Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J5D23_RS03905 Genome accession   NZ_CP071987
Coordinates   836633..838417 (+) Length   594 a.a.
NCBI ID   WP_209613494.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5136     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 831633..843417
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D23_RS03875 (J5D23_03875) motB 832398..833171 (+) 774 WP_001085296.1 flagellar motor protein MotB -
  J5D23_RS03880 (J5D23_03880) - 833177..833614 (+) 438 WP_001039460.1 hypothetical protein -
  J5D23_RS03885 (J5D23_03885) - 833683..835344 (+) 1662 WP_077366888.1 ABC transporter permease/substrate-binding protein -
  J5D23_RS03890 (J5D23_03890) - 835347..835997 (+) 651 WP_077366890.1 ATP-binding cassette domain-containing protein -
  J5D23_RS03895 (J5D23_03895) - 836000..836179 (-) 180 WP_000468798.1 hypothetical protein -
  J5D23_RS03900 (J5D23_03900) - 836171..836632 (+) 462 WP_000437159.1 hypothetical protein -
  J5D23_RS03905 (J5D23_03905) uvrC 836633..838417 (+) 1785 WP_209613494.1 excinuclease ABC subunit UvrC Machinery gene
  J5D23_RS03910 (J5D23_03910) - 838428..839693 (+) 1266 WP_209613496.1 homoserine dehydrogenase -
  J5D23_RS03915 (J5D23_03915) - 839694..840038 (+) 345 WP_001211711.1 YraN family protein -
  J5D23_RS03920 (J5D23_03920) trxA 840127..840447 (+) 321 WP_000020206.1 thioredoxin -
  J5D23_RS03925 (J5D23_03925) trxB 840453..841388 (+) 936 WP_077366896.1 thioredoxin-disulfide reductase -
  J5D23_RS03930 (J5D23_03930) - 841978..842799 (+) 822 WP_077366898.1 glycosyltransferase family 25 protein -
  J5D23_RS03935 (J5D23_03935) - 843018..843266 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68690.94 Da        Isoelectric Point: 9.7560

>NTDB_id=549757 J5D23_RS03905 WP_209613494.1 836633..838417(+) (uvrC) [Helicobacter pylori strain MT5136]
MADLLSGLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRASLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSIDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMLYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
TCSSETLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTISHTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=549757 J5D23_RS03905 WP_209613494.1 836633..838417(+) (uvrC) [Helicobacter pylori strain MT5136]
ATGGCTGATTTATTATCCGGTTTGAAAAACCTTTCTAGCAGTAGTGGGGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCAAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCCA
ACCCTCGCGCAAGCTTACGCGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCTATTGATTTCCCTATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGTGGGGCTAAGGACATTTTGGACAGCTTGTATGAATTGCTCCCTTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGCTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGAGATAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGTGGGAACAATAAGGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTCAATGGGTTTGACA
CTGATGAAGCGATGAAGCAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAGC
ACTTGCTCTAGTGAAACACTTAAAGAATTGCAAGAATTTATCTCTCACCAATATTCTAAAAAAATCGCTCTTAATATCCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTTAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAATAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAACGCCTTTCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATTGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGATTAGTCATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

95.616

99.832

0.955