Detailed information NTG0550546

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: J5M87_RS07140
• Genome accession: NZ_CP072115
• Coordinates: 1508718..1509767 (-)
• Length: 349 a.a.
• NCBI ID: WP_154608494.1
• Uniprot ID: A0A6I4RIY2
• Organism: Streptococcus zhangguiae strain zg-86
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1503718..1514767

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J5M87_RS07120 (J5M87_07120)	trpB	1504331..1505521 (-)	1191	WP_154608490.1	tryptophan synthase subunit beta	-
J5M87_RS07125 (J5M87_07125)	-	1506050..1506565 (-)	516	WP_154608491.1	VanZ family protein	-
J5M87_RS07130 (J5M87_07130)	rlmN	1506562..1507674 (-)	1113	WP_154608492.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
J5M87_RS07135 (J5M87_07135)	-	1507682..1508248 (-)	567	WP_154608493.1	YutD-like domain-containing protein	-
J5M87_RS07140 (J5M87_07140)	sepM	1508718..1509767 (-)	1050	WP_154608494.1	SepM family pheromone-processing serine protease	Regulator
J5M87_RS07145 (J5M87_07145)	coaD	1509754..1510242 (-)	489	WP_154608495.1	pantetheine-phosphate adenylyltransferase	-
J5M87_RS07150 (J5M87_07150)	rsmD	1510232..1510771 (-)	540	WP_154608496.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
J5M87_RS07155 (J5M87_07155)	-	1511191..1511574 (-)	384	WP_154608497.1	rhodanese-like domain-containing protein	-
J5M87_RS07160 (J5M87_07160)	-	1511578..1511790 (-)	213	WP_154608498.1	YqgQ family protein	-
J5M87_RS07165 (J5M87_07165)	-	1511844..1512023 (-)	180	WP_154608499.1	hypothetical protein	-
J5M87_RS07170 (J5M87_07170)	-	1512671..1513273 (-)	603	WP_154608500.1	response regulator transcription factor	-
J5M87_RS07175 (J5M87_07175)	-	1513254..1514369 (-)	1116	WP_154608501.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37628.16 Da
• Isoelectric Point: 5.9473

>NTDB_id=550546 J5M87_RS07140 WP_154608494.1 1508718..1509767(-) (sepM) [Streptococcus zhangguiae strain zg-86]
MKKNKKLLLILSIVLSTVLLWVAFLFPLPYYVESPGGASDIRSVLTVAGKKDDKPGSYNFVYVQVKPATAVQLLLAALDS
HSDIIPKQELAGGANSEEFYRISQFYMETSQNMAKYQGLKLAKKDTSLEFFGVYVLNVTEDSTFKQILNIADTVVSVNGK
TFKSSPELIDYVSGLTLGSDVEVGYLSSGKELTAKGKIIKLENGKNGIGIGLVDHTEVKSSEKIDFQTGNIGGPSAGLMF
TLAIYTQLADPDLRDGRVIAGTGTIEQDGSVGDIGGADKKVLSAAKAGASIFFAPNNPVDPEILKQKPDAKTNYEEAMEA
VKKDKLTIQVVPVTNVQEAIDYLKKTKGQ

Nucleotide

• Length: 1050 bp

>NTDB_id=550546 J5M87_RS07140 WP_154608494.1 1508718..1509767(-) (sepM) [Streptococcus zhangguiae strain zg-86]
ATGAAAAAAAATAAAAAATTACTTCTGATTCTCTCGATAGTTCTCTCGACTGTCCTTTTGTGGGTAGCCTTTCTCTTTCC
ACTTCCCTACTATGTCGAAAGTCCAGGTGGAGCTTCTGATATTCGAAGTGTCTTGACCGTGGCTGGGAAAAAAGACGACA
AACCGGGTTCTTATAATTTTGTCTATGTTCAAGTCAAACCTGCTACTGCTGTTCAACTCTTGCTTGCTGCCCTAGATTCT
CATTCGGACATCATTCCAAAGCAAGAATTGGCAGGTGGCGCAAATAGCGAGGAGTTTTACCGGATTAGTCAATTTTATAT
GGAAACCTCTCAAAATATGGCGAAATATCAAGGTTTAAAACTAGCTAAGAAAGACACCTCTTTGGAGTTCTTTGGAGTCT
ATGTTCTCAATGTGACGGAAGATTCGACTTTTAAGCAGATTTTGAATATTGCAGACACCGTTGTGAGTGTGAATGGCAAG
ACCTTTAAGAGTTCTCCTGAACTCATTGACTATGTCAGTGGTTTAACATTAGGCAGCGATGTTGAGGTTGGTTATCTCAG
TTCTGGTAAGGAATTGACCGCCAAAGGAAAAATTATTAAACTCGAAAACGGAAAAAATGGTATTGGCATTGGCCTAGTTG
ACCATACCGAGGTTAAAAGTAGTGAAAAGATTGATTTCCAAACTGGTAATATCGGTGGTCCGAGTGCAGGCTTGATGTTT
ACACTTGCCATTTACACACAGTTAGCTGATCCTGATTTGCGAGACGGACGAGTAATTGCAGGTACTGGAACGATTGAGCA
AGACGGTTCTGTCGGTGATATTGGTGGAGCGGATAAGAAGGTCTTGTCTGCTGCAAAAGCTGGGGCAAGTATCTTCTTTG
CTCCCAATAATCCTGTTGATCCTGAAATCTTAAAACAAAAACCAGATGCTAAAACGAACTATGAAGAAGCAATGGAAGCT
GTGAAAAAAGATAAATTGACTATTCAGGTTGTTCCAGTGACCAATGTCCAGGAAGCGATTGATTATCTGAAAAAAACCAA
GGGCCAGTAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-297)

• PDZ domain (PDZ_2) (132-195)

3D structure

• AlphaFold DB: A0A6I4RIY2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.58	98.854	0.599