Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   LV497_RS03010 Genome accession   NZ_CP090007
Coordinates   740013..742118 (-) Length   701 a.a.
NCBI ID   WP_245085244.1    Uniprot ID   -
Organism   Streptococcus salivarius strain SALI-10     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 735013..747118
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LV497_RS02975 (LV497_02975) pptB 735809..736846 (-) 1038 WP_022496186.1 ABC transporter permease Regulator
  LV497_RS02980 (LV497_02980) pptA 736843..737574 (-) 732 WP_022496187.1 ABC transporter ATP-binding protein Regulator
  LV497_RS02985 (LV497_02985) - 737639..738058 (+) 420 WP_002891660.1 HIT family protein -
  LV497_RS02990 (LV497_02990) - 738055..738354 (+) 300 WP_022496188.1 hypothetical protein -
  LV497_RS02995 (LV497_02995) - 738371..738721 (-) 351 WP_183139907.1 ribonuclease -
  LV497_RS03000 (LV497_03000) - 738759..739103 (-) 345 WP_155123768.1 hypothetical protein -
  LV497_RS03005 (LV497_03005) - 739122..739619 (-) 498 WP_245085241.1 hypothetical protein -
  LV497_RS03010 (LV497_03010) clpE 740013..742118 (-) 2106 WP_245085244.1 AAA family ATPase Regulator
  LV497_RS03015 (LV497_03015) - 742834..743088 (-) 255 WP_014634942.1 Txe/YoeB family addiction module toxin -
  LV497_RS03020 (LV497_03020) - 743092..743346 (-) 255 WP_013991075.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  LV497_RS03025 (LV497_03025) - 743488..744579 (-) 1092 WP_245085247.1 nucleotidyltransferase -
  LV497_RS03030 (LV497_03030) - 744586..745326 (-) 741 WP_179969005.1 class I SAM-dependent methyltransferase -
  LV497_RS03035 (LV497_03035) rsfS 745531..745884 (-) 354 WP_084869239.1 ribosome silencing factor -
  LV497_RS03040 (LV497_03040) yqeK 745907..746497 (-) 591 WP_084869237.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77324.26 Da        Isoelectric Point: 4.7435

>NTDB_id=552996 LV497_RS03010 WP_245085244.1 740013..742118(-) (clpE) [Streptococcus salivarius strain SALI-10]
MNNNFNNMDDLFNQLMGNMGGYRSENRRYMINGREVTPEEFAIYRQTGQLPGNEGEAVNPTQQQGKGPKQDGILAKLGRN
LTEEAREGKLDPVIGRNKEIQEACEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTILK
NAALARRFNEVKVNAPSAEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDVNAVEHEIEAEKAKQEAAAAKEDYEAALNAKVRIEELEKKIANHTEDLKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGHRLQTKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLVEVNKTLSKKDIDLAVSEA
AKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=552996 LV497_RS03010 WP_245085244.1 740013..742118(-) (clpE) [Streptococcus salivarius strain SALI-10]
ATGAACAACAACTTTAACAATATGGACGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTACCGTTCAGAAAACCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCTATCTACCGTCAAACAGGTCAATTGCCTGGTAATG
AAGGTGAAGCAGTGAACCCAACTCAACAACAAGGTAAAGGACCTAAACAAGACGGTATCCTTGCTAAACTTGGTCGTAAC
TTGACTGAAGAAGCTCGCGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAGCTTGCGAAATCTT
GGCTCGTCGTACCAAGAATAACCCAGTCCTTGTCGGGGATGCTGGCGTTGGTAAAACAGCCGTAGTTGAAGGTTTGGCTC
AAGCCATCGTCAATGGTGATGTCCCAGCTGCTATCAAGAACAAGGAAATCATCTCAATTGATATTTCTGGACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAACGAAGTTAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATCCACCAAATTCTTGGTGCCGGAAGCACTGGTGATGGTCAAGGATCTAAAGGTCTTGCTGATATCT
TGAAACCAGCTCTTTCACGTGGTGAATTGACAGTGATTGGTGCAACAACTCAGGATGAATACCGTAACACTATCTTGAAG
AACGCTGCCCTAGCTCGTCGTTTTAACGAAGTTAAGGTCAATGCTCCTTCTGCTGAAGATACCTTCAAGATTCTTCAAGG
TATCCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTTTTGAAAGCAGCGGTAGATTTCTCTGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATCGACCTTGTCGATGTAACAGCTGCTCACTTGGCTGCTCAACAC
CCAGTGACTGATGTGAATGCTGTTGAACATGAAATTGAAGCTGAAAAAGCTAAACAAGAAGCTGCAGCTGCCAAAGAAGA
CTACGAAGCAGCTCTAAACGCTAAGGTTCGTATTGAAGAACTTGAAAAGAAAATTGCTAACCATACAGAAGACCTTAAAG
TCACTGCAACTGTTAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATCCCAGTATCGCAAATGGGAGCAACTGAT
ATTGAACGTCTGAAAGACATGGGTCACCGTTTGCAAACCAAGGTTATCGGTCAAGATAAAGCTGTTGAAGCAGTGGCACG
TGCCATCCGTCGTAACCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCTCTTGATATGTTCGGTACTAAAGATGCCATTATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAATAC
TTTGACAGAACGTGTTCGCCGTAACCCATACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTCATCA
CCCTTCTCCTCCAAGTTTTGGACGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTGATT
ATCGCAACTTCAAACGCAGGCTTTGGTTATGAAGCTAACTTGACAGAAGATGCTGATAAACCAGAACTTATGGATCGTTT
GAAACCTTACTTCCGTCCAGAATTCCTTAACCGTTTCAATGCTGTCATCGAATTCTCACACTTGAGCAAAGAAGATCTTT
CTAAGATTGTAGACCTTATGTTGGTTGAAGTTAACAAGACGCTTTCTAAGAAAGACATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGAATACATGACTGAAGAAGGCTACGACGAAGTCATGGGTGTTCGTCCACTCCGTCGTGTGGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTGG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(116-248)

AAA lid domain (AAA_lid_9)

(257-352)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

47.361

100

0.474
  clpC Lactococcus lactis subsp. cremoris KW2

49.923

93.153

0.465
  clpE Streptococcus pneumoniae D39

49.224

91.869

0.452
  clpE Streptococcus pneumoniae R6

49.224

91.869

0.452
  clpE Streptococcus pneumoniae Rx1

49.224

91.869

0.452
  clpE Streptococcus pneumoniae TIGR4

48.989

91.726

0.449
  clpC Bacillus subtilis subsp. subtilis str. 168

46.296

92.439

0.428
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.243

92.867

0.392
  clpC Streptococcus pneumoniae TIGR4

44.013

88.16

0.388
  clpC Streptococcus pneumoniae Rx1

44.013

88.16

0.388
  clpC Streptococcus pneumoniae D39

44.013

88.16

0.388
  clpC Streptococcus thermophilus LMD-9

43.274

88.017

0.381
  clpC Streptococcus thermophilus LMG 18311

42.811

88.302

0.378
  clpC Streptococcus mutans UA159

42.308

89.016

0.377