Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | J5Z97_RS01415 | Genome accession | NZ_CP072112 |
| Coordinates | 244947..246308 (+) | Length | 453 a.a. |
| NCBI ID | WP_002986109.1 | Uniprot ID | A0A4Q1R665 |
| Organism | Streptococcus pyogenes strain M08500 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 195641..244866 | 244947..246308 | flank | 81 |
Gene organization within MGE regions
Location: 195641..246308
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J5Z97_RS01105 (J5Z97_01105) | - | 195641..196873 (-) | 1233 | WP_009880892.1 | transglutaminase domain-containing protein | - |
| J5Z97_RS01115 (J5Z97_01115) | - | 197249..198391 (-) | 1143 | WP_180383156.1 | site-specific integrase | - |
| J5Z97_RS01120 (J5Z97_01120) | - | 198518..199051 (-) | 534 | WP_085577383.1 | hypothetical protein | - |
| J5Z97_RS01125 (J5Z97_01125) | - | 199063..199443 (-) | 381 | WP_002986288.1 | ImmA/IrrE family metallo-endopeptidase | - |
| J5Z97_RS01130 (J5Z97_01130) | - | 199453..199803 (-) | 351 | WP_136276228.1 | helix-turn-helix transcriptional regulator | - |
| J5Z97_RS01135 (J5Z97_01135) | - | 200113..200328 (+) | 216 | WP_136276230.1 | transcriptional regulator | - |
| J5Z97_RS09345 | - | 200402..200536 (+) | 135 | WP_002986279.1 | hypothetical protein | - |
| J5Z97_RS01140 (J5Z97_01140) | - | 200533..201267 (+) | 735 | WP_115250270.1 | ORF6C domain-containing protein | - |
| J5Z97_RS01145 (J5Z97_01145) | - | 201332..201592 (+) | 261 | WP_002986256.1 | hypothetical protein | - |
| J5Z97_RS01150 (J5Z97_01150) | - | 201611..201799 (+) | 189 | WP_032460866.1 | hypothetical protein | - |
| J5Z97_RS01155 (J5Z97_01155) | dnaB | 201771..203126 (+) | 1356 | WP_194118452.1 | replicative DNA helicase | - |
| J5Z97_RS01160 (J5Z97_01160) | - | 203119..203928 (+) | 810 | WP_115222977.1 | conserved phage C-terminal domain-containing protein | - |
| J5Z97_RS01165 (J5Z97_01165) | - | 203929..204750 (+) | 822 | WP_115222975.1 | ATP-binding protein | - |
| J5Z97_RS01170 (J5Z97_01170) | - | 204750..204977 (+) | 228 | WP_032460879.1 | hypothetical protein | - |
| J5Z97_RS01175 (J5Z97_01175) | - | 204967..205167 (+) | 201 | WP_181876623.1 | hypothetical protein | - |
| J5Z97_RS01180 (J5Z97_01180) | - | 205164..205370 (+) | 207 | WP_012678849.1 | hypothetical protein | - |
| J5Z97_RS01185 (J5Z97_01185) | - | 205381..205650 (+) | 270 | WP_115222973.1 | hypothetical protein | - |
| J5Z97_RS01190 (J5Z97_01190) | - | 205652..206008 (+) | 357 | WP_227877791.1 | HNH endonuclease signature motif containing protein | - |
| J5Z97_RS01195 (J5Z97_01195) | - | 206005..206148 (+) | 144 | WP_000564606.1 | hypothetical protein | - |
| J5Z97_RS01200 (J5Z97_01200) | - | 206145..206633 (+) | 489 | WP_050491258.1 | DUF1642 domain-containing protein | - |
| J5Z97_RS01205 (J5Z97_01205) | - | 206701..206922 (+) | 222 | WP_003057301.1 | hypothetical protein | - |
| J5Z97_RS01210 (J5Z97_01210) | ssbA | 206919..207311 (+) | 393 | WP_032460876.1 | single-stranded DNA-binding protein | Machinery gene |
| J5Z97_RS01215 (J5Z97_01215) | - | 207325..207603 (+) | 279 | WP_029713970.1 | hypothetical protein | - |
| J5Z97_RS01220 (J5Z97_01220) | - | 207698..207925 (+) | 228 | WP_136075349.1 | hypothetical protein | - |
| J5Z97_RS01225 (J5Z97_01225) | - | 207897..208361 (+) | 465 | WP_063629750.1 | hypothetical protein | - |
| J5Z97_RS01230 (J5Z97_01230) | - | 208471..209013 (+) | 543 | WP_063629749.1 | site-specific integrase | - |
| J5Z97_RS01235 (J5Z97_01235) | - | 209183..209365 (+) | 183 | WP_063629748.1 | hypothetical protein | - |
| J5Z97_RS09215 | - | 209754..209948 (+) | 195 | WP_227877792.1 | HNH endonuclease | - |
| J5Z97_RS01245 (J5Z97_01245) | - | 210066..210551 (+) | 486 | WP_136276233.1 | hypothetical protein | - |
| J5Z97_RS01250 (J5Z97_01250) | - | 210544..212256 (+) | 1713 | WP_111685857.1 | terminase TerL endonuclease subunit | - |
| J5Z97_RS01255 (J5Z97_01255) | - | 212265..213407 (+) | 1143 | WP_115222967.1 | phage portal protein | - |
| J5Z97_RS01260 (J5Z97_01260) | - | 213458..214000 (+) | 543 | WP_063629746.1 | HK97 family phage prohead protease | - |
| J5Z97_RS01265 (J5Z97_01265) | - | 214011..215273 (+) | 1263 | WP_115222965.1 | phage major capsid protein | - |
| J5Z97_RS01270 (J5Z97_01270) | - | 215293..215631 (+) | 339 | WP_032460894.1 | hypothetical protein | - |
| J5Z97_RS01275 (J5Z97_01275) | - | 215628..215933 (+) | 306 | WP_032460893.1 | head-tail adaptor protein | - |
