Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   J4Z27_RS06145 Genome accession   NZ_CP071992
Coordinates   1294976..1295950 (+) Length   324 a.a.
NCBI ID   WP_002446534.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain CBPA-ST-11003     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1289976..1300950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4Z27_RS06110 (J4Z27_001219) rpmG 1290458..1290607 (+) 150 WP_001830957.1 50S ribosomal protein L33 -
  J4Z27_RS06115 (J4Z27_001220) - 1290788..1291339 (+) 552 WP_002446539.1 5-formyltetrahydrofolate cyclo-ligase -
  J4Z27_RS06120 (J4Z27_001221) - 1291340..1292800 (+) 1461 WP_002446538.1 rhomboid family protein -
  J4Z27_RS06125 (J4Z27_001222) - 1292784..1292984 (+) 201 WP_002446537.1 YqgQ family protein -
  J4Z27_RS06130 (J4Z27_001223) - 1292984..1293970 (+) 987 WP_002446536.1 ROK family glucokinase -
  J4Z27_RS06135 (J4Z27_001224) - 1293970..1294296 (+) 327 WP_001831234.1 MTH1187 family thiamine-binding protein -
  J4Z27_RS06140 (J4Z27_001225) - 1294296..1294919 (+) 624 WP_002446535.1 MBL fold metallo-hydrolase -
  J4Z27_RS06145 (J4Z27_001226) comGA 1294976..1295950 (+) 975 WP_002446534.1 competence type IV pilus ATPase ComGA Machinery gene
  J4Z27_RS06150 (J4Z27_001227) comGB 1295922..1296989 (+) 1068 WP_002446533.1 competence type IV pilus assembly protein ComGB Machinery gene
  J4Z27_RS06155 (J4Z27_001228) comGC 1297007..1297324 (+) 318 WP_002446532.1 competence type IV pilus major pilin ComGC Machinery gene
  J4Z27_RS06160 (J4Z27_001229) comGD 1297314..1297751 (+) 438 WP_002446531.1 competence type IV pilus minor pilin ComGD -
  J4Z27_RS06165 (J4Z27_001230) - 1297738..1298031 (+) 294 WP_002446530.1 hypothetical protein -
  J4Z27_RS06170 (J4Z27_001231) comGF 1297955..1298446 (+) 492 WP_002446529.1 competence type IV pilus minor pilin ComGF -
  J4Z27_RS06175 (J4Z27_001232) - 1298611..1299123 (+) 513 WP_002446528.1 shikimate kinase -
  J4Z27_RS06180 (J4Z27_001233) gcvT 1299341..1300432 (+) 1092 WP_002446527.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 37261.33 Da        Isoelectric Point: 8.8257

>NTDB_id=549820 J4Z27_RS06145 WP_002446534.1 1294976..1295950(+) (comGA) [Staphylococcus epidermidis strain CBPA-ST-11003]
MKILFEQIINHAIKQEASDIHFIPCEEHTIIKLRIKDELTIYDTLSFPIYKKLLIYMKFQSGLDVSTQHRAQSGRYSYKM
KRLYYLRISTLPLSLGNESCVIRIVPQYFQTKRESYEFKDFKHFMKKKQGLLLFSGPTGSGKSTLMYQMVLYAHQNLNLN
VISVEDPVEQILNGITQISVNEKAGINYESSFKAILRCDPDVILIGEIRDSTVAKYVIQASLSGHLVLSTMHANDCKGAL
LRLLEMGISVQELCQAINLISNQRLITTTTNTRQLVSELMFQSQINYFFEHNHSLPKNFTKLSTHLNKMSKEGVICEEVV
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=549820 J4Z27_RS06145 WP_002446534.1 1294976..1295950(+) (comGA) [Staphylococcus epidermidis strain CBPA-ST-11003]
TTGAAAATTTTATTTGAACAGATTATCAATCATGCAATTAAGCAAGAAGCAAGTGACATACACTTTATACCATGTGAGGA
ACACACTATAATTAAGCTAAGAATTAAAGATGAGCTCACAATATATGATACACTTTCATTTCCAATTTATAAAAAATTAC
TTATATACATGAAGTTTCAATCTGGGTTAGATGTATCAACACAGCATAGGGCACAAAGTGGTAGATATAGTTATAAGATG
AAGCGTTTATATTATTTAAGAATCTCTACATTACCGTTATCATTAGGCAATGAAAGTTGTGTAATTCGTATAGTACCTCA
ATACTTCCAAACTAAACGAGAATCATATGAATTTAAAGATTTTAAACATTTCATGAAAAAGAAACAAGGTCTACTTTTGT
TTAGTGGGCCAACTGGCTCTGGCAAAAGTACTTTAATGTACCAAATGGTCCTTTATGCACATCAAAATTTGAATTTAAAT
GTAATATCAGTTGAAGATCCAGTAGAACAAATACTCAATGGAATCACACAAATATCAGTTAATGAAAAGGCAGGTATAAA
TTATGAAAGCTCTTTCAAAGCCATTTTAAGGTGTGATCCGGACGTAATTTTAATTGGTGAAATCAGAGATTCTACCGTAG
CTAAATACGTGATTCAAGCCAGTTTAAGTGGACATTTAGTTTTGTCGACAATGCACGCGAATGATTGCAAGGGAGCATTA
TTACGATTATTAGAAATGGGTATTTCTGTCCAAGAGTTGTGCCAGGCAATCAATTTAATTTCTAATCAAAGATTAATCAC
TACTACTACAAATACTCGTCAACTAGTATCGGAATTAATGTTTCAAAGCCAAATCAATTATTTTTTTGAACATAATCATT
CTTTACCTAAAAATTTCACAAAATTATCTACACATTTAAACAAAATGTCTAAAGAAGGTGTTATATGTGAAGAAGTTGTC
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

70.062

100

0.701
  comGA Staphylococcus aureus N315

70.062

100

0.701