Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   J4Z26_RS01310 Genome accession   NZ_CP071988
Coordinates   310852..311526 (+) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain CBPA-ST-10002 isolate HPB10235     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 300825..320052 310852..311526 within 0


Gene organization within MGE regions


Location: 300825..320052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4Z26_RS01255 (J4Z26_000252) tnpA 300825..301307 (+) 483 WP_001832528.1 IS200/IS605-like element ISSep3 family transposase -
  J4Z26_RS01260 (J4Z26_000253) - 301445..301968 (+) 524 Protein_250 DNA/RNA non-specific endonuclease -
  J4Z26_RS01265 - 301997..302342 (-) 346 Protein_251 recombinase family protein -
  J4Z26_RS01270 (J4Z26_000255) - 302824..303723 (-) 900 WP_000196697.1 Mph(C) family macrolide 2'-phosphotransferase -
  J4Z26_RS01275 (J4Z26_000256) msr(A) 303822..305288 (-) 1467 WP_000438873.1 ABC-F type ribosomal protection protein Msr(A) -
  J4Z26_RS01280 (J4Z26_000257) - 305762..306436 (+) 675 WP_001105960.1 IS6 family transposase -
  J4Z26_RS01285 (J4Z26_000258) - 306522..306695 (-) 174 WP_000044738.1 hypothetical protein -
  J4Z26_RS01290 (J4Z26_000259) - 306739..307359 (-) 621 WP_000941203.1 LysE/ArgO family amino acid transporter -
  J4Z26_RS01295 (J4Z26_000260) - 307364..308335 (-) 972 WP_000053810.1 fatty acid desaturase family protein -
  J4Z26_RS01300 (J4Z26_000261) - 308434..309846 (+) 1413 WP_000526300.1 PLP-dependent aminotransferase family protein -
  J4Z26_RS01305 (J4Z26_000262) - 310038..310712 (+) 675 WP_001105960.1 IS6 family transposase -
  J4Z26_RS01310 (J4Z26_000263) braR 310852..311526 (+) 675 WP_000866106.1 response regulator transcription factor Regulator
  J4Z26_RS01315 (J4Z26_000264) - 311523..312404 (+) 882 Protein_261 sensor histidine kinase -
  J4Z26_RS01320 (J4Z26_000265) - 312520..313449 (+) 930 WP_000793446.1 ABC transporter ATP-binding protein -
  J4Z26_RS01325 (J4Z26_000266) - 313442..314179 (+) 738 WP_000369394.1 ABC transporter permease -
  J4Z26_RS01330 (J4Z26_000267) - 314193..314381 (+) 189 Protein_264 undecaprenyl-diphosphate phosphatase -
  J4Z26_RS01335 (J4Z26_000268) - 314426..315100 (+) 675 WP_001105960.1 IS6 family transposase -
  J4Z26_RS01340 (J4Z26_000269) - 315241..315876 (+) 636 Protein_266 aminoglycoside 6-adenylyltransferase -
  J4Z26_RS01345 (J4Z26_000270) sat4 315873..316415 (+) 543 WP_000627290.1 streptothricin N-acetyltransferase Sat4 -
  J4Z26_RS01350 (J4Z26_000271) aph(3')-IIIa 316508..317302 (+) 795 WP_001096887.1 aminoglycoside O-phosphotransferase APH(3')-IIIa -
  J4Z26_RS01355 - 317578..317709 (+) 132 Protein_269 HTH domain-containing protein -
  J4Z26_RS01360 - 317785..318530 (+) 746 Protein_270 helix-turn-helix transcriptional regulator -
  J4Z26_RS01365 (J4Z26_000274) - 318641..319300 (+) 660 WP_000802831.1 dihydrofolate reductase family protein -
  J4Z26_RS01370 (J4Z26_000275) - 319378..320052 (-) 675 WP_001105960.1 IS6 family transposase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=549767 J4Z26_RS01310 WP_000866106.1 310852..311526(+) (braR) [Staphylococcus epidermidis strain CBPA-ST-10002 isolate HPB10235]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=549767 J4Z26_RS01310 WP_000866106.1 310852..311526(+) (braR) [Staphylococcus epidermidis strain CBPA-ST-10002 isolate HPB10235]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656