Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J5D21_RS03920 Genome accession   NZ_CP071982
Coordinates   838970..840754 (+) Length   594 a.a.
NCBI ID   WP_209611185.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5135     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 833970..845754
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D21_RS03890 (J5D21_03890) motB 834689..835462 (+) 774 WP_001085354.1 flagellar motor protein MotB -
  J5D21_RS03895 (J5D21_03895) - 835459..835905 (+) 447 WP_001081239.1 hypothetical protein -
  J5D21_RS03900 (J5D21_03900) - 836019..837680 (+) 1662 WP_209611183.1 glycine betaine ABC transporter substrate-binding protein -
  J5D21_RS03905 (J5D21_03905) - 837683..838333 (+) 651 WP_000659409.1 ATP-binding cassette domain-containing protein -
  J5D21_RS03910 (J5D21_03910) - 838337..838516 (-) 180 WP_000468794.1 hypothetical protein -
  J5D21_RS03915 (J5D21_03915) - 838508..838969 (+) 462 WP_000437154.1 hypothetical protein -
  J5D21_RS03920 (J5D21_03920) uvrC 838970..840754 (+) 1785 WP_209611185.1 excinuclease ABC subunit UvrC Machinery gene
  J5D21_RS03925 (J5D21_03925) - 840765..842030 (+) 1266 WP_000746757.1 homoserine dehydrogenase -
  J5D21_RS03930 (J5D21_03930) - 842031..842375 (+) 345 WP_001211704.1 YraN family protein -
  J5D21_RS03935 (J5D21_03935) trxA 842464..842784 (+) 321 WP_000020206.1 thioredoxin -
  J5D21_RS03940 (J5D21_03940) trxB 842790..843725 (+) 936 WP_209611187.1 thioredoxin-disulfide reductase -
  J5D21_RS03945 (J5D21_03945) - 844093..844914 (+) 822 WP_001263392.1 glycosyltransferase family 25 protein -
  J5D21_RS03950 (J5D21_03950) - 845133..845381 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68612.78 Da        Isoelectric Point: 9.7128

>NTDB_id=549677 J5D21_RS03920 WP_209611185.1 838970..840754(+) (uvrC) [Helicobacter pylori strain MT5135]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNPRASLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSIDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTISNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASDQEKNAVLKKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=549677 J5D21_RS03920 WP_209611185.1 838970..840754(+) (uvrC) [Helicobacter pylori strain MT5135]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGGGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCATAACAATGAAATCACGCCCA
ATCCTCGCGCAAGCTTACGCGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCTATTGATTTCCCTATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATTAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTCATTTACAGGGATAGGATAGCTAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGTGGGAACAACAAGGCGGT
GTTAGTGAAAATGTTCATGCGTGGAGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAAGCGATGAAGCAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAGC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAGGGTGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTCAATTTAGAGTGCGTGCCTTATAGGGTAGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTTCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACTAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGATTAGTAATACTTTTAAATTACTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGATCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAAAATAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.459

99.832

0.963