Detailed information NTG0055062

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ANG_RS01115
• Genome accession: NZ_AP013072
• Coordinates: 212234..214795 (+)
• Length: 853 a.a.
• NCBI ID: WP_020999883.1
• Uniprot ID: -
• Organism: Streptococcus anginosus subsp. whileyi MAS624
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 207234..219795

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ANG_RS01095 (ANG_0196)	-	208536..209045 (+)	510	WP_003027812.1	hypothetical protein	-
ANG_RS01100 (ANG_0197)	nrdI	209121..209576 (+)	456	WP_020999884.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
ANG_RS01105 (ANG_0198)	argS	209631..211319 (-)	1689	WP_003038336.1	arginine--tRNA ligase	-
ANG_RS01110 (ANG_0199)	argR	211423..211863 (+)	441	WP_003038414.1	arginine repressor	-
ANG_RS01115 (ANG_0200)	hexA	212234..214795 (+)	2562	WP_020999883.1	DNA mismatch repair protein MutS	Machinery gene
ANG_RS01120 (ANG_0201)	-	214983..215441 (-)	459	WP_003038399.1	DUF3021 domain-containing protein	-
ANG_RS01125 (ANG_0202)	-	215438..215878 (-)	441	WP_003032335.1	LytTR family DNA-binding domain-containing protein	-
ANG_RS01130 (ANG_0203)	-	216430..216810 (-)	381	WP_003038371.1	type II toxin-antitoxin system HicB family antitoxin	-
ANG_RS01135 (ANG_0204)	-	216846..217037 (-)	192	WP_003038349.1	type II toxin-antitoxin system HicA family toxin	-
ANG_RS11270	-	217173..217286 (-)	114	Protein_201	phage terminase small subunit P27 family	-
ANG_RS01140 (ANG_0205)	-	217568..218008 (-)	441	WP_003038422.1	ArpU family phage packaging/lysis transcriptional regulator	-
ANG_RS01145 (ANG_0206)	-	218257..219108 (-)	852	WP_020999881.1	ATP-binding protein	-

Sequence

Protein

• Length: 853 a.a.
• Molecular weight: 96034.63 Da
• Isoelectric Point: 5.0002

>NTDB_id=55062 ANG_RS01115 WP_020999883.1 212234..214795(+) (hexA) [Streptococcus anginosus subsp. whileyi MAS624]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDATNAAQILEIALTSRNKNSENPIPMAGVPYHSVQQYIDVLI
EAGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVALDKLSGIYGLAYMDVGTGEFQVTSLSDFNI
VCGEIRNLRAREVVLGYELPEMERQVLETQMTLLLSQVETTFDDVQLLGKDLSPLEHQVAGKLLQYVHKTQLRELSHLKQ
VHHYEIKDFLQMDYSTMASLDLTENARTGKKHGSLYWLMDDTKTAMGTRLLRAWIQRPLIDKERIVKRQDVVQVFLDHFF
ERSDLSDTLKGVYDIERLASRVSFGKTNPKDLLQLAATLSHVPQIKGILKGIDSPVLEDLIAKLDEIPELASLIQSAISP
DAPNVITEGNIIKTGFDETLDKYRVVMRDGTSWIADIEAKEREASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTLATVDVLQSFAAVAEKQHFVRPEFI
EQRSIQIDKGRHAVVEKVMGAQTYIPNSISMDENVNVQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAESAQLPIFDA
IFTRIGAADDLVSGQSTFMIEMMEANHAISQATENSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TELSTSLTQLENVHVETLEKDGQVTFLHKIEVGPADKSYGIHVAKIAGLPNDLLTRADQILTRLESQANEKSSFGISNTL
PTDAREKNQVAEQMSLFTETTESPILDELRQLDIYNMTPMEVMLAVAEIKKKL

