NTDB

Overview

Name	comYH	Type	Machinery gene
Locus tag	J4Q30_RS10165	Genome accession	NZ_CP071917
Coordinates	1944535..1945488 (-)	Length	317 a.a.
NCBI ID	WP_000345119.1	Uniprot ID	A0A0T7TMT7
Organism	Streptococcus pneumoniae strain 19A-19339
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1939535..1950488

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4Q30_RS10140 (J4Q30_10135)	-	1940296..1940919 (-)	624	WP_000932633.1	hypothetical protein	-
J4Q30_RS10145 (J4Q30_10140)	jag	1940970..1941956 (-)	987	WP_000260019.1	RNA-binding cell elongation regulator Jag/EloR	-
J4Q30_RS10150 (J4Q30_10145)	-	1941975..1942799 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
J4Q30_RS10155 (J4Q30_10150)	rnpA	1942774..1943145 (-)	372	WP_000739246.1	ribonuclease P protein component	-
J4Q30_RS11620	-	1943162..1943293 (-)	132	WP_000768904.1	hypothetical protein	-
J4Q30_RS10160 (J4Q30_10155)	-	1943294..1944484 (-)	1191	WP_000167766.1	acetate kinase	-
J4Q30_RS10165 (J4Q30_10160)	comYH	1944535..1945488 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
J4Q30_RS10170 (J4Q30_10165)	-	1945549..1946136 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
J4Q30_RS10175 (J4Q30_10170)	comGG/cglG	1946273..1946686 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
J4Q30_RS10180 (J4Q30_10175)	comGF/cglF	1946664..1947125 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
J4Q30_RS10185 (J4Q30_10180)	comGE/cglE	1947088..1947390 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
J4Q30_RS10190 (J4Q30_10185)	comGD/cglD	1947353..1947757 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
J4Q30_RS10195 (J4Q30_10190)	comGC/cglC	1947750..1948016 (-)	267	WP_000962026.1	competence type IV pilus major pilin ComGC	Machinery gene
J4Q30_RS10200 (J4Q30_10195)	-	1948018..1948275 (-)	258	WP_000698513.1	hypothetical protein	-
J4Q30_RS10205 (J4Q30_10200)	-	1948507..1949463 (-)	957	WP_233923013.1	N-acetylmuramoyl-L-alanine amidase family protein	-
J4Q30_RS10210 (J4Q30_10205)	-	1949466..1949801 (-)	336	WP_050200954.1	phage holin	-
J4Q30_RS10215 (J4Q30_10210)	-	1949805..1950221 (-)	417	WP_001165344.1	phage holin family protein	-

Sequence

Protein

Download Length: 317 a.a. Molecular weight: 35746.93 Da Isoelectric Point: 4.2434

                                >NTDB_id=549055 J4Q30_RS10165 WP_000345119.1 1944535..1945488(-) (comYH) [Streptococcus pneumoniae strain 19A-19339]

MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT

EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ

AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ

SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide

Download Length: 954 bp

                                >NTDB_id=549055 J4Q30_RS10165 WP_000345119.1 1944535..1945488(-) (comYH) [Streptococcus pneumoniae strain 19A-19339]

ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA

CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC

AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA

GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA

AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA

AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG

GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG

CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA

TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA

AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA

TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA

GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0T7TMT7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comYH	Streptococcus mutans UA140	54.313	98.738	0.536
comYH	Streptococcus mutans UA159	53.994	98.738	0.533

Detailed information NTG0549055