Detailed information NTG0549120

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: J4Q31_RS09065
• Genome accession: NZ_CP071918
• Coordinates: 1757212..1758279 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159553.1
• Uniprot ID: A0A0T8CF10
• Organism: Streptococcus pneumoniae strain 19A-19343
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1752212..1763279

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4Q31_RS09040 (J4Q31_09050)	treR	1752299..1753009 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
J4Q31_RS09045 (J4Q31_09055)	-	1753166..1754309 (+)	1144	Protein_1811	transposase	-
J4Q31_RS09050 (J4Q31_09060)	-	1754476..1755822 (+)	1347	WP_001814919.1	IS1380-like element ISSpn5 family transposase	-
J4Q31_RS09055 (J4Q31_09065)	-	1756015..1756200 (+)	186	Protein_1813	transposase	-
J4Q31_RS09060 (J4Q31_09070)	amiF	1756275..1757201 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
J4Q31_RS09065 (J4Q31_09075)	amiE	1757212..1758279 (-)	1068	WP_000159553.1	ABC transporter ATP-binding protein	Regulator
J4Q31_RS09070 (J4Q31_09080)	amiD	1758288..1759214 (-)	927	WP_000103702.1	oligopeptide ABC transporter permease OppC	Regulator
J4Q31_RS09075 (J4Q31_09085)	amiC	1759214..1760710 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
J4Q31_RS09080 (J4Q31_09090)	amiA3	1760777..1762756 (-)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39437.04 Da
• Isoelectric Point: 4.8002

>NTDB_id=549120 J4Q31_RS09065 WP_000159553.1 1757212..1758279(-) (amiE) [Streptococcus pneumoniae strain 19A-19343]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPCHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=549120 J4Q31_RS09065 WP_000159553.1 1757212..1758279(-) (amiE) [Streptococcus pneumoniae strain 19A-19343]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTTGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A0T8CF10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.451	100	0.885
amiE	Streptococcus thermophilus LMG 18311	86.761	100	0.868
amiE	Streptococcus thermophilus LMD-9	86.761	100	0.868
oppD	Streptococcus mutans UA159	54.545	99.155	0.541