Detailed information NTG0055075

Bioinformatically predicted

Overview

• Name: uvrA
• Type: Machinery gene
• Locus tag: ANG_RS02435
• Genome accession: NZ_AP013072
• Coordinates: 461055..463880 (+)
• Length: 941 a.a.
• NCBI ID: WP_003037804.1
• Uniprot ID: I0SA28
• Organism: Streptococcus anginosus subsp. whileyi MAS624
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 456055..468880

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ANG_RS02405 (ANG_0472)	-	456725..457768 (-)	1044	WP_025271617.1	bifunctional glycosyltransferase family 2/GtrA family protein	-
ANG_RS02410 (ANG_0473)	rpsF	458045..458335 (+)	291	WP_003026325.1	30S ribosomal protein S6	-
ANG_RS02415 (ANG_0474)	ssb	458348..458839 (+)	492	WP_003026323.1	single-stranded DNA-binding protein	Machinery gene
ANG_RS02420 (ANG_0475)	rpsR	458876..459115 (+)	240	WP_000068664.1	30S ribosomal protein S18	-
ANG_RS02425 (ANG_0476)	-	459295..459972 (-)	678	WP_003037754.1	DUF1129 domain-containing protein	-
ANG_RS02430 (ANG_0477)	-	459988..460932 (-)	945	WP_003030529.1	magnesium transporter CorA family protein	-
ANG_RS02435 (ANG_0478)	uvrA	461055..463880 (+)	2826	WP_003037804.1	excinuclease ABC subunit UvrA	Machinery gene
ANG_RS02440 (ANG_0479)	-	463918..464673 (-)	756	WP_020999818.1	hypothetical protein	-
ANG_RS02445 (ANG_0480)	-	464832..465893 (+)	1062	WP_025271618.1	M24 family metallopeptidase	-
ANG_RS02450 (ANG_0481)	efp	465952..466512 (+)	561	WP_003037772.1	elongation factor P	-
ANG_RS02455 (ANG_0482)	-	466623..467012 (+)	390	WP_003037725.1	Asp23/Gls24 family envelope stress response protein	-
ANG_RS02460 (ANG_0483)	nusB	467005..467430 (+)	426	WP_003037723.1	transcription antitermination factor NusB	-
ANG_RS02465 (ANG_0484)	comR/comR2	467647..468120 (+)	474	WP_020999816.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 941 a.a.
• Molecular weight: 103840.14 Da
• Isoelectric Point: 6.4507

>NTDB_id=55075 ANG_RS02435 WP_003037804.1 461055..463880(+) (uvrA) [Streptococcus anginosus subsp. whileyi MAS624]
MQDKIIIHGARAHNLKNIDVTIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTATEINDYLRLLYARVGTPYCINGHGAITASAVEQIVNQVLELPERQRLQILAPVIRKKK
GQHKTIFEKIQKDGYVRVRADGDVYDVTEVPDLSKTKKHDIEVVVDRIVIKDGVRSRLFDSIEAALRIADGYVVIDTMDG
KELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCPDCDGLGVKLEVDLDMVVPDSSKTLREGALAPWNPISSNYYPQML
EQAMTEFGIDMDKPFEDLTEDERQLIFFGSEGREFHFHYENEFGGVRDIDIPFEGVVTNINRRYHETNSDFTRTQMRLYM
NELTCASCHGYRLNPQALSVKVGGEGGLNIGQVSDLSIADHLELISHLTLTENEVAIATPIIKEIRDRLTFLHNVGLNYL
TLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNNRLIASLKKMRDLGNTLIVVEHDEDTMREADWLI
DVGPGAGVFGGEIVAAGTPDQVAKNKKSITGQYLSGKREIPLPLERRVGNGLFIEVTGAREHNLQNITARFPLGKFIAVT
GVSGSGKSTLVNSILKKAIAQKLNRNSDKPGKFKKISGIEHIDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAKTNE
AKIHGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGTRYNSETLEVHYKDKNIAQVLDMTVNDAVEFF
KHIPKIERKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTEDIAKLLQVLSRFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGIGGGTIIATGTPEEVAANSASYTGQYLKGKLK

