Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J5D22_RS03970 Genome accession   NZ_CP071977
Coordinates   846228..848012 (+) Length   594 a.a.
NCBI ID   WP_209505250.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5105     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 841228..853012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5D22_RS03940 (J5D22_03940) motB 841947..842720 (+) 774 WP_209505242.1 flagellar motor protein MotB -
  J5D22_RS03945 (J5D22_03945) - 842726..843163 (+) 438 WP_001039460.1 hypothetical protein -
  J5D22_RS03950 (J5D22_03950) - 843278..844939 (+) 1662 WP_077645656.1 ABC transporter permease/substrate-binding protein -
  J5D22_RS03955 (J5D22_03955) - 844942..845592 (+) 651 WP_001960676.1 ABC transporter ATP-binding protein -
  J5D22_RS03960 (J5D22_03960) - 845595..845774 (-) 180 WP_000468791.1 hypothetical protein -
  J5D22_RS03965 (J5D22_03965) - 845766..846227 (+) 462 WP_000437157.1 hypothetical protein -
  J5D22_RS03970 (J5D22_03970) uvrC 846228..848012 (+) 1785 WP_209505250.1 excinuclease ABC subunit UvrC Machinery gene
  J5D22_RS03975 (J5D22_03975) - 848023..849288 (+) 1266 WP_209505252.1 homoserine dehydrogenase -
  J5D22_RS03980 (J5D22_03980) - 849289..849633 (+) 345 WP_001211704.1 YraN family protein -
  J5D22_RS03985 (J5D22_03985) trxA 849722..850042 (+) 321 WP_021187058.1 thioredoxin -
  J5D22_RS03990 (J5D22_03990) trxB 850048..850983 (+) 936 WP_209505254.1 thioredoxin-disulfide reductase -
  J5D22_RS03995 (J5D22_03995) - 851351..852172 (+) 822 WP_209505256.1 glycosyltransferase family 25 protein -
  J5D22_RS04000 (J5D22_04000) - 852392..852640 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68835.04 Da        Isoelectric Point: 9.7157

>NTDB_id=549611 J5D22_RS03970 WP_209505250.1 846228..848012(+) (uvrC) [Helicobacter pylori strain MT5105]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDIDEAMKQAIINHYQSHLPLMPEQILLS
DCSNEVLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFNLECMPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTTSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=549611 J5D22_RS03970 WP_209505250.1 846228..848012(+) (uvrC) [Helicobacter pylori strain MT5105]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGCGTTTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAACAATGAAATCACGCCCA
ACCCTCGCACAAGCTTACGCATTCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGACTTCCCTATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGATAGGATAGCTAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGTGGGAACAACAAGGCGGT
GTTAGTGAAAATGTTCATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTCAACGGGTTTGACA
TTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GATTGCTCTAATGAAGTGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATATTCTAAAAAAATCGCTCTTAATATCCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTCAATTTAGAGTGCATGCCTTATAGGGTAGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTTCAAAAAAACTCTTATCGGCG
TTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATTGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCCATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGACTAGTAATACTTTTAAATTACTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAAGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.121

99.832

0.96