Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   J6L97_RS09760 Genome accession   NZ_CP072197
Coordinates   2004031..2005827 (+) Length   598 a.a.
NCBI ID   WP_057726344.1    Uniprot ID   A0A5M9Z584
Organism   Lactobacillus crispatus strain ATCC 33820     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1999031..2010827
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J6L97_RS09730 (J6L97_09730) - 1999932..2000309 (-) 378 WP_054832736.1 hypothetical protein -
  J6L97_RS09735 (J6L97_09735) - 2000454..2001005 (+) 552 WP_005722451.1 GNAT family protein -
  J6L97_RS09740 (J6L97_09740) - 2001119..2001265 (+) 147 WP_005718178.1 hypothetical protein -
  J6L97_RS09745 (J6L97_09745) - 2001305..2001877 (+) 573 WP_225907786.1 PBECR4 domain-containing protein -
  J6L97_RS09750 (J6L97_09750) - 2001874..2002563 (-) 690 WP_057726348.1 DUF554 domain-containing protein -
  J6L97_RS09755 (J6L97_09755) - 2002630..2003865 (-) 1236 WP_057726346.1 LCP family protein -
  J6L97_RS09760 (J6L97_09760) pepF 2004031..2005827 (+) 1797 WP_057726344.1 oligoendopeptidase F Regulator
  J6L97_RS09765 (J6L97_09765) - 2006228..2006443 (+) 216 WP_005723825.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
  J6L97_RS09770 (J6L97_09770) - 2006447..2006857 (+) 411 WP_057726342.1 type II toxin-antitoxin system death-on-curing family toxin -
  J6L97_RS09775 (J6L97_09775) - 2006921..2007193 (-) 273 WP_013086917.1 bacteriocin immunity protein -
  J6L97_RS09780 (J6L97_09780) - 2007271..2008068 (-) 798 WP_223876341.1 CPBP family intramembrane glutamic endopeptidase -
  J6L97_RS09785 (J6L97_09785) - 2008084..2008281 (-) 198 WP_013086919.1 helix-turn-helix transcriptional regulator -
  J6L97_RS09790 (J6L97_09790) - 2008278..2008757 (-) 480 WP_013086920.1 hypothetical protein -
  J6L97_RS09795 (J6L97_09795) - 2009419..2010537 (+) 1119 WP_057726340.1 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -

Sequence

Protein


Download         Length: 598 a.a.        Molecular weight: 68094.91 Da        Isoelectric Point: 4.7278

>NTDB_id=551102 J6L97_RS09760 WP_057726344.1 2004031..2005827(+) (pepF) [Lactobacillus crispatus strain ATCC 33820]
MAIPTRNEVPEELKWDLTRIFKNDDEWEQAYAAAQEKVAKLAELKGTLAKSGKNLYESLTKILAVKRDVENIYVYATMSS
DVDTSNSHYLGYVSRVQSLANQFEAATSFINPEILSIPSDKLEQFKQAEPRLKDYAHYLETITNKRPHTLPAEQEKLIAD
AGDALSVSENTFNVLTNSDMEYGYVQDDDGNMEQLSDGLYSLLIQSQNRDVRKGAFDTLYATYGQFQNSLASTLSGVVKK
HNYNARVHKYNSAREAALADNGVHVAVYDTLIQEVDSHLDLLHRYVALRKKILGMKDLQMWDMYVPLTGRPSLSYNFEEA
KETAKKALAPLGEDYLKHVDYIFNNRVIDPIESKNKVTGAYSGGAYDTDPYELLNWEDNIDSLYTLVHETGHSVHSWYTR
NTQPYVYGDYPIFVAEIASTTNENILTEYFLDHITDSKTRAFILNYYLDSFKGTLFRQTQFAVFEQFLHEADAKGEPLTA
DTLDDVYGQINQHYYGDSVEPGGDIALEWSRIPHFYYNFYVYQYATGFAAATALANKVVHGTPAERDAYLGFLKAGSSDY
PTEIMKRAGVDMTKPDYLEDAFKTFEKRLNEFENLIEK

