Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   J5D24_RS00100 Genome accession   NZ_CP071978
Coordinates   14651..17014 (+) Length   787 a.a.
NCBI ID   WP_097708222.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5125     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 9651..22014
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D24_RS00070 (J5D24_00070) groES 9672..10028 (-) 357 WP_000671922.1 co-chaperone GroES -
  J5D24_RS00075 (J5D24_00075) dnaG 10314..11993 (+) 1680 WP_209507909.1 DNA primase -
  J5D24_RS00080 (J5D24_00080) - 11990..13042 (+) 1053 WP_097708224.1 MnmA/TRMU family protein -
  J5D24_RS00085 (J5D24_00085) - 13132..13959 (+) 828 WP_097708223.1 DUF5718 family protein -
  J5D24_RS00090 (J5D24_00090) comB2 14105..14386 (+) 282 WP_001272686.1 TrbC/VirB2 family protein Machinery gene
  J5D24_RS00095 (J5D24_00095) comB3 14386..14649 (+) 264 WP_000584948.1 hypothetical protein Machinery gene
  J5D24_RS00100 (J5D24_00100) comB4 14651..17014 (+) 2364 WP_097708222.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  J5D24_RS00110 (J5D24_00110) - 17319..18659 (+) 1341 WP_198994763.1 COG3014 family protein -
  J5D24_RS00115 (J5D24_00115) cheV1 18765..19730 (+) 966 WP_000785482.1 chemotaxis protein CheV1 -
  J5D24_RS00120 (J5D24_00120) nspC 19727..20944 (+) 1218 WP_209507911.1 carboxynorspermidine decarboxylase -
  J5D24_RS00125 (J5D24_00125) lpxE 20955..21515 (-) 561 WP_241894647.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90274.68 Da        Isoelectric Point: 8.2616

>NTDB_id=549621 J5D24_RS00100 WP_097708222.1 14651..17014(+) (comB4) [Helicobacter pylori strain MT5125]
MLEKFLGAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYKQSIQSDSKYLQAILNQFENKEVYENQYFLVLESAHSLHGVLEHKKKSFMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAIGALLYQETPLDIIFSIEPMSVNKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDTQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISYLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAISGAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSNAFFNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=549621 J5D24_RS00100 WP_097708222.1 14651..17014(+) (comB4) [Helicobacter pylori strain MT5125]
ATGTTAGAAAAGTTTTTAGGCGCTATCAAGCAAAAAGTTTCAAATTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGTGAAGAAAACAATATTTTAGGCTTGTATGATGAGCATTTTTTGCTCACTAAAAACGAAAACTTAGTGGGCATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCTTTGGAT
TCTTTGGAAAAAGTCGTGGCGCGCCTGGTGGTTAAAAGGCGTAAAATTGATTATAAACAAAGCATTCAATCTGACTCTAA
ATACTTGCAAGCGATCTTGAATCAGTTTGAAAATAAAGAAGTGTATGAGAATCAGTATTTTTTGGTTTTAGAAAGCGCGC
ACTCTTTGCATGGCGTTTTGGAGCATAAGAAAAAATCTTTCATGCACGCTAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAACTCAAAAATTATGCCCCCAAACTCTTAAGTTC
TAAAGAGGTTTTGAATTTTTATGCAGAATATATTAACGGGTTTGATCTCCCCTTAAAACCCCTAGTAGGAGGGTATTTGA
GCGACAGCTATATCGCTAGTTCCATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGTTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGATCGGAGCGCTTTTATACCAAGAGACTCC
ACTAGATATTATCTTTTCCATAGAGCCTATGAGCGTCAATAAAACGCTGAGTTTTTTAAAAGAGAGGGCCAAGTTTAGCA
TGTCTAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTGGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACACTCAAACGAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTGATGGTGTTTGAAAGGCAAAATTTAGGTTTTAAAGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAATAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTTTAGTTATAGGGGCAACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTATTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGACAGGATGCAAGGGCTG
TATTCTTTTACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAACCCCTTTTGTTTAGAGCCTAA
TTTGCAGAATTTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTTGATCTCGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTGGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGATTTTAGTTTGCTGGATTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGCTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTTAACGTGATAAACTTAGACGCGATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAGATCTTAGAAGAGTCTAGGAAAAACGACAGCGGCTTTTTGGTTTTTTTAGAC
GAATTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAACTCAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTTATTTTGTACCCGCAAAAAAACGCTAGGGAGTTGAAACACAACTTCAATGTGCCTTTGAGCGAGACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAAGTTTTAGTCAAAAATCTGGGTAATGGGAGCTCTAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAGATCTTTAATTCAGATTCTAGTCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.078

100

0.971