Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   J7U22_RS05940 Genome accession   NZ_CP072428
Coordinates   1150288..1152546 (+) Length   752 a.a.
NCBI ID   WP_372588783.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24749     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1145288..1157546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U22_RS05915 (J7U22_05905) - 1146434..1146911 (-) 478 Protein_1150 ferrous iron transport protein A -
  J7U22_RS05920 (J7U22_05910) - 1147085..1147819 (-) 735 WP_002950207.1 amino acid ABC transporter ATP-binding protein -
  J7U22_RS05925 (J7U22_05915) - 1147819..1148499 (-) 681 WP_014608117.1 amino acid ABC transporter permease -
  J7U22_RS05930 (J7U22_05920) - 1148768..1148998 (-) 231 WP_011225686.1 DUF1797 family protein -
  J7U22_RS05935 (J7U22_05925) argF 1149067..1150047 (-) 981 WP_179970722.1 ornithine carbamoyltransferase -
  J7U22_RS05940 (J7U22_05930) clpE 1150288..1152546 (+) 2259 WP_372588783.1 AAA family ATPase Regulator
  J7U22_RS05945 (J7U22_05935) - 1152615..1153871 (-) 1257 WP_011681055.1 ISL3-like element ISSth1 family transposase -
  J7U22_RS05950 (J7U22_05940) - 1154113..1154571 (+) 459 WP_002947302.1 NUDIX hydrolase -
  J7U22_RS05955 (J7U22_05945) - 1154581..1154883 (+) 303 WP_014608115.1 DUF1827 family protein -
  J7U22_RS05960 (J7U22_05950) - 1154924..1155887 (-) 964 Protein_1159 Gfo/Idh/MocA family protein -
  J7U22_RS05965 (J7U22_05955) - 1155986..1157221 (-) 1236 WP_002950192.1 aminoacyltransferase -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83698.89 Da        Isoelectric Point: 5.2734

>NTDB_id=552578 J7U22_RS05940 WP_372588783.1 1150288..1152546(+) (clpE) [Streptococcus thermophilus strain S24749]
MLCQNCNLNEASIHLYTNVNGNQQQVDLCQHCYKIIKSDPENPLNQFNQAGGSNFFDDFFSDLNNFRSSNGDLPNTPPTQ
EGGNRGNGGPGRPGGPRQQAPQQPQGLLEEFGINITDIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVGKT
AVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAGNTGDGNM
DAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILRGIQPKYQDYHHVKYTDEAITAAA
ELSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFIDPKDLDKRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEMQQQTI
KDQDMPIITEKHIEAIVEQKTNIPIGDLKEKEQSQLLNLADDLKAHVIGQDAAVDKIAKAIRRNRVGLGAPNRPIGSFLF
VGPTGVGKTELSKQLAIELFGSSDSMIRFDMSEYMEKHAVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEKAH
PDVLHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAARENRTNSVINHLGDFFSPEFMNRFDGIIE
FSALSKENLLTIVDLMLDGVNQRLANNGIHLSVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLKNPNEKGL
KAVMTSKGHITIKSAKKTEKTSQKTEALKEVN