Nucleotide


Download         Length: 1797 bp        

>NTDB_id=551102 J6L97_RS09760 WP_057726344.1 2004031..2005827(+) (pepF) [Lactobacillus crispatus strain ATCC 33820]
ATGGCAATTCCAACTAGAAACGAAGTCCCTGAAGAGCTTAAATGGGACTTAACCCGTATTTTTAAAAATGACGATGAATG
GGAGCAAGCTTATGCAGCTGCACAAGAAAAAGTGGCTAAACTTGCTGAATTAAAAGGTACACTAGCTAAATCAGGCAAGA
ACCTGTACGAGAGCTTAACCAAAATCTTAGCTGTTAAACGTGATGTGGAAAATATCTACGTTTACGCTACCATGTCCAGC
GATGTTGATACTTCTAATTCGCACTATCTCGGCTATGTCAGCCGGGTACAAAGTTTGGCTAACCAGTTTGAGGCTGCAAC
AAGTTTTATTAATCCTGAAATCTTGAGTATCCCTAGTGATAAGCTTGAGCAATTTAAGCAAGCTGAACCTAGATTAAAGG
ATTACGCACACTATCTTGAAACAATTACTAACAAGCGTCCTCATACATTACCTGCTGAGCAAGAAAAATTGATCGCCGAT
GCTGGGGATGCTTTAAGTGTTTCTGAAAATACCTTTAACGTCTTGACCAACTCCGACATGGAATACGGTTACGTTCAAGA
CGATGACGGCAATATGGAACAATTATCAGATGGCCTTTATTCTTTGCTGATCCAATCCCAAAATCGTGATGTCAGAAAAG
GTGCTTTTGATACACTTTATGCCACTTATGGACAGTTCCAAAATTCCTTGGCTTCAACTTTGTCTGGCGTTGTAAAAAAG
CACAACTATAACGCACGTGTGCACAAGTATAATTCAGCTCGTGAAGCTGCTTTAGCCGATAATGGCGTACACGTAGCAGT
TTATGACACTTTAATCCAGGAAGTTGATTCACACCTAGACTTACTTCACCGTTATGTTGCGCTACGTAAAAAGATCTTAG
GCATGAAGGATCTGCAAATGTGGGACATGTATGTGCCACTAACTGGAAGACCTTCTCTTTCATACAATTTCGAAGAAGCA
AAAGAGACAGCAAAAAAGGCTTTGGCTCCACTTGGTGAAGACTACTTGAAGCATGTTGACTATATTTTTAATAATCGTGT
CATCGACCCAATAGAATCTAAAAATAAAGTAACTGGTGCCTACTCTGGTGGTGCTTATGATACCGATCCTTATGAGTTGC
TCAACTGGGAAGATAACATCGATTCACTTTATACTTTAGTCCACGAAACTGGTCACTCCGTTCACTCCTGGTACACTCGC
AATACTCAACCTTACGTTTACGGCGACTATCCAATCTTTGTGGCTGAAATTGCTTCAACTACTAATGAAAATATTTTGAC
CGAATATTTCTTAGACCACATTACCGATTCTAAGACGCGGGCCTTTATCTTAAATTACTACCTTGATTCATTTAAAGGCA
CTTTATTCCGTCAAACTCAATTTGCCGTGTTTGAACAATTCTTGCACGAAGCCGATGCTAAGGGAGAACCACTGACTGCT
GACACTTTAGACGATGTTTATGGTCAAATTAATCAGCATTATTACGGCGATAGCGTTGAACCAGGCGGCGATATTGCCCT
TGAATGGTCACGAATTCCACACTTCTACTACAATTTCTATGTGTACCAATATGCGACTGGCTTTGCGGCTGCAACGGCAT
TAGCCAACAAGGTGGTTCATGGAACGCCTGCTGAGAGGGATGCCTACCTTGGCTTCCTTAAAGCTGGTTCAAGTGATTAC
CCAACTGAGATCATGAAGCGTGCTGGCGTGGACATGACCAAGCCAGACTACTTGGAGGATGCATTCAAGACTTTTGAAAA
GCGGTTGAATGAATTTGAGAATTTGATTGAGAAGTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(113-181)

Peptidase family M3 (Peptidase_M3)

(203-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5M9Z584

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

51.265

99.164

0.508