Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   J4854_RS03140 Genome accession   NZ_CP072329
Coordinates   591232..593490 (-) Length   752 a.a.
NCBI ID   WP_200772198.1    Uniprot ID   -
Organism   Streptococcus lactarius strain CCUG 66490     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 586232..598490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4854_RS03120 (J4854_03120) ileS 586647..589439 (+) 2793 WP_200772195.1 isoleucine--tRNA ligase -
  J4854_RS03125 (J4854_03125) - 589640..590074 (+) 435 WP_200772196.1 GNAT family N-acetyltransferase -
  J4854_RS03130 (J4854_03130) - 590156..590458 (-) 303 WP_187540832.1 DUF1827 family protein -
  J4854_RS03135 (J4854_03135) - 590529..590978 (-) 450 WP_200772197.1 NUDIX hydrolase -
  J4854_RS03140 (J4854_03140) clpE 591232..593490 (-) 2259 WP_200772198.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  J4854_RS03145 (J4854_03145) - 593742..593972 (+) 231 WP_187540835.1 DUF1797 family protein -
  J4854_RS03150 (J4854_03150) - 594140..594991 (+) 852 WP_200772199.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  J4854_RS03155 (J4854_03155) - 595008..595781 (+) 774 WP_200772200.1 HAD hydrolase family protein -
  J4854_RS03160 (J4854_03160) - 595834..596682 (+) 849 WP_200772201.1 NAD(P)H-hydrate dehydratase -
  J4854_RS03165 (J4854_03165) xseA 596947..598287 (+) 1341 WP_200772202.1 exodeoxyribonuclease VII large subunit -
  J4854_RS03170 (J4854_03170) - 598265..598477 (+) 213 WP_200772203.1 exodeoxyribonuclease VII small subunit -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83991.16 Da        Isoelectric Point: 5.1642

>NTDB_id=552040 J4854_RS03140 WP_200772198.1 591232..593490(-) (clpE) [Streptococcus lactarius strain CCUG 66490]
MLCQNCKINESTIHLYTNVNGRQQQVDLCQNCYKIMKTDPNNSFLKGMTQRSQLTGDPFEDFFNNLGNFQGPQEPPTPPT
QSGGGYGNGGYGQNNHRESAPDPRQVRPQKPKGLLEEFGINVTEIARNGNVDPVIGRDEEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPDKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVGAG
SAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKRYEDYHHVHYTD
GAIEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLTFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKYK
EMQKTKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLGSPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLVLL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEANVGFGAAREGRTNSVLGELGNFFSPEFMN
RFDGIIEFQALSKENLLQIVTLMLDEVNHRLAQNEIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLE
NPNEKQLKAVMTSNGHISIKAVHKTTEKASES

