Detailed information NTG0549811

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: J4Z27_RS04530
• Genome accession: NZ_CP071992
• Coordinates: 975671..976717 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain CBPA-ST-11003
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 970671..981717

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4Z27_RS04505 (J4Z27_000897)	isaB	971811..972347 (+)	537	WP_002447446.1	immunodominant staphylococcal antigen IsaB family protein	-
J4Z27_RS04510 (J4Z27_000898)	-	972499..973485 (-)	987	WP_002447445.1	FUSC family protein	-
J4Z27_RS04515 (J4Z27_000899)	map	973659..974414 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
J4Z27_RS04520 (J4Z27_000900)	-	974572..974958 (+)	387	WP_002495657.1	hypothetical protein	-
J4Z27_RS04525 (J4Z27_000901)	liaF	974973..975674 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
J4Z27_RS04530 (J4Z27_000902)	vraS	975671..976717 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
J4Z27_RS04535 (J4Z27_000903)	vraR	976707..977336 (+)	630	WP_002447440.1	two-component system response regulator VraR	Regulator
J4Z27_RS04540 (J4Z27_000904)	-	977393..978571 (-)	1179	WP_002447439.1	YihY/virulence factor BrkB family protein	-
J4Z27_RS04545 (J4Z27_000905)	-	978977..979261 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
J4Z27_RS04550 (J4Z27_000906)	-	979269..979733 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
J4Z27_RS04555 (J4Z27_000907)	-	979875..980090 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
J4Z27_RS04560 (J4Z27_000908)	-	980092..981333 (+)	1242	WP_002447437.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=549811 J4Z27_RS04530 WP_002447441.1 975671..976717(+) (vraS) [Staphylococcus epidermidis strain CBPA-ST-11003]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=549811 J4Z27_RS04530 WP_002447441.1 975671..976717(+) (vraS) [Staphylococcus epidermidis strain CBPA-ST-11003]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATAGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTGGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAGCGACTTGCTAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACAAGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914