Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J4T92_RS03900 Genome accession   NZ_CP071975
Coordinates   829538..831322 (+) Length   594 a.a.
NCBI ID   WP_209552499.1    Uniprot ID   -
Organism   Helicobacter pylori strain MT5118     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 824538..836322
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4T92_RS03870 (J4T92_03870) motB 825304..826077 (+) 774 WP_001085363.1 flagellar motor protein MotB -
  J4T92_RS03875 (J4T92_03875) - 826083..826520 (+) 438 WP_001900984.1 hypothetical protein -
  J4T92_RS03880 (J4T92_03880) - 826589..828250 (+) 1662 WP_209552495.1 glycine betaine ABC transporter substrate-binding protein -
  J4T92_RS03885 (J4T92_03885) - 828252..828893 (+) 642 WP_209552497.1 ATP-binding cassette domain-containing protein -
  J4T92_RS03890 (J4T92_03890) - 828905..829084 (-) 180 WP_000468794.1 hypothetical protein -
  J4T92_RS03895 (J4T92_03895) - 829076..829537 (+) 462 WP_000437179.1 hypothetical protein -
  J4T92_RS03900 (J4T92_03900) uvrC 829538..831322 (+) 1785 WP_209552499.1 excinuclease ABC subunit UvrC Machinery gene
  J4T92_RS03905 (J4T92_03905) - 831333..832598 (+) 1266 WP_209552501.1 homoserine dehydrogenase -
  J4T92_RS03910 (J4T92_03910) - 832598..832942 (+) 345 WP_209552503.1 YraN family protein -
  J4T92_RS03915 (J4T92_03915) trxA 833034..833354 (+) 321 WP_000020199.1 thioredoxin -
  J4T92_RS03920 (J4T92_03920) trxB 833360..834295 (+) 936 WP_000564379.1 thioredoxin-disulfide reductase -
  J4T92_RS03925 (J4T92_03925) - 834653..835474 (+) 822 WP_209552505.1 glycosyltransferase family 25 protein -
  J4T92_RS03930 (J4T92_03930) - 835699..835947 (-) 249 WP_000790555.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68646.94 Da        Isoelectric Point: 9.7159

>NTDB_id=549589 J4T92_RS03900 WP_209552499.1 829538..831322(+) (uvrC) [Helicobacter pylori strain MT5118]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSIDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEVLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFNLECMPYRVEIFDT
SHHANSQCVGGMVVYENHAFQKNSYRHYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=549589 J4T92_RS03900 WP_209552499.1 829538..831322(+) (uvrC) [Helicobacter pylori strain MT5118]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCCTCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAATATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTATATGGATTTTTCTATTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTACTCCCTTTAGTTCAAAAGAAA
AATTGCATTAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGAATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCTGCGTTTGAGAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAGGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATTTTATTGAGC
GCTTGTTCTAATGAAGTGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACCATGCATTTCAAAAAAACTCCTATCGGCA
CTACCATTTGAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CGCCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCCAGCAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.306

100

0.973