| J5Z97_RS01280 (J5Z97_01280) | - | 215933..216280 (+) | 348 | WP_032460892.1 | hypothetical protein | - |
| J5Z97_RS01285 (J5Z97_01285) | - | 216267..216611 (+) | 345 | WP_136276235.1 | HK97 gp10 family phage protein | - |
| J5Z97_RS01290 (J5Z97_01290) | - | 216626..217297 (+) | 672 | WP_063629743.1 | phage tail protein | - |
| J5Z97_RS01295 (J5Z97_01295) | - | 217301..217774 (+) | 474 | WP_136276237.1 | hypothetical protein | - |
| J5Z97_RS01300 (J5Z97_01300) | - | 217964..220699 (+) | 2736 | WP_136276239.1 | phage tail tape measure protein | - |
| J5Z97_RS01305 (J5Z97_01305) | - | 220696..221418 (+) | 723 | WP_136026304.1 | phage tail protein | - |
| J5Z97_RS01310 (J5Z97_01310) | - | 221419..223362 (+) | 1944 | WP_227877794.1 | phage tail spike protein | - |
| J5Z97_RS01315 (J5Z97_01315) | hylP | 223359..224474 (+) | 1116 | WP_011528782.1 | hyaluronoglucosaminidase | - |
| J5Z97_RS01320 (J5Z97_01320) | - | 224489..226270 (+) | 1782 | WP_136075352.1 | gp58-like family protein | - |
| J5Z97_RS01325 (J5Z97_01325) | - | 226279..226707 (+) | 429 | WP_011528780.1 | DUF1617 family protein | - |
| J5Z97_RS01330 (J5Z97_01330) | - | 226710..227342 (+) | 633 | WP_136075353.1 | hypothetical protein | - |
| J5Z97_RS01335 (J5Z97_01335) | - | 227354..227626 (+) | 273 | WP_011017397.1 | hypothetical protein | - |
| J5Z97_RS01340 (J5Z97_01340) | - | 227623..227850 (+) | 228 | WP_003058873.1 | phage holin | - |
| J5Z97_RS01345 (J5Z97_01345) | - | 227966..229168 (+) | 1203 | WP_136075354.1 | glucosaminidase domain-containing protein | - |
| J5Z97_RS01350 (J5Z97_01350) | - | 229241..229444 (-) | 204 | WP_115223322.1 | helix-turn-helix transcriptional regulator | - |
| J5Z97_RS01355 (J5Z97_01355) | speG | 230093..230797 (+) | 705 | WP_023611016.1 | streptococcal pyrogenic exotoxin SpeG | - |
| J5Z97_RS01360 (J5Z97_01360) | - | 231254..232603 (+) | 1350 | WP_023611015.1 | glucose-6-phosphate isomerase | - |
| J5Z97_RS01365 (J5Z97_01365) | - | 232952..234460 (-) | 1509 | WP_002986134.1 | helix-turn-helix domain-containing protein | - |
| J5Z97_RS01370 (J5Z97_01370) | - | 235148..235819 (+) | 672 | WP_023611018.1 | rhomboid family intramembrane serine protease | - |
| J5Z97_RS01375 (J5Z97_01375) | galU | 235918..236817 (-) | 900 | WP_002986125.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| J5Z97_RS01380 (J5Z97_01380) | - | 236850..237866 (-) | 1017 | WP_011284483.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| J5Z97_RS01385 (J5Z97_01385) | - | 238033..239166 (-) | 1134 | WP_000564846.1 | ISAs1-like element IS1548 family transposase | - |
| J5Z97_RS01390 (J5Z97_01390) | - | 239490..239939 (+) | 450 | WP_002986120.1 | MarR family transcriptional regulator | - |
| J5Z97_RS01395 (J5Z97_01395) | - | 239932..241638 (+) | 1707 | WP_002991196.1 | ABC transporter ATP-binding protein | - |
| J5Z97_RS01400 (J5Z97_01400) | - | 241641..243425 (+) | 1785 | WP_002986115.1 | ABC transporter ATP-binding protein | - |
| J5Z97_RS01405 (J5Z97_01405) | - | 243543..244310 (+) | 768 | WP_011054158.1 | epoxyqueuosine reductase QueH | - |
| J5Z97_RS01410 (J5Z97_01410) | - | 244420..244866 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| J5Z97_RS01415 (J5Z97_01415) | radA | 244947..246308 (+) | 1362 | WP_002986109.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49386.68 Da Isoelectric Point: 6.0962
>NTDB_id=550461 J5Z97_RS01415 WP_002986109.1 244947..246308(+) (radA) [Streptococcus pyogenes strain M08500]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=550461 J5Z97_RS01415 WP_002986109.1 244947..246308(+) (radA) [Streptococcus pyogenes strain M08500]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACATATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTGCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATTTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACATATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTGCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATTGGCATTTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGCTTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.872 |
100 |
0.859 |
| radA | Streptococcus pneumoniae D39 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae R6 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae Rx1 |
85.651 |
100 |
0.857 |
| radA | Streptococcus mitis SK321 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae TIGR4 |
85.651 |
100 |
0.857 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |