181983.1	hypothetical protein	-
LV497_RS05260 (LV497_05260)	-	1170518..1170673 (+)	156	WP_004181943.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
LV497_RS05265 (LV497_05265)	argS	1171296..1172987 (-)	1692	WP_073687854.1	arginine--tRNA ligase	-
LV497_RS05270 (LV497_05270)	argR	1173142..1173570 (+)	429	WP_171963651.1	arginine repressor	-
LV497_RS05275 (LV497_05275)	-	1173570..1173929 (+)	360	WP_073687855.1	YlbF family regulator	-
LV497_RS05280 (LV497_05280)	hexA	1173922..1176480 (+)	2559	WP_073687856.1	DNA mismatch repair protein MutS	Machinery gene
LV497_RS05285 (LV497_05285)	-	1176514..1176969 (-)	456	WP_073687857.1	DUF3021 domain-containing protein	-
LV497_RS05290 (LV497_05290)	brsR	1176966..1177403 (-)	438	WP_014633775.1	LytTR family DNA-binding domain-containing protein	Regulator
LV497_RS05295 (LV497_05295)	-	1177582..1177887 (+)	306	WP_002886319.1	hypothetical protein	-
LV497_RS05300 (LV497_05300)	hexB	1177937..1179880 (+)	1944	WP_022495805.1	DNA mismatch repair endonuclease MutL	Machinery gene
LV497_RS05305 (LV497_05305)	-	1180011..1180232 (+)	222	WP_022495804.1	hypothetical protein	-
LV497_RS05310 (LV497_05310)	ruvA	1180390..1180980 (+)	591	WP_002886323.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95595.83 Da
• Isoelectric Point: 4.6650

>NTDB_id=553030 LV497_RS05280 WP_073687856.1 1173922..1176480(+) (hexA) [Streptococcus salivarius strain SALI-10]
MAKEKISPGMQQYLDIKENYPDAFLLFRMGDFYELFYEDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKAGSRFGLAYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDTSLTDLESSVAGKLLQYVHRTQMRELSHLQK
AQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQAVIMERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILESFDDEALSRLLQELDALPELESLIRSAIDP
DAPATITEGGIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKTEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVTAETNHYVRPVFN
DEHRIVIDQGRHAVVEKVMGVQEYIPNTITFDSQTNVQLITGPNMSGKSTYMRQLALSVVMAQMGSYVPADSIDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNTLTHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGETVTIQPQEKVSPQ
EKPATEKHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=553030 LV497_RS05280 WP_073687856.1 1173922..1176480(+) (hexA) [Streptococcus salivarius strain SALI-10]
ATGGCTAAGGAAAAAATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTCTT
TCGTATGGGTGATTTTTACGAATTATTTTACGAGGATGCCGTTAAGGCTGCCCAAATTTTGGAAATTAGCCTAACCAGTC
GTAATAAGAATGCCGATAATCCTATTCCTATGGCTGGTGTTCCTTATCATTCAGCTCAAGCTTATATTGATGTCTTGGTT
GAGATGGGCTACAAGGTAGCCATTGCTGAGCAGATGGAGGATCCTAAACAGGCTGTTGGTGTGGTTAAGCGTGAGGTGGT
TCAGGTTATCACGCCAGGGACAGTGGTTGACAGTTCTAAACCTGATAATGCCAACAATTTCTTGGTAGCCATTGACAAGG
CTGGAAGTCGTTTTGGTCTGGCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGACGATTTCAGTTCA
GTTTGTAGTGAAATTCAGAACCTTAAGGCACGTGAAGTAGTGGTTGGTTATGATTTACCTGAAGCTGATGAACAAGTTTT
GGTGAAGCAACTCAACCTTCTACTTTCCAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACACTAGCTTGACAG
ACTTGGAAAGCAGTGTAGCGGGTAAACTTCTCCAGTATGTGCACCGTACTCAGATGCGTGAGCTCAGCCATTTACAAAAG
GCTCAGCACTATGAGATTAAGGATTACTTGCAGATGTCTTATGCGACCAAGTCAAGTTTGGATTTGTTGGAAAATGCGAG
AACGGGCAAGAAACACGGTTCTCTTTTCTGGCTCTTGGATGAAACCAAGACAGCTATGGGGATGCGTCTCTTACGCACTT
GGATTGACCGTCCTTTAGTGAATCAGGCTGTAATCATGGAGCGCCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTC
GAGCGTAGTGACTTGACTGAGAGTCTTAAAGGGGTTTACGATATTGAGCGCTTGGCTAGTCGTGTTTCCTTCGGAAAGGC
TAATCCTAAAGATTTGATTCAACTAGGTCATACCTTAGCTCAGGTTCCGGTCATTAAGGCAATTTTGGAGTCTTTTGATG
ATGAGGCCTTGTCACGTCTTTTACAAGAGTTAGATGCTCTGCCAGAATTAGAGAGTCTGATTCGGTCGGCTATCGATCCC
GATGCTCCTGCAACCATTACAGAAGGTGGCATTATTCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGAT
GAGTGAGGGGACGTCATGGATCGCAGACATCGAAGCCAAGGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACCAACTCTAATCTTAGCTTGGTCCCTGACCATTTCTTCCGCAAGGCA
ACCCTGAAAAATTCAGAGCGCTTTGGAACTGCTGAGTTGGCTAAGACTGAAGGTGAGATGCTTGAGGCACGTGAAAAGTC
ATCAACGCTAGAGTATGATATTTTCATGCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTA
AGGCTATTGCGACAGTCGATGTACTTCAGAGTTTAGCAGTTACAGCAGAGACTAATCATTATGTTCGTCCTGTGTTCAAT
GATGAGCATCGTATCGTTATTGATCAAGGCCGTCATGCGGTGGTTGAGAAGGTTATGGGCGTTCAGGAATACATTCCAAA
CACGATTACCTTTGACAGTCAGACCAATGTTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCTACCTATATGCGTC
AGTTGGCCTTGTCAGTCGTTATGGCTCAGATGGGGTCTTACGTGCCAGCAGATAGTATTGATTTGCCAGTTTTTGACGCC
ATCTATACACGTATTGGTGCTGCAGATGACTTGATTTCAGGTCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAACCA
GGCCATTAAGCGGGCGACACCTAATTCCTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCCACCTATGATGGTATGG
CTTTGGCCCAGTCTATTATTGAGTTTATTCATGACAAGGTGGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTG
ACAGCCCTGTCAAATACTTTGACACACCTTGTCAACGTTCATGTGGCGACACTTGAAAAGGACGGAGAGGTGACTTTCCT
TCACAAGATTGTCGATGGCCCAGCCGATAAATCTTATGGTATTCATGTGGCTAAGATTGCAGGTTTACCAGCAGATTTAC
TGGAACGTGCTGACACCATCTTGACACAATTAGAGGGCGAGACAGTTACCATCCAACCTCAGGAAAAGGTATCGCCTCAA
GAGAAGCCAGCCACTGAAAAACATGTCAACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCGGTTCTTCAAGA
GTTACGTGATTTGGATATTTACAATATGACACCGATGCAGGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.061	100	0.741
mutS	Pseudomonas stutzeri strain ATCC 17587	36.185	100	0.367