Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   J5Z97_RS06400 Genome accession   NZ_CP072112
Coordinates   1257544..1258581 (-) Length   345 a.a.
NCBI ID   WP_010922499.1    Uniprot ID   A0A4U9I5V9
Organism   Streptococcus pyogenes strain M08500     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1252544..1263581
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5Z97_RS06380 (J5Z97_06380) - 1253282..1253908 (+) 627 WP_002983834.1 A24 family peptidase -
  J5Z97_RS06385 (J5Z97_06385) rlmN 1253989..1255068 (-) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  J5Z97_RS06390 (J5Z97_06390) - 1255072..1255692 (-) 621 WP_063662286.1 YutD family protein -
  J5Z97_RS06395 (J5Z97_06395) - 1256141..1257118 (-) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  J5Z97_RS06400 (J5Z97_06400) sepM 1257544..1258581 (-) 1038 WP_010922499.1 SepM family pheromone-processing serine protease Regulator
  J5Z97_RS06405 (J5Z97_06405) coaD 1258568..1259059 (-) 492 WP_208769252.1 pantetheine-phosphate adenylyltransferase -
  J5Z97_RS06410 (J5Z97_06410) rsmD 1259049..1259588 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  J5Z97_RS06415 (J5Z97_06415) asnA 1259711..1260703 (-) 993 WP_023611792.1 aspartate--ammonia ligase -
  J5Z97_RS06420 (J5Z97_06420) arcC 1261016..1261966 (-) 951 WP_023611802.1 carbamate kinase -
  J5Z97_RS06425 (J5Z97_06425) - 1261986..1263317 (-) 1332 WP_063662292.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37541.24 Da        Isoelectric Point: 9.6692

>NTDB_id=550487 J5Z97_RS06400 WP_010922499.1 1257544..1258581(-) (sepM) [Streptococcus pyogenes strain M08500]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=550487 J5Z97_RS06400 WP_010922499.1 1257544..1258581(-) (sepM) [Streptococcus pyogenes strain M08500]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGTATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9I5V9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

69.275

100

0.693