Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   J5D23_RS00100 Genome accession   NZ_CP071987
Coordinates   14947..17310 (+) Length   787 a.a.
NCBI ID   WP_209613991.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5136     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9947..22310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D23_RS00075 (J5D23_00075) dnaG 10343..12022 (+) 1680 WP_209613988.1 DNA primase -
  J5D23_RS00080 (J5D23_00080) - 12019..13071 (+) 1053 WP_209613989.1 MnmA/TRMU family protein -
  J5D23_RS00085 (J5D23_00085) - 13429..14256 (+) 828 WP_209613990.1 DUF5718 family protein -
  J5D23_RS00090 (J5D23_00090) comB2 14401..14682 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  J5D23_RS00095 (J5D23_00095) comB3 14682..14945 (+) 264 WP_187892425.1 competence protein ComB Machinery gene
  J5D23_RS00100 (J5D23_00100) comB4 14947..17310 (+) 2364 WP_209613991.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  J5D23_RS00110 (J5D23_00110) - 17567..18955 (+) 1389 WP_165561955.1 COG3014 family protein -
  J5D23_RS00115 (J5D23_00115) cheV1 19062..20027 (+) 966 WP_000785452.1 chemotaxis protein CheV1 -
  J5D23_RS00120 (J5D23_00120) nspC 20024..21241 (+) 1218 WP_000760818.1 carboxynorspermidine decarboxylase -
  J5D23_RS00125 (J5D23_00125) lpxE 21292..21825 (-) 534 WP_228921301.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90225.65 Da        Isoelectric Point: 8.2569

>NTDB_id=549745 J5D23_RS00100 WP_209613991.1 14947..17310(+) (comB4) [Helicobacter pylori strain MT5136]
MLEKFLGAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYKQSIQSDSKYLQAILNQFENKEVYENQYFLVLESTHSLQGVLEHKKKSFMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSAHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIYLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISSAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSSAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=549745 J5D23_RS00100 WP_209613991.1 14947..17310(+) (comB4) [Helicobacter pylori strain MT5136]
ATGTTAGAAAAGTTTTTAGGCGCTATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCAAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGTCAGATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTGGTGGTTAAAAGGCGTAAAATTGATTATAAACAAAGCATTCAATCTGATTCTAA
ATACTTGCAAGCGATCTTGAACCAGTTTGAAAACAAAGAAGTGTATGAAAATCAGTATTTTTTGGTTTTAGAAAGCACTC
ACTCTTTGCAGGGCGTTTTAGAGCATAAGAAAAAATCTTTCATGCACGCTAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGTTC
TAAAGAGGTTTTGAATTTTTATGCAGAATATATTAATGGGTTTGATCTCCCCCTAAAGCCCTTAGTAGGGGGGTATTTGA
GCGACAGCTATATCGCTAGTTCCATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGTTTTAACCAAAAAACCTATAAC
CGCTTGATTGGTATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACGCC
TTTGGATATTATCTTTTCCATAGAGCCTATGAGCGCACATAAAACGCTGAGTTTTTTAAAAGAGAGGGCCAAGTTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGTTAGAATACCAGGAATTAGTCAAAACCAAACGATTATCCATGCAAAAATTCGCC
CTAAACATCCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATTTATTTAAACC
ACCGCTTGCGTTTTTTGACCTCTAAAGCCCTAGCGTGTTTGATGGTGTTTGAAAGGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCATAATAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATATCAGAACATGCGCCTTTTGGCCTTTGACAGGATGCAAGGGCTG
TATTCTTTCACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAACCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTTGATCTCGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTAGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGATTTTAGTTTGCTGGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAGTGCTTTTTTAAACGTGATCAACCTAGACGCTATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAGATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGATATTTACCAACTCAGCGGGGTCAAAAACGCCCACAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAATTGAAACACAACTTCAATGTGCCTTTGAGCGAGACTGAAATTTCA
TTTTTAGAAAACACGCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGCTCTAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAGATCTTTAATTCGGATTCTAGTCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.205

100

0.972