Nucleotide

• Length: 2826 bp

>NTDB_id=55075 ANG_RS02435 WP_003037804.1 461055..463880(+) (uvrA) [Streptococcus anginosus subsp. whileyi MAS624]
ATGCAGGATAAAATTATCATTCATGGAGCGCGAGCTCATAATCTAAAAAATATTGATGTCACGATTCCGCGGGACAAACT
GGTTGTCGTGACTGGTTTGTCTGGTTCGGGAAAGTCTAGCCTCGCTTTTGACACTCTCTATGCAGAAGGACAACGGCGCT
ATGTAGAAAGTTTGTCTGCCTATGCCCGTCAATTTTTGGGCAATATGGAAAAACCAGATGTGGATTCAATTGACGGACTT
AGTCCAGCTATTTCTATTGACCAAAAAACGACCAGCAAGAATCCACGGTCAACGGTTGGAACAGCAACAGAAATCAACGA
TTACCTTCGTTTGCTCTATGCGCGTGTGGGTACTCCTTACTGTATCAATGGGCATGGAGCTATTACTGCTTCTGCTGTGG
AACAAATCGTCAATCAAGTTTTGGAATTACCCGAACGTCAGCGATTACAAATTCTAGCGCCAGTTATCCGTAAGAAAAAA
GGACAGCACAAGACAATCTTTGAAAAAATCCAAAAAGATGGGTATGTGCGAGTGCGCGCGGACGGGGACGTTTATGATGT
AACCGAAGTCCCAGATCTTTCTAAAACGAAAAAGCACGATATCGAAGTAGTGGTGGACCGAATTGTTATTAAGGACGGTG
TACGCAGTCGGTTGTTTGATTCGATTGAAGCAGCCTTAAGAATTGCGGACGGTTACGTGGTGATCGATACGATGGATGGC
AAGGAATTACTCTTTTCCGAGCATTATGCTTGTCCAGTCTGTGGCTTTACGGTACCTGAGTTGGAGCCTCGCCTCTTTTC
TTTTAATGCACCATTCGGCTCTTGTCCTGATTGTGACGGTCTGGGTGTGAAGTTGGAAGTGGACTTGGATATGGTGGTTC
CTGACAGTAGTAAAACCTTGCGGGAAGGCGCCTTAGCTCCGTGGAATCCTATTTCTTCAAATTACTATCCTCAAATGCTA
GAGCAGGCAATGACGGAATTTGGTATTGATATGGATAAGCCATTTGAGGACCTGACAGAAGACGAGCGGCAGCTGATTTT
CTTTGGCTCTGAAGGACGAGAATTTCATTTCCATTATGAAAATGAATTTGGTGGTGTGCGAGATATTGACATTCCTTTTG
AAGGCGTCGTGACCAATATCAACCGTCGCTACCATGAGACCAATAGTGATTTCACCCGTACCCAGATGCGGCTTTATATG
AATGAGTTGACTTGTGCGAGTTGCCATGGTTATCGATTGAATCCACAAGCCTTGTCTGTTAAAGTGGGGGGTGAAGGTGG
TCTTAATATTGGCCAAGTATCTGATTTGTCTATTGCAGATCATTTAGAATTGATTTCTCATCTGACATTGACTGAAAACG
AAGTGGCCATTGCAACACCGATTATTAAAGAAATTCGCGATCGCTTGACTTTTCTTCATAATGTCGGACTTAATTATCTA
ACTCTGTCTCGGTCTGCGGGAACATTGTCGGGTGGGGAGAGTCAGCGGATCCGCTTGGCGACTCAAATCGGCTCTAATCT
CAGCGGTGTTCTTTATATCTTAGATGAGCCTTCTATCGGTCTTCATCAGCGGGATAACAATCGCTTGATTGCCAGTCTCA
AAAAAATGCGTGATTTGGGTAATACCCTCATTGTGGTTGAACATGATGAGGACACCATGCGTGAAGCGGATTGGTTAATT
GATGTTGGACCGGGAGCTGGTGTTTTCGGTGGCGAAATTGTTGCGGCAGGCACACCTGATCAAGTTGCAAAAAACAAGAA
ATCAATTACAGGTCAGTATTTATCGGGCAAACGTGAAATTCCACTGCCATTGGAGCGCCGCGTAGGAAACGGCCTCTTTA
TTGAAGTAACAGGTGCGCGAGAGCACAATTTGCAAAATATCACAGCTCGTTTCCCTCTAGGAAAATTCATTGCTGTGACA
GGTGTTTCTGGTTCCGGAAAGTCTACTCTGGTTAATTCTATTCTCAAAAAAGCAATCGCTCAAAAACTCAATCGTAATTC
AGACAAACCGGGAAAATTTAAAAAGATTTCAGGCATTGAGCATATCGATCGTTTGATTGATATTGACCAGAGCCCGATTG
GACGGACTCCTCGCTCCAATCCTGCCACCTATACTGGGGTTTTCGATGATATTCGTGATCTCTTTGCTAAAACCAACGAA
GCTAAGATTCATGGGTATAAAAAAGGGCGTTTCTCTTTCAATGTGAAGGGGGGGCGCTGCGAGGCCTGCTCTGGGGATGG
GATTATCAAGATTGAGATGCATTTTCTACCAGATGTCTACGTTCCTTGTGAAGTTTGCCACGGCACTCGCTACAATAGTG
AAACTCTGGAAGTGCATTATAAGGATAAGAATATCGCACAAGTTTTGGATATGACGGTCAATGATGCAGTGGAATTTTTT
AAGCATATTCCTAAAATTGAGCGGAAACTTCAGACCATCAAAGACGTAGGACTAGGATATGTAACGTTAGGACAACCTGC
CACAACTCTGTCTGGTGGGGAGGCGCAGCGGATGAAACTAGCCAGCGAACTTCACAAGCGCTCAACAGGTAAGTCTTTCT
ATATTCTGGATGAACCAACTACAGGTCTGCACACGGAGGATATTGCGAAACTTCTCCAAGTGCTATCACGTTTTGTAGAT
GATGGCAACACGGTTCTCGTCATCGAGCATAATTTGGACGTTATTAAGACGGCTGATCACATTATTGACCTTGGGCCAGA
AGGTGGTATTGGTGGAGGTACTATTATTGCAACTGGTACACCGGAAGAAGTAGCTGCAAACTCTGCTAGCTATACTGGCC
AGTATCTAAAAGGAAAGTTAAAATAA

Domains

Predicted by InterProScan.

• UvrA DNA-binding domain (UvrA_DNA-bind) (288-396)

• UvrA interaction domain (UvrA_inter) (133-238)

• ABC transporter (ABC_tran) (624-860)

3D structure

• AlphaFold DB: I0SA28

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrA	Streptococcus pneumoniae R6	89.362	99.894	0.893
uvrA	Streptococcus pneumoniae TIGR4	89.362	99.894	0.893
uvrA	Streptococcus pneumoniae D39	89.362	99.894	0.893