Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J5D20_RS03915 Genome accession   NZ_CP071984
Coordinates   839683..841467 (+) Length   594 a.a.
NCBI ID   WP_209525276.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5114     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 834683..846467
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D20_RS03885 (J5D20_03885) motB 835403..836176 (+) 774 WP_209525272.1 flagellar motor protein MotB -
  J5D20_RS03890 (J5D20_03890) - 836182..836619 (+) 438 WP_000802458.1 hypothetical protein -
  J5D20_RS03895 (J5D20_03895) - 836733..838394 (+) 1662 WP_209528363.1 glycine betaine ABC transporter substrate-binding protein -
  J5D20_RS03900 (J5D20_03900) - 838397..839047 (+) 651 WP_097707144.1 ATP-binding cassette domain-containing protein -
  J5D20_RS03905 (J5D20_03905) - 839050..839229 (-) 180 WP_000468793.1 hypothetical protein -
  J5D20_RS03910 (J5D20_03910) - 839221..839682 (+) 462 WP_000437159.1 hypothetical protein -
  J5D20_RS03915 (J5D20_03915) uvrC 839683..841467 (+) 1785 WP_209525276.1 excinuclease ABC subunit UvrC Machinery gene
  J5D20_RS03920 (J5D20_03920) - 841478..842743 (+) 1266 WP_097707141.1 homoserine dehydrogenase -
  J5D20_RS03925 (J5D20_03925) - 842744..843088 (+) 345 WP_001211704.1 YraN family protein -
  J5D20_RS03930 (J5D20_03930) trxA 843180..843500 (+) 321 WP_000020206.1 thioredoxin -
  J5D20_RS03935 (J5D20_03935) trxB 843506..844441 (+) 936 WP_000564382.1 thioredoxin-disulfide reductase -
  J5D20_RS03940 (J5D20_03940) - 844809..845630 (+) 822 WP_097707140.1 glycosyltransferase family 25 protein -
  J5D20_RS03945 (J5D20_03945) - 845849..846097 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68700.89 Da        Isoelectric Point: 9.7560

>NTDB_id=549697 J5D20_RS03915 WP_209525276.1 839683..841467(+) (uvrC) [Helicobacter pylori strain MT5114]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNPRASLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSIDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEVLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEVRSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTTSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=549697 J5D20_RS03915 WP_209525276.1 839683..841467(+) (uvrC) [Helicobacter pylori strain MT5114]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGGGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCCTCGCGCAAGCTTACGCGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCTATTGATTTCCCTATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGTGGGGCTAAGGACATTTTGGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGATAGGATTGCTAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATCTGGATATTTTTGCTTTTTATGGTGGGAACAATAAAGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAGC
GCTTGCTCTAATGAGGTGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAATATCCC
TAAAAAGGGTGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGTGCGATCGCTCTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCCTTTCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATTGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCCATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGACTAGTAATACTTTTAAATTACTCCCTAGCGACAAACGCTTACAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

95.953

99.832

0.958