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=552578 J7U22_RS05940 WP_372588783.1 1150288..1152546(+) (clpE) [Streptococcus thermophilus strain S24749]
ATGCTCTGCCAAAACTGTAACCTTAATGAAGCTAGTATCCATTTGTATACCAACGTAAATGGTAATCAGCAACAAGTTGA
CCTCTGTCAACATTGTTATAAAATCATAAAATCTGATCCAGAGAACCCCCTTAACCAATTCAATCAAGCAGGAGGTTCCA
ACTTCTTCGACGATTTCTTCAGTGACCTAAACAACTTCCGTTCTTCTAACGGAGACCTTCCTAATACACCTCCAACACAA
GAGGGAGGTAACCGTGGAAACGGTGGTCCAGGCCGTCCTGGAGGACCACGTCAACAAGCCCCTCAACAACCTCAAGGCCT
TCTCGAAGAATTTGGAATTAATATCACAGATATTGCTCGTCGTGGAGACATTGATCCTGTCATTGGTCGTGACGAAGAAA
TCATTCGCGTCATCGAAATTCTGAACCGCCGTACCAAGAACAATCCTGTTCTTATCGGTGAACCTGGTGTTGGTAAGACC
GCAGTAGTCGAAGGACTTGCCCAAAAAATCGTTGATGGAGATGTGCCACAAAAACTCCAAAGCAAGCAAGTTATCCGTCT
TGATGTTGTAAGCCTAGTTCAAGGGACTGGTATCCGCGGCCAGTTCGAAGAACGCATGCAAAAGCTCATGGAGGAAATCC
GCCAACGTCAGGATGTTATCCTCTTTATTGATGAAATCCATGAAATTGTAGGAGCTGGTAATACTGGGGACGGCAATATG
GATGCTGGAAACATCTTAAAACCTGCACTTGCCCGTGGAGAGCTTCAACTTGTTGGAGCAACAACACTCAACGAATACCG
TATCATTGAGAAAGATGCGGCACTCGAACGTCGTATGCAACCTGTTAAGGTAGATGAGCCAACAGTTGAGGAAACAATCA
CAATTTTGCGTGGTATCCAGCCTAAATATCAAGACTACCACCATGTCAAATACACTGATGAAGCCATTACTGCAGCTGCA
GAATTATCCAACCGCTACATTCAGGACCGTTTCTTGCCAGACAAGGCCATCGACCTTCTCGATGAATCTGGCTCTAAGAT
GAATTTAACCCTCAACTTTATCGATCCTAAGGACCTCGATAAACGTTTGATTGAAGCTGAGAATCTTAAAGCTCAGGCTA
CTCGCGACGAAGACTTTGAAAAAGCTGCTTATTTCCGTGACCAAATTGCTAAATACAAGGAAATGCAACAGCAAACCATC
AAAGACCAAGATATGCCTATCATTACTGAAAAACATATCGAAGCCATTGTCGAGCAAAAAACCAATATTCCTATCGGTGA
TTTAAAAGAAAAAGAACAATCTCAACTTCTCAACCTCGCCGATGACCTTAAGGCGCATGTTATTGGCCAAGATGCCGCAG
TTGATAAGATTGCCAAAGCTATCCGCCGTAATCGTGTTGGACTTGGTGCACCAAACCGCCCAATTGGTAGCTTCCTATTT
GTAGGCCCTACAGGAGTCGGTAAAACTGAGCTCTCTAAACAGTTAGCCATCGAGCTCTTTGGTTCATCTGATAGTATGAT
TCGTTTTGACATGTCAGAATACATGGAAAAACACGCTGTTGCTAAATTGGTCGGTGCTCCTCCAGGCTATGTTGGTTACG
ACGAAGCTGGGCAATTAACCGAAAAGGTCCGCCGTAACCCTTATTCACTCATTCTCCTTGATGAGGTTGAAAAAGCTCAC
CCAGATGTGCTTCACATGTTCCTTCAGGTACTTGACGATGGTCGTCTGACTGATGGTCAAGGGAGAACTGTAAGTTTCAA
AGATACCATCATCATCATGACTTCAAATGCTGGTACTGGTAAAGTGGAAGCAAGTGTAGGTTTTGGAGCTGCTCGTGAGA
ATCGTACCAATTCTGTTATCAACCACCTTGGAGATTTCTTCAGTCCTGAATTCATGAACCGTTTTGACGGTATTATCGAG
TTCTCTGCCCTAAGCAAGGAAAATCTCCTTACTATCGTGGACCTTATGCTTGATGGCGTCAACCAACGCTTGGCAAACAA
CGGTATCCACCTCAGTGTGACTGATAAAGTTAAGGAAAAACTGGTTGACCTTGGTTATGATCCTAAGATGGGTGCTCGAC
CATTGCGTCGTACAATCCAAGACCACATCGAAGATGCCATTACAGACTTCTACCTTAAAAATCCAAATGAAAAAGGTCTC
AAGGCTGTAATGACTTCAAAGGGACACATCACCATTAAATCTGCTAAAAAAACTGAAAAAACTTCTCAGAAAACTGAAGC
ATTAAAAGAAGTCAACTAA

Domains

Predicted by InterProScan.

AAA lid domain (AAA_lid_9)

(288-386)

ATPase family associated with various cellular activities (AAA) (AAA)

(150-269)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(644-719)

AAA domain (Cdc48 subfamily) (AAA_2)

(473-636)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

84.554

99.867

0.844
  clpE Streptococcus pneumoniae Rx1

82.048

100

0.82
  clpE Streptococcus pneumoniae D39

82.048

100

0.82
  clpE Streptococcus pneumoniae R6

82.048

100

0.82
  clpE Streptococcus pneumoniae TIGR4

81.915

100

0.819
  clpC Lactococcus lactis subsp. cremoris KW2

76.502

99.601

0.762
  clpC Bacillus subtilis subsp. subtilis str. 168

51.926

86.303

0.448
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.189

87.234

0.403
  clpC Streptococcus pneumoniae Rx1

46.984

83.777

0.394
  clpC Streptococcus pneumoniae D39

46.984

83.777

0.394
  clpC Streptococcus pneumoniae TIGR4

46.825

83.777

0.392
  clpC Streptococcus mutans UA159

45.972

84.176

0.387
  clpC Streptococcus thermophilus LMD-9

46.4

83.112

0.386
  clpC Streptococcus thermophilus LMG 18311

46.08

83.112

0.383