Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   J7T77_RS03135 Genome accession   NZ_CP072430
Coordinates   581094..583352 (-) Length   752 a.a.
NCBI ID   WP_372589717.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24746     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 576094..588352
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T77_RS03100 - 576489..576725 (+) 237 WP_011226995.1 hypothetical protein -
  J7T77_RS03105 - 576775..577110 (+) 336 Protein_549 DUF3862 domain-containing protein -
  J7T77_RS03110 (J7T77_03025) - 577323..577865 (+) 543 WP_014621342.1 TVP38/TMEM64 family protein -
  J7T77_RS03115 (J7T77_03030) - 577843..579078 (+) 1236 WP_014608114.1 aminoacyltransferase -
  J7T77_RS03120 (J7T77_03035) - 579177..580139 (+) 963 Protein_552 Gfo/Idh/MocA family protein -
  J7T77_RS03125 (J7T77_03040) - 580181..580483 (-) 303 WP_084825858.1 DUF1827 family protein -
  J7T77_RS03130 (J7T77_03045) - 580493..580951 (-) 459 WP_002950198.1 NUDIX hydrolase -
  J7T77_RS03135 (J7T77_03050) clpE 581094..583352 (-) 2259 WP_372589717.1 AAA family ATPase Regulator
  J7T77_RS03140 (J7T77_03055) argF 583593..584573 (+) 981 WP_084828593.1 ornithine carbamoyltransferase -
  J7T77_RS03145 (J7T77_03060) - 584642..584872 (+) 231 WP_011225686.1 DUF1797 family protein -
  J7T77_RS03150 (J7T77_03065) - 585141..585821 (+) 681 WP_014608117.1 amino acid ABC transporter permease -
  J7T77_RS03155 (J7T77_03070) - 585821..586555 (+) 735 WP_002950207.1 amino acid ABC transporter ATP-binding protein -
  J7T77_RS03160 (J7T77_03075) - 586729..587205 (+) 477 WP_084828595.1 ferrous iron transport protein A -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83786.91 Da        Isoelectric Point: 5.1506

>NTDB_id=552691 J7T77_RS03135 WP_372589717.1 581094..583352(-) (clpE) [Streptococcus thermophilus strain S24746]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQHCYKIIKSDPENPLNQFNQAGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGPGRPGGPRQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNTGDGNM
DAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAITAAA
ELSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFIDPKDLDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQQQTI
KDQDMPIITEKHIEAIVEQKTNIPIGDLKEKEQSQLLNLADDLKAHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSSDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEKAH
PDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVINHLGDFFSPEFMNRFDGIIE
FSALSKENLLTIVDLMLDGVNQRLANNGIHLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDTITDFYLKNPNEKDL
KAVMTSKGHITIKSAQKTEKTSQKTEALKEVN

