Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J5D26_RS03925 Genome accession   NZ_CP071985
Coordinates   839906..841690 (+) Length   594 a.a.
NCBI ID   WP_209508390.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5119     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 834906..846690
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D26_RS03895 (J5D26_03895) motB 835625..836398 (+) 774 WP_001085367.1 flagellar motor protein MotB -
  J5D26_RS03900 (J5D26_03900) - 836404..836841 (+) 438 WP_000802458.1 hypothetical protein -
  J5D26_RS03905 (J5D26_03905) - 836955..838616 (+) 1662 WP_209508385.1 ABC transporter permease/substrate-binding protein -
  J5D26_RS03910 (J5D26_03910) - 838619..839269 (+) 651 WP_209508387.1 ATP-binding cassette domain-containing protein -
  J5D26_RS03915 (J5D26_03915) - 839273..839452 (-) 180 WP_209508389.1 hypothetical protein -
  J5D26_RS03920 (J5D26_03920) - 839444..839905 (+) 462 WP_000437164.1 hypothetical protein -
  J5D26_RS03925 (J5D26_03925) uvrC 839906..841690 (+) 1785 WP_209508390.1 excinuclease ABC subunit UvrC Machinery gene
  J5D26_RS03930 (J5D26_03930) - 841701..842966 (+) 1266 WP_187945794.1 homoserine dehydrogenase -
  J5D26_RS03935 (J5D26_03935) - 842967..843311 (+) 345 WP_001211718.1 YraN family protein -
  J5D26_RS03940 (J5D26_03940) trxA 843400..843720 (+) 321 WP_000020189.1 thioredoxin -
  J5D26_RS03945 (J5D26_03945) trxB 843726..844661 (+) 936 WP_209508391.1 thioredoxin-disulfide reductase -
  J5D26_RS03950 (J5D26_03950) - 845020..845841 (+) 822 WP_209508392.1 glycosyltransferase family 25 protein -
  J5D26_RS03955 (J5D26_03955) - 846060..846308 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68718.00 Da        Isoelectric Point: 9.7496

>NTDB_id=549719 J5D26_RS03925 WP_209508390.1 839906..841690(+) (uvrC) [Helicobacter pylori strain MT5119]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRVSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSIDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEVLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSSEDRILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRTQLNIALEILKSSGS
FVEVIAISKEKKDSKAYRSKGGAKDIIHTISNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKSI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=549719 J5D26_RS03925 WP_209508390.1 839906..841690(+) (uvrC) [Helicobacter pylori strain MT5119]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGAGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCAAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCTA
ATCCTCGCGTAAGCTTACGCATTCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCAAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCTATTGATTTCCCTATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCTTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAATATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTGATTTATAGGGATAGGATTGCTAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGTGGGAACAATAAAGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAGGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAGC
GCTTGCTCTAATGAGGTGCTTAAAGAATTGCAGGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAATATCCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
GTGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTCAATTTAGAGTGCGTGCCTTATAGGGTAGAAATCTTTGACACA
AGCCATCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCCTTTCAAAAAAACTCTTATCGGCG
TTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGACGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAAGGATTCTAAGGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGATTAGTAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGAGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

95.447

99.832

0.953