Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J5D24_RS04050 Genome accession   NZ_CP071978
Coordinates   860543..862327 (+) Length   594 a.a.
NCBI ID   WP_097707142.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5125     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 855543..867327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D24_RS04020 (J5D24_04020) motB 856262..857035 (+) 774 WP_001085355.1 flagellar motor protein MotB -
  J5D24_RS04025 (J5D24_04025) - 857041..857478 (+) 438 WP_000802458.1 hypothetical protein -
  J5D24_RS04030 (J5D24_04030) - 857593..859254 (+) 1662 WP_209507612.1 glycine betaine ABC transporter substrate-binding protein -
  J5D24_RS04035 (J5D24_04035) - 859257..859907 (+) 651 WP_097707144.1 ATP-binding cassette domain-containing protein -
  J5D24_RS04040 (J5D24_04040) - 859910..860089 (-) 180 WP_000468793.1 hypothetical protein -
  J5D24_RS04045 (J5D24_04045) - 860081..860542 (+) 462 WP_097707143.1 hypothetical protein -
  J5D24_RS04050 (J5D24_04050) uvrC 860543..862327 (+) 1785 WP_097707142.1 excinuclease ABC subunit UvrC Machinery gene
  J5D24_RS04055 (J5D24_04055) - 862338..863603 (+) 1266 WP_097707141.1 homoserine dehydrogenase -
  J5D24_RS04060 (J5D24_04060) - 863604..863948 (+) 345 WP_001211704.1 YraN family protein -
  J5D24_RS04065 (J5D24_04065) trxA 864040..864360 (+) 321 WP_000020199.1 thioredoxin -
  J5D24_RS04070 (J5D24_04070) trxB 864366..865301 (+) 936 WP_097707162.1 thioredoxin-disulfide reductase -
  J5D24_RS04075 (J5D24_04075) - 865671..866492 (+) 822 WP_097707140.1 glycosyltransferase family 25 protein -
  J5D24_RS04080 (J5D24_04080) - 866717..866965 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68688.83 Da        Isoelectric Point: 9.7560

>NTDB_id=549632 J5D24_RS04050 WP_097707142.1 860543..862327(+) (uvrC) [Helicobacter pylori strain MT5125]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNPRASLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSIDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSINGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSNEERILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTTSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=549632 J5D24_RS04050 WP_097707142.1 860543..862327(+) (uvrC) [Helicobacter pylori strain MT5125]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGGGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ATCCTCGCGCAAGCTTACGCGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCTATTGATTTCCCTATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGTGGGGCTAAGGACATTTTGGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGATAGGATTGCTAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATCTGGATATTTTTGCTTTTTATGGCGGGAACAATAAGGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCATCAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAGC
GCTTGTTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATTTCTCATCAATATTCTAAAAAAATCGCTCTTAATATCCC
TAAAAAGGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGAGCGGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCCTTTCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATTGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCCATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGACTAGTAATACTTTTAAATTACTCCCTAGCGACAAACGCTTACAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

95.953

99.832

0.958