Nucleotide

• Length: 2562 bp

>NTDB_id=55062 ANG_RS01115 WP_020999883.1 212234..214795(+) (hexA) [Streptococcus anginosus subsp. whileyi MAS624]
ATGACAAAAGAAAAACTATCTCCAGGAATGCAACAGTATTTAGATATAAAAAAAGATTATCCAGATGCTTTTTTGTTGTT
TCGCATGGGAGATTTTTATGAATTATTCTATGATGATGCGACCAATGCGGCACAGATTTTAGAGATTGCTCTGACTAGTC
GCAATAAAAACTCGGAAAATCCAATCCCAATGGCAGGAGTTCCTTACCATTCAGTGCAGCAATACATTGATGTTTTAATT
GAAGCAGGCTATAAAGTTGCGATTGCAGAGCAAATGGAAGATCCTAAAAAAGCGGTTGGAGTAGTCAAACGCGAAGTAGT
ACAGGTGATTACGCCGGGGACAGTAGTTGATTCTTCAAAACCAGACAGTCAGAATAACTTTTTAGTGGCTTTGGATAAGC
TGTCAGGTATATATGGACTGGCTTATATGGATGTGGGAACGGGTGAATTTCAGGTCACAAGTCTTAGTGACTTTAACATA
GTCTGTGGAGAAATCCGAAACTTGCGAGCTCGTGAAGTGGTCTTAGGGTATGAATTGCCTGAAATGGAGCGCCAAGTATT
GGAGACTCAAATGACTCTCCTTTTATCGCAAGTAGAAACTACATTTGATGATGTTCAGCTACTAGGAAAGGACTTGTCAC
CGCTAGAGCACCAAGTAGCTGGAAAGTTATTACAGTATGTTCATAAAACGCAGCTACGTGAGCTTAGTCATTTGAAACAA
GTTCATCATTATGAAATCAAAGATTTCTTGCAGATGGACTACTCAACTATGGCAAGTCTGGATTTAACAGAGAATGCTCG
GACAGGAAAGAAGCACGGGAGCCTTTATTGGCTGATGGATGATACCAAGACAGCTATGGGAACACGATTGTTGAGAGCGT
GGATTCAACGTCCGTTGATTGATAAAGAGCGAATCGTCAAGCGGCAGGATGTAGTGCAAGTCTTTTTAGATCATTTCTTT
GAGCGCAGTGACTTATCAGACACTCTCAAAGGAGTGTATGATATTGAGCGTTTAGCCAGTCGGGTTTCGTTTGGCAAGAC
CAATCCAAAAGATTTATTACAACTTGCTGCGACATTGAGTCATGTACCACAAATTAAGGGAATCTTAAAAGGAATTGACA
GCCCAGTTTTGGAAGATTTGATTGCCAAATTGGATGAAATTCCTGAACTGGCGTCCTTAATTCAGTCAGCAATTTCGCCG
GATGCTCCAAATGTCATTACAGAGGGTAATATTATTAAAACAGGTTTTGATGAAACCTTGGATAAATATCGAGTGGTTAT
GCGAGATGGAACGAGCTGGATTGCAGATATTGAGGCGAAAGAAAGAGAAGCTAGTGGAATTAACAACCTGAAGATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTCACCAATTCTCAGCTTGAGCATGTTCCCAGTCATTTTTTCCGCAAGGCA
ACTTTGAAAAATTCGGAGCGTTTTGGTACGGAAGAACTGGCTCGTATTGAAGGTGAGATGTTGGAAGCGCGTGAAAAATC
AGCTAATTTGGAATACGAGATTTTTATGCGCATTCGTGAGGAAGCTGGTAAATATATCAAACGCCTGCAATCCTTGGCGC
AAACTCTGGCAACGGTTGATGTGCTGCAAAGCTTTGCAGCTGTAGCAGAAAAGCAACATTTTGTGAGACCAGAATTTATT
GAGCAGCGCTCTATCCAAATTGATAAAGGGCGGCATGCGGTCGTAGAAAAAGTTATGGGTGCACAAACCTACATTCCTAA
TAGCATTTCAATGGATGAGAATGTTAATGTTCAGCTAATTACAGGCCCAAATATGAGTGGGAAGTCAACTTATATGCGGC
AGTTAGCGATTATTGTGATTATGGCTCAAATGGGCTCTTATGTTTCAGCCGAAAGTGCCCAATTGCCGATTTTTGATGCA
ATCTTTACTCGAATTGGTGCAGCTGATGACTTGGTTTCTGGACAATCAACCTTTATGATTGAAATGATGGAAGCGAACCA
TGCTATTTCTCAAGCAACAGAAAATTCACTCATTCTTTTTGATGAGTTAGGAAGAGGAACAGCTACCTATGATGGCATGG
CGCTTGCTCAAGCTATTATTGAGTATATTCACAATCGGACAGGAGCCAAGACACTTTTTGCGACTCACTATCACGAGTTG
ACAGAACTGTCAACTAGCTTGACACAACTAGAAAATGTCCATGTAGAAACCCTAGAAAAAGATGGTCAAGTAACATTTCT
TCATAAGATTGAGGTTGGACCTGCTGATAAATCTTATGGGATTCATGTAGCAAAAATTGCAGGTTTGCCAAATGATTTGT
TGACAAGAGCGGATCAAATATTGACACGATTAGAAAGCCAAGCAAATGAGAAGTCATCTTTTGGCATCTCTAATACATTG
CCTACGGATGCTCGTGAAAAAAATCAAGTGGCTGAGCAGATGTCTTTATTTACAGAAACAACTGAATCACCTATTTTAGA
CGAGTTGCGCCAGTTGGACATTTATAATATGACCCCAATGGAAGTGATGTTGGCTGTGGCAGAGATAAAGAAGAAACTTT
AA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain III (MutS_III) (255-546)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	76.202	100	0.762
mutS	Pseudomonas stutzeri strain ATCC 17587	36.269	100	0.367