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=552691 J7T77_RS03135 WP_372589717.1 581094..583352(-) (clpE) [Streptococcus thermophilus strain S24746]
ATGCTCTGCCAAAACTGTAACCTTAATGAAGCTAGTATCCATTTGTATACCAACGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAACATTGTTATAAAATCATAAAATCTGATCCAGAGAACCCCCTTAACCAATTCAATCAAGCAGGAGGTTCCA
ACTTCTTCGACGATTTCTTCAGTGACCTAAACAACTTCCGTTCTTCTAACGGAGACCTTCCTAATACACCTCCAACACAA
GAGGGAGGTAACCGTGGAAACGGTGGTCCAGGCCGTCCTGGAGGACCACGTCAACAAGCCCCTCAACAACCTCAAGGCCT
TCTCGAAGAATTTGGAATTAATATCACAGATATTGCTCGTCGTGGAGACATTGATCCTGTCATTGGTCGTGACGAAGAAA
TCATTCGCGTCATCGAAATTCTGAACCGCCGTACCAAGAACAATCCTGTTCTTATCGGTGAACCTGGTGTTGGTAAGACC
GCAGTAGTCGAAGGACTTGCCCAAAAAATCGTTGATGGAGATGTGCCACAAAAACTCCAAAGCAAGCAAGTTATCCGTCT
TGATGTTGTAAGCCTAGTTCAAGGGACTGGTATCCGCGGCCAGTTCGAAGAACGCATGCAAAAGCTCATGGAGGAAATCC
GCCAACGTCAGGATGTTATCCTCTTTATTGATGAAATCCATGAAATTGTAGGAGCTGGTAATACTGGGGACGGCAATATG
GATGCTGGAAACATCTTAAAACCTGCACTTGCCCGTGGAGAGCTTCAACTTGTTGGAGCAACAACACTCAACGAATACCG
TATCATTGAGAAAGATGCGGCACTCGAACGTCGTATGCAACCTGTTAAGGTAGATGAGCCAACAGTTGAGGAAACAATCA
CAATTTTGCGTGGTATCCAGCCTAAATATCAAGACTACCACCATGTCAAATACACTGATGAAGCCATTACTGCAGCTGCA
GAATTATCCAACCGCTACATTCAGGACCGTTTCTTGCCAGACAAGGCCATCGACCTTCTCGATGAATCTGGCTCTAAGAT
GAATTTAACCCTCAACTTTATCGATCCTAAGGACCTCGATAAACGTTTGATTGAAGCTGAGAATCTTAAAGCTCAGGCTA
CTCGCGACGAAGACTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCTAAATACAAGGAAATGCAACAGCAAACCATC
AAAGACCAAGATATGCCTATCATTACTGAAAAACATATCGAAGCCATTGTCGAGCAAAAAACCAATATTCCTATCGGTGA
TTTAAAAGAAAAAGAACAATCTCAACTTCTCAACCTCGCCGATGACCTTAAGGCGCATGTTATTGGCCAAGATGCCGCAG
TTGATAAGATTGCCAAAGCTATCCGCCGTAATCGTGTTGGACTTGGTGCACCAAACCGCCCAATTGGTAGCTTCCTATTT
GTAGGCCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAGTTAGCCATCGAGCTCTTTGGTTCATCTGATAGTATGAT
TCGTTTTGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTCGGTGCTCCTCCAGGCTATGTTGGTTACG
ACGAAGCTGGGCAATTAACCGAAAAGGTCCGCCGTAACCCTTATTCACTCATTCTCCTTGATGAGGTTGAAAAAGCTCAC
CCAGATGTGCTTCACATGTTCCTTCAGGTACTTGACGATGGTCGTCTGACTGATGGTCAAGGGAGAACTGTAAGTTTCAA
AGATACCATCATCATCATGACTTCAAATGCTGGTACTGGTAAAGTGGAAGCAAGTGTAGGTTTTGGAGCTGCTCGTGAGA
ATCGTACCAATTCTGTTATCAACCACCTTGGAGATTTCTTCAGTCCTGAATTCATGAACCGTTTTGACGGTATTATCGAG
TTCTCTGCCCTAAGCAAGGAAAATCTCCTTACTATCGTGGACCTTATGCTTGATGGCGTCAACCAACGCTTGGCAAACAA
CGGTATCCACCTCAGTGTGACTGATAAAGTTAAGGAAAAACTGGTTGACCTTGGTTATGATCCTAAGATGGGTGCTCGAC
CATTGCGTCGTACAATCCAAGACCACATCGAAGATACCATTACAGACTTCTACCTTAAAAATCCAAATGAAAAAGATCTC
AAGGCTGTAATGACTTCAAAGGGACACATCACCATTAAATCTGCTCAAAAAACTGAAAAAACTTCTCAGAAAACTGAAGC
ATTAAAAGAAGTCAACTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(288-386)

ATPase family associated with various cellular activities (AAA) (AAA)

(150-269)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(644-717)

AAA domain (Cdc48 subfamily) (AAA_2)

(473-636)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

84.421

99.867

0.843
  clpE Streptococcus pneumoniae Rx1

82.181

100

0.822
  clpE Streptococcus pneumoniae D39

82.181

100

0.822
  clpE Streptococcus pneumoniae R6

82.181

100

0.822
  clpE Streptococcus pneumoniae TIGR4

82.048

100

0.82
  clpC Lactococcus lactis subsp. cremoris KW2

76.636

99.601

0.763
  clpC Bacillus subtilis subsp. subtilis str. 168

51.772

86.303

0.447
  clpC Streptococcus pneumoniae TIGR4

46.401

86.835

0.403
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.037

87.234

0.402
  clpC Streptococcus pneumoniae D39

46.984

83.777

0.394
  clpC Streptococcus pneumoniae Rx1

46.984

83.777

0.394
  clpC Streptococcus mutans UA159

46.326

83.245

0.386
  clpC Streptococcus thermophilus LMD-9

46.4

83.112

0.386
  clpC Streptococcus thermophilus LMG 18311

46.08

83.112

0.383