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=552040 J4854_RS03140 WP_200772198.1 591232..593490(-) (clpE) [Streptococcus lactarius strain CCUG 66490]
ATGCTTTGTCAAAATTGTAAAATAAATGAATCCACTATCCATTTATACACCAATGTAAATGGTCGCCAGCAGCAAGTGGA
CCTCTGTCAAAATTGCTATAAAATTATGAAAACAGACCCAAATAACAGCTTCTTGAAAGGAATGACCCAACGGAGCCAAC
TCACTGGAGATCCCTTCGAAGATTTTTTCAATAACCTTGGAAACTTCCAGGGCCCTCAAGAACCACCTACACCTCCGACC
CAATCTGGAGGAGGCTATGGAAATGGTGGCTACGGTCAAAACAACCATCGGGAAAGTGCTCCAGATCCACGACAAGTACG
CCCTCAAAAACCAAAAGGTCTTTTAGAGGAATTCGGTATCAATGTCACAGAGATTGCGCGTAACGGCAATGTCGATCCAG
TCATTGGGCGCGACGAAGAAATCATTCGTGTCATTGAAATTCTTAACCGCAGAACCAAGAACAATCCCGTCCTCATTGGA
GAACCGGGTGTTGGTAAAACAGCCGTTGTTGAAGGATTAGCCCAAAAAATTGTGGATGGAGATGTCCCTGATAAACTGCA
AGGAAAAGAAGTCATTCGATTAGATGTTGTCAGCCTTGTCCAAGGTACAGGGATCCGAGGCCAGTTTGAAGAACGCATGC
AAAAATTGATGGAAGAAATTCGTCAACGTCAAGACGTCATTCTCTTCATTGATGAAATCCATGAGATTGTCGGAGCTGGT
TCTGCCGGTGATGGCAATATGGATGCCGGAAATATCCTCAAACCTGCCCTCGCTCGTGGTGAATTGCAACTAGTTGGGGC
TACTACTCTTAATGAGTACCGGATCATTGAAAAGGATGCTGCCCTGGAACGTCGGATGCAGCCTGTTAAGGTCGATGAGC
CAACGGTAGAGGAAACCATTACCATTCTTAAAGGGATCCAAAAAAGATACGAAGATTATCACCACGTTCACTATACTGAC
GGAGCCATCGAAGCTGCGGCTACTCTTTCCAACCGTTATATTCAAGACCGCTTCCTACCAGACAAGGCTATTGACTTGCT
AGACGAAGCTGGCTCTAAGATGAACTTAACTTTGACCTTTGTAGACCCTAAGGTCATTGATCAACGCTTGATTGAAGCTG
AAAATCTCAAAGCGCAAGCAACTCGCGACGAAGATTTTGAAAAAGCAGCCTACTTCCGTGACCAGATTGCTAAGTATAAG
GAAATGCAAAAGACTAAGGTAACGGATCAAGACACTCCTATTATTAGCGAAAAGACGATTGAGCATATCATTGAGCAAAA
AACCAATATTCCAGTTGGCGATTTGAAAGAAAAAGAACAATCACAACTCATCCACCTAGCAGAGGATCTCAAGTCTCATG
TTATTGGACAAGATGATGCAGTGGATAAGATTGCCAAGGCGATCCGTCGGAACCGTGTCGGTCTAGGGTCTCCTAATCGT
CCAATTGGTAGTTTCCTCTTTGTTGGTCCGACAGGCGTCGGAAAGACCGAGCTTTCGAAGCAACTAGCTATCGAACTCTT
TGGTTCTGCGGACAGCATGATTCGTTTTGATATGAGTGAATACATGGAAAAACACAGCGTTGCCAAACTCGTCGGTGCTC
CTCCAGGATACGTTGGCTACGATGAAGCTGGACAATTGACTGAGAAAGTGCGGCGAAACCCCTACTCTCTCGTTTTGTTA
GATGAAATCGAAAAAGCCCATCCAGATGTCATGCACATGTTCCTCCAAGTCTTGGATGACGGCCGTTTGACAGATGGTCA
AGGTCGCACTGTCAGCTTTAAAGATACCATTATCATTATGACCTCCAATGCTGGCACAGGAAAGACAGAGGCAAATGTCG
GCTTCGGAGCAGCGCGCGAAGGGCGCACCAACTCTGTGCTTGGAGAACTCGGTAACTTCTTTAGCCCTGAATTTATGAAC
CGTTTTGATGGCATCATTGAGTTCCAAGCTCTATCAAAAGAAAACCTTCTTCAAATTGTTACCCTTATGTTAGACGAAGT
CAATCATCGTCTCGCGCAAAACGAGATTCATCTGGACGTGACAGAGAAGGTCAAGGAAAAACTGGTTGACCTTGGATACG
ATCCAAAAATGGGTGCACGCCCACTCCGTCGTACCATTCAAGACTATATCGAAGATGCGATTACCGACTACTACCTTGAA
AATCCAAATGAAAAACAACTAAAGGCCGTTATGACCAGCAATGGGCATATCAGTATCAAAGCCGTTCATAAAACGACCGA
AAAAGCATCAGAATCCTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(295-392)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(651-724)

ATPase family associated with various cellular activities (AAA) (AAA)

(157-276)

AAA domain (Cdc48 subfamily) (AAA_2)

(480-643)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

87.766

100

0.878
  clpE Streptococcus pneumoniae D39

87.766

100

0.878
  clpE Streptococcus pneumoniae R6

87.766

100

0.878
  clpE Streptococcus pneumoniae TIGR4

87.633

100

0.876
  clpE Streptococcus mutans UA159

83.201

100

0.836
  clpC Lactococcus lactis subsp. cremoris KW2

75.297

100

0.758
  clpC Bacillus subtilis subsp. subtilis str. 168

52.923

86.436

0.457
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.086

86.702

0.408
  clpC Streptococcus pneumoniae Rx1

47.987

82.58

0.396
  clpC Streptococcus pneumoniae D39

47.987

82.58

0.396
  clpC Streptococcus pneumoniae TIGR4

47.826

82.58

0.395
  clpC Streptococcus thermophilus LMD-9

47.191

82.846

0.391
  clpC Streptococcus thermophilus LMG 18311

46.87

82.846

0.388
  clpC Streptococcus mutans UA159

46.338

83